快感缺失……那种无精打采的感觉。

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miss-sanne said:
Oh man ! Now reta is causing me some anhedonia. Hmm... going down in dose to see, if it really is the reta.
I may be accidentally crossing posts here as I quoted you on another thread a bit ago... but do you mind sharing your dosing schedule over time? What did you get up to with no anhedonia? I have god awful anhedonia on tirz (literally even as low as 2.5mg is too much) and basically between quitting entirely or trying reta
 
om777 said:
I may be accidentally crossing posts here as I quoted you on another thread a bit ago... but do you mind sharing your dosing schedule over time? What did you get up to with no anhedonia? I have god awful anhedonia on tirz (literally even as low as 2.5mg is too much) and basically between quitting entirely or trying reta
Sure.

I got anhedonia on tirz high doses, 10 mg and 11 mg.

On Reta I got it on 8 mg, but only after I've been on it for 2 months.

So now I'm down to 6 mg, and feel ok again, most of the time. Otherwise, I'll go further down.

If you feel it on Tirz 2,5 mg, it's likely to come on Reta too. Maybe you should do something else instead, like Cagri, who works differently.
 
miss-sanne said:
Sure.

I got anhedonia on tirz high doses, 10 mg and 11 mg.

On Reta I got it on 8 mg, but only after I've been on it for 2 months.

So now I'm down to 6 mg, and feel ok again, most of the time. Otherwise, I'll go further down.

If you feel it on Tirz 2,5 mg, it's likely to come on Reta too. Maybe you should do something else instead, like Cagri, who works differently.
Thanks so much!!! I will start reta next week and keep you posted in case it helps others.
 
Lately, I’ve noticed a lack of dopamine in other areas of my life, like spending time with family or enjoying leisure activities and I don’t like it. It’s starting to feel more like a “what’s the point of life” kind of thing. I wouldn’t call it depression, because I still have energy and feel generally happy, but the absence of those dopamine hits is becoming more extreme and it’s starting to get to me. I'm on 10mg tirz
 
Lucas said:
Lately, I’ve noticed a lack of dopamine in other areas of my life, like spending time with family or enjoying leisure activities and I don’t like it. It’s starting to feel more like a “what’s the point of life” kind of thing. I wouldn’t call it depression, because I still have energy and feel generally happy, but the absence of those dopamine hits is becoming more extreme and it’s starting to get to me. I'm on 10mg tirz
You could try to reduce to 7,5 mg tirz.
 
Not_Your_Dad said:
I've added a CJC-1295 (no dac) / Ipamorelin blend, mostly because I was also starting a 12 week run of Tesamorelin, and my research suggests added benefits from the Ipa and a somewhat different pathway with the CJC-1295. I was planning on starting with a single pin in the am, then titrating up to a PM pin as well after a week, just to check my tolerance and sides. What I found though, after that first AM pin, was that I felt bright, energized, and focused almost the entire day. So much so that I did the PM pin on the very first day as well.

I think I read this earlier but didn't really READ it for some reason. This is pretty fantastic, it's been a few weeks, how is CJC/Ipa treating you?

I'm still a fan of NAD+ but it's more of an energy lift than feeling "bright."
 
Oh ... I was swabbed for influenza and Covid today. Might need to wait a bit to restart Tirz?

Dropped my antidepressant (Wellbutrin) with my doc's okay. (January, in the dark Midwest?!?) Yah I'm excited. He bumped my ADHD med up slightly and it is helping.

Just gotta get over this cold/flu/whatever. Honey-citrus-ginger tea has been good.
 
miss-sanne said:
I'm beginning the mitochondria protocol soon, excited to see if it can help.

I'm really exhausted these days. Like REAALLY exhausted.

Did you try it ? @desinr-gal @Foggy-Hollow
嘿,我刚完成线粒体疗法!我觉得我的确感觉好多了,也不那么疲惫了,但很难说是不是这个疗法起了作用,因为我同时也在服用 KLOW、依匹隆疗程、苏沃组合,并且增加了运动量。
 
Foggy-Hollow said:
😂 听起来这很符合这群人的作风。

很高兴你感觉良好!
“嘿,伙计们,我找到完美组合了!不知道是什么,但我肯定曾经成功过!” 这就是为什么我不是科学家,我的同事们绝对不会邀请我参加他们的晚宴。
 
我现在减重43磅了。唯一的问题是:即使我减少了1个单位的Reta,心率仍然很高。皮肤有点敏感和易怒……而且脚冰凉。即使在夏威夷也是如此!

我正在使用Tirz、Reta、Klow和Semax这几款产品。
 
desinr-gal said:
我现在减重43磅了。唯一的问题是:即使我减少了1个单位的Reta,心率仍然很高。皮肤有点敏感和易怒……而且脚冰凉。即使在夏威夷也是如此!

我正在使用Tirz、Reta、Klow和Semax这几款产品。
是的 !
 
Thanks for this valuable information!

I'll add my two cents. I'm 48 years old and have been on low-dose Reta for 9 weeks. This week I increased to 2 mg/week. The problem is my increasingly severe anhedonia since I increased to 1.5 mg 5 weeks ago. I don't feel like socializing; people tell me I seem quite sad, even though I feel fine.

I went from 25% to 17%, which is where I am now. My diet isn't very strict for my weight and height, 1500-2000 kcal. I train almost every day, lifting weights and using a stationary bike.

I'm going to see if it goes away; I've seen quite a few posts on Reddit about what happens after a few weeks.

Thanks for your advice.
 
Omxxl said:
Thanks for this valuable information!

I'll add my two cents. I'm 48 years old and have been on low-dose Reta for 9 weeks. This week I increased to 2 mg/week. The problem is my increasingly severe anhedonia since I increased to 1.5 mg 5 weeks ago. I don't feel like socializing; people tell me I seem quite sad, even though I feel fine.

I went from 25% to 17%, which is where I am now. My diet isn't very strict for my weight and height, 1500-2000 kcal. I train almost every day, lifting weights and using a stationary bike.

I'm going to see if it goes away; I've seen quite a few posts on Reddit about what happens after a few weeks.

Thanks for your advice.
I'm sorry you have caught the anhedonia bitch.

It's really so exhausting and blaaaah.

I feel, mine is better these days. I went up toa Reta 8 mg per week again, even though I went to 6 some time ago beause of anhedonia.

For now, working ok.

I do still use the NAC supplement, and nasal Semax and Selank.

I'm hoping, it will just pass over time.

Oh, and BTW, are you F og M ?
 
miss-sanne said:
I'm sorry you have caught the anhedonia bitch.

It's really so exhausting and blaaaah.

I feel, mine is better these days. I went up toa Reta 8 mg per week again, even though I went to 6 some time ago beause of anhedonia.

For now, working ok.

I do still use the NAC supplement, and nasal Semax and Selank.

I'm hoping, it will just pass over time.

Oh, and BTW, are you F og M ?
Hello, what do you mean by F or M? If you're asking if I'm male or female, I'm male.
 
hehe yes exactly, and I see now on your pic that's a male torso , needed to put my glasses on ;-)
 
randompersonrandom said:
我一开始把这句话看成了“很遗憾你得了快感缺失症,贱人”,然后心想“天哪, @miss-sanne !”
我的天啊哈哈……那样也太没礼貌了吧
 
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