Mitochondria Repair

[jordekorn]

Are you satisfied with the quality?

I’ve never taken it before, and I just started 2 weeks ish ago. I have several things from them and haven’t felt disappointed, maybe with Epithalon, but it just reconstituted oddly, still ended up clear. I guess I feel like Ive heard they charge more but also do have legit coas, I’m alright not testing it myself or finding a group to test, or groups tests I can trust. I saw the ss31 for 10$ more for the same mg, and the mg was 3x each vial of the discord vendor.

 

[Jack.donaghy]

Next week I will be finishing a cycle of tesamorilin/ipmorelin which I am very happy with. My next journey might be to repair my mitochondria. I am in my early 60s so my guess is my mitochondria are in rough shape. I have a ton of questions about this subject. I am on high dose tirz (maintenance) and I am at my target weight. I work out every day. Swimming, hiking, weight lifting. I might be in the best shape I have every been. I have mots-c from sry, ss31 is on the way from Jeep. I recently learned I need to start nad+ first. I will order that soon. I also have 5‐amino 1mq if needed. My questions are:

how do I know my mitochondria need repair?

What can I expect when they are repaired or optomized?

Will my swim times improve?

Will I get stronger?

Do I need more than NAD+, SS31 and mots-c?

What should a cycle look like?

I would love to hear your thoughts and hear about your experiences.

Love your journey! You are years ahead of me and a clear inspiration.

 

[Doug5421]

NR or NMN is cheap if you know where to find & are precursors to NAD, no need to shoot up, just pills. On them currently before my SS-31 comes, which I plan to do a good month or two on, then time off. Don't feel the need for MOTS-C & will take NR indefinitely.

 

[Such1943]

How was the tesamorilin/ipmorelin cycle? Decent HGH alternative, or just get the real stuff? I don't think I'd want to go beyond replacement 2-3 ui levels.

 

[wildcat0367]

mitochondria

Swimmer, anyone in their 60's could use a boost for their mitochondria. I am 69 and Mots-NAD+ and SS-31 made a noticeable difference in energy and workout performance. The issue for me is there is no solid research on dosing these peptides. It took trial and error for me to find out what works for me personally. These peptides are expensive and most say to micro dose them and I tried that but got nothing from any of it doing that. What worked for me, 10 mg SS-31 daily for 20 days. Then ran Mots-C at 10 mg a day and 100 mg NAD+ 3 X a week. I ran 5-Amino 1MQ as well at 50 mg 3 X a day. I eased my doses up until I got noticeable results and this is where I ended up. Ran the Mots and NAD for 30 days and have repeated this twice so far. Everyone is different so we each have to tailor our research to get the results we desire. Post up results when you have tried a cycle and let us all know how it went. Good luck.

 

[50ShadesGreyMarket]

Apologies @swimmer this thread has really taken a turn off topic!

Regarding Ivermectin, it’s obvious idiots are misquoting studies. It’s not a cure for Covid, it’s being used to minimize the effects afterward like nerve regeneration. Ivermectin is for people in third world countries. If you live in the US and Europe and have access to modern healthcare you should be able to cough up enough for newer treatments. Surgeons should be pushing Veklury (Remdesivir) and Paxlovid, they make nearly a million a year and have great health insurance.

 

[swimmer]

How was the tesamorilin/ipmorelin cycle? Decent HGH alternative, or just get the real stuff? I don't think I'd want to go beyond replacement 2-3 ui levels.

I have not yet tried straight HGH. I am very surprised how well ipmorelin/tesamorilin worked for visceral fat and muscle retention while losing weight on tirz. After losing about 50lbs on semaglutide then tirz, my muscle mass and strength suffered. I started KLOW and Tess/Ipa. Within about 1 month my swimmers shoulder pain decreased by 90% I was able to start lifting weights for the first time in years. Quickly my strength and muscle mass increased. Much faster than ever before. Several friends asked me if I am doing AAS or TEST which I have never tried. Without the fat you can really see muscle definition. Unfortunately my swim times stayed the same. I was hoping for at least a little increase. Initially the weight loss helped the swim times but adding tess/iP did not help. Two things I do not like about Tessa/ipa was increased heart rate and water retention. Every week I would gain about 8 lbs. water weight then lose it (pee like crazy) on the 2 days off. Within 10 minutes of my injection my heart rate would increase 5-10 beats per minute. My dosage was 2-4 mg/100mcg for 5 days after swim/weights/or hike. I would then take 2 days off. Hopefully after stopping tessa/iPa I will not lose the gains. I am excited about the mitochondria research that I will soon be conducting.

 

[Tbagger]

I am patiently waiting for my kits to come in for this mitochondrial protocol. I did a 4 week cycle of Mots a while back and I felt amazing! At 2mg EOD, I had loads of energy and endurance. I don't know how bad my cellular health is, but I am 41 and treated my body like garbage most of my life, so I'm guessing pretty bad. It can be rough when you start getting older after living like you were wanting to die young. I'm really excited to try this protocol as I'm trying to lock down my baseline metabolic health before moving onto other areas of research like tesa/ipa and other more fitness based peps.

 

[randompersonrandom]

I didn't notice anything during the NAD upramp (I started at 25mg, but moved to 50 on the second week instead of the third). I started the SS-31 a couple of days early in the protocol because I felt like it. (I WILL do the full six weeks of that, and I won't start the MOTS-C early). I DO feel noticeably less fatigued, but I can't really "call it" for at least two weeks; I'm so susceptible to placebo-effect feels that I can't trust anything until it's been awhile.

 

[swimmer]

I finally received the nad++ from MIX. The vials are larger and amber colored. The SS31 is still on it's way from JEEP. I ordered the SS31 more than 2 weeks ago so it should be here soon. I don't think I can wait. I am still a little nervous about a new pep. If anything happens to me at least my roommate will find me so my cats won't have to chew the face of my lifeless corpse to survive. I thank randompersonrandom for that thought!!

 

[yeddie]

I started the first small dose of NAD+ on Monday night. No particular problems with the injection site, but I did have a bit of trouble falling asleep. Do people generally take their doses early in the day?

I also have SS31 on the way from Jeep and was wondering about what time of day is best for these mitochondria-boosting peptides.

 

[MsGizmo]

oh yeah, make no mistake--I am in full blown midlife perimenopausal mid-life crisis freakout. It's low key and low stakes; I'm happily divorced, I never want for a lover or a friend (separately or in the same person), I have a rich, lovely life and nothing that is passing away is the sort of thing that would leave me with regrets. But I am definitely slightly out of my mind right now, walking around in my high school body, looking gorgeous AND older and trying to keep myself from feeling like those are mutually exclusive, grappling with what it means to me be a middle aged woman and living with the intensity of my emotions just turned WAY up.

It's got me slamming random peptides that promise to optimize my mitochondria. I don't actually really believe that's necessary, but it's certainly entertaining. I AM gonna stop after this, though, and go back to just Klow and Tirzepatide. And my tiny dose of Survo. And maybe epitalon. Shut up.

I've been eyeballing epithalon too, lol

 

[randompersonrandom]

I finally received the nad++ from MIX. The vials are larger and amber colored. The SS31 is still on it's way from JEEP. I ordered the SS31 more than 2 weeks ago so it should be here soon. I don't think I can wait. I am still a little nervous about a new pep. If anything happens to me at least my roommate will find me so my cats won't have to chew the face of my lifeless corpse to survive. I thank randompersonrandom for that thought!!

The worst part is that my cats have had an automatic feeder for years; I fill it up every couple of weeks. If they eat my face, it'll be cause they FELT like it

 

[50ShadesGreyMarket]

Next week I will be finishing a cycle of tesamorilin/ipmorelin which I am very happy with. My next journey might be to repair my mitochondria. I am in my early 60s so my guess is my mitochondria are in rough shape. I have a ton of questions about this subject. I am on high dose tirz (maintenance) and I am at my target weight. I work out every day. Swimming, hiking, weight lifting. I might be in the best shape I have every been. I have mots-c from sry, ss31 is on the way from Jeep. I recently learned I need to start nad+ first. I will order that soon. I also have 5‐amino 1mq if needed. My questions are:

how do I know my mitochondria need repair?

What can I expect when they are repaired or optomized?

Will my swim times improve?

Will I get stronger?

Do I need more than NAD+, SS31 and mots-c?

What should a cycle look like?

I would love to hear your thoughts and hear about your experiences.

I’ve been taking Epitalon to extend the replicative lifespan of somatic cells and Humanin to reduce oxidative stress, promote mitochondrial health, and improve glucose metabolism for years now. It’s anti-aging at the cellular level.

My reasons for starting Sema and Reta are because they have synergistic effects with Humanin in neurodegeneration and metabolic aging, since they act on complementary pathways (Humanin from inside the mitochondria, GLP-1 from systemic/incretin signaling).

Although Sema and Reta don’t directly affect telomeres, they lower systemic metabolic stress like Insulin resistance and chronic inflammation, which indirectly helps preserve telomere function.

I’ve taken SS31 and Mots-c for reducing inflammation but I am on so many other peptides that overlap mechanistically that I don’t feel as reliant on them as I was before.

 

[Mr. Blonde]

I got some NAD+ on the way. Never used but excited to start blasting it. Probably start higher like 50mg or 100mg per shot 3x a week

 

[Ru272]

I guess about six months ago I did it SS 31 then MotS and I do think they helped slightly with energy, I should say the MoTS .. SS was hopefully fixing mitochondria … currently doing 5amino, NAD and MOTS 3-4 days a week and I definitely feel like I can get through my day easily. For reference, I am recently in Meno and my energy was tanked as I barely get 6 hours of sleep… not by choice…… I felt the need to nap daily although Work always got in the way. Now with these I don’t feel like I’m struggling. I mean, I get tired but not exhausted. Working on my sleep day by day. And as a sidenote while I was onEpitalon, I had the best sleep. I did dose at night. (Also on Tirz)

 

[desinr-gal]

NR or NMN is cheap if you know where to find & are precursors to NAD, no need to shoot up, just pills. On them currently before my SS-31 comes, which I plan to do a good month or two on, then time off. Don't feel the need for MOTS-C & will take NR indefinitely.

so where do you buy from? I am always wondering about quality, so if you like yours, please lmk

 

[Doug5421]

so where do you buy from? I am always wondering about quality, so if you like yours, please lmk

NR & NMN can be bought virtually anywhere. I bought mine from both amazon and neuroganhealth. Protocol I'm on is 2-4g daily for 6 weeks then 1g every day after. So far, enjoying the increase in energy, abeit not a huge increase.

 

[Foggy-Hollow]

I got some NAD+ on the way. Never used but excited to start blasting it. Probably start higher like 50mg or 100mg per shot 3x a week

I read here it’s spicy. I picked up buffered from Nexaph and … yes it’s spicy. My first pin I was like “whoah, so that’s what they mean!”

I’ve been going 20mg 3x per week. Picked it up to try to decreasing adhedonia I have with tirz. It does help with energy, and my arguably poor sense of humor is showing up more.

The adhedonia… not really decreased. Prolly a serotonin problem. Boo.

NAD+ does tend to make my hot flashes revisit. Not sure what that counts for?

 

[Mr. Blonde]

I read here it’s spicy. I picked up buffered from Nexaph and … yes it’s spicy. My first pin I was like “whoah, so that’s what they mean!”

I’ve been going 20mg 3x per week. Picked it up to try to decreasing adhedonia I have with tirz. It does help with energy, and my arguably poor sense of humor is showing up more.

The adhedonia… not really decreased. Prolly a serotonin problem. Boo.

NAD+ does tend to make my hot flashes revisit. Not sure what that counts for?

Thanks for your insight