High-Dose Tirz Weight Loss

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Congrats. Impressive. I am at 22mg peak on Tirz, so this will help me push towards a peak of 28mg. And for 8 months, wow. Are you doing occasional blood tests? Any out of range results due to higher dosage?
 
DwightTheDelight said:
I just hit overweight on the BMI scale and figured it would be a good time to post an update, since I'm not sure how many other people are above the 15mg/week threshold and it might be useful info to some. My doctor recently told me I need to start wrapping this up and slowing down. High dose Tirz has powered a 217lb loss (48%) in the last 500 days with very minimal side effects.

I've worked my way up to 15mg of Tirz every 5 days for the last 8 months and Glp1plotter estimates a peak concentration of 28mg in my system. I've messed around with adding reta and cagri in during this stretch for short segments, but I've been unimpressed. Ungodly amounts of Tirz does the trick for me.

In terms of diet, I've been slowly increasing average calories since January from 1500 to 2100 the past two months. Despite this increase, I'm still losing fairly quickly. High carb, moderate protein, low fat plus a day or two of fasting per month is melting this saggy azz.

I'm going to begin slowly increasing the days between shots to see how I handle it. Also, I've lucked out in regards to loose skin, despite the fast loss, and will only need my lower stomach addressed surgically. Not sure if diet/occasional fasting played a role in that, but I thought I would have more loose skin than I do.

@nonyabizznez still married! Booyah! I had to text her to make sure though... haven't seen her in a while

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I think youll be surprised what you can accomplish with far less. I lost on 4mgs every 7 days and maint on 3/week.
 
TooBigtoFail said:
Congrats. Impressive. I am at 22mg peak on Tirz, so this will help me push towards a peak of 28mg. And for 8 months, wow. Are you doing occasional blood tests? Any out of range results due to higher dosage?
I've had 5 comprehensive blood tests done since starting in Dec 23 and the only significant changes were in my alt and ast numbers - which drastically improved. Everything else was in normal range from the start until now.
 
@DwightTheDelight - WOWOW! Amazing results... Thank you for the inspiration this morning! ❤️

@Glp1judd - My strategy was to save getting back into my workout routines until I stalled with diet alone - well, I recently upped my physical activity after a long stall & lost another 10 lbs before I could even weigh myself again! 😲 Do what you know you need to - it works! Keep showing those doctors what's up! 😁

Thanks for the carb tips here...I'm jealous of these diets! But already secretly stewing over the possibilities! 😂
 
I heard about your great success and had to come read it for myself.

I’m so proud of you, Dwightypants!
 
elaine77 said:
I think youll be surprised what you can accomplish with far less. I lost on 4mgs every 7 days and maint on 3/week.
You might want to read his actual post at the top, including chart. He started in 2023, lost 217 lbs, so I think he's got a pretty good handle on what he's doing!
 
StonePny said:
@elaine77 Envious of your great results on 4mg, congrats!
Thanks! Im surprised. Things in general are difficult for me usually 😆
 
StonePny said:
You might want to read his actual post at the top, including chart. He started in 2023, lost 217 lbs, so I think he's got a pretty good handle on what he's doing!
I looked at everything and believe my comment is still valid.
 
elaine77 said:
I looked at everything and believe my comment is still valid.
If everyone could lose all of their weight on 4mgs, then the branded meds wouldn't dose up as far as 15mgs. You are likely not the same age, may not be the same sex, don't have the same health considerations...etc. Your comment is valid, but only for you.

Well done on your loss 🙂
 
DwightTheDelight said:
I just hit overweight on the BMI scale and figured it would be a good time to post an update, since I'm not sure how many other people are above the 15mg/week threshold and it might be useful info to some. My doctor recently told me I need to start wrapping this up and slowing down. High dose Tirz has powered a 217lb loss (48%) in the last 500 days with very minimal side effects.

I've worked my way up to 15mg of Tirz every 5 days for the last 8 months and Glp1plotter estimates a peak concentration of 28mg in my system. I've messed around with adding reta and cagri in during this stretch for short segments, but I've been unimpressed. Ungodly amounts of Tirz does the trick for me.

In terms of diet, I've been slowly increasing average calories since January from 1500 to 2100 the past two months. Despite this increase, I'm still losing fairly quickly. High carb, moderate protein, low fat plus a day or two of fasting per month is melting this saggy azz.

I'm going to begin slowly increasing the days between shots to see how I handle it. Also, I've lucked out in regards to loose skin, despite the fast loss, and will only need my lower stomach addressed surgically. Not sure if diet/occasional fasting played a role in that, but I thought I would have more loose skin than I do.

@nonyabizznez still married! Booyah! I had to text her to make sure though... haven't seen her in a while

View attachment 7206
You are an inspiration! I hope you are sharing your story elsewhere also 🙂
 
pavlovs said:
If everyone could lose all of their weight on 4mgs, then the branded meds wouldn't dose up as far as 15mgs. You are likely not the same age, may not be the same sex, don't have the same health considerations...etc. Your comment is valid, but only for you.

Well done on your loss 🙂
Youre doing too much. OP said they titrated up quickly. Im not comparing our height, weight, or anything else. Just throwing out that as they move into being in less than 15 they may still experience benefits. What works for me may not work for everyone but I never said it would. I was just giving a bit of cheerleading for them since they didnt spend much time on lower doses.
 
DwightTheDelight said:
I just hit overweight on the BMI scale and figured it would be a good time to post an update, since I'm not sure how many other people are above the 15mg/week threshold and it might be useful info to some. My doctor recently told me I need to start wrapping this up and slowing down. High dose Tirz has powered a 217lb loss (48%) in the last 500 days with very minimal side effects.

I've worked my way up to 15mg of Tirz every 5 days for the last 8 months and Glp1plotter estimates a peak concentration of 28mg in my system. I've messed around with adding reta and cagri in during this stretch for short segments, but I've been unimpressed. Ungodly amounts of Tirz does the trick for me.

In terms of diet, I've been slowly increasing average calories since January from 1500 to 2100 the past two months. Despite this increase, I'm still losing fairly quickly. High carb, moderate protein, low fat plus a day or two of fasting per month is melting this saggy azz.

I'm going to begin slowly increasing the days between shots to see how I handle it. Also, I've lucked out in regards to loose skin, despite the fast loss, and will only need my lower stomach addressed surgically. Not sure if diet/occasional fasting played a role in that, but I thought I would have more loose skin than I do.

@nonyabizznez still married! Booyah! I had to text her to make sure though... haven't seen her in a while

View attachment 7206
Wow, congrats! Even with losing significantly I’m still obese per my scale.. I’m stuck right now, but I haven’t dosed up very quickly- lost great at 4 mg Reta, until I didn’t. Hit a stall and I’ve worked up to 10 mg, debating going up to 12, because I miss seeing it drop quickly…
 
I am taking 20 mg a week. I was stalled out at 10, then 15. Now I’m on 20 and slowly losing again

I switched to tirz from sema after going from 268 to about 215. Since Jan I’ve gone from 215 - 196.

The loss is slower and stalls are longer. But I’m still dropping a couple pounds a month. Considering Reta or upping my dose. But I’m so close to goal weight and honestly not sure I want to go below 189. I’m 5’11. I might drop to 179 but I need to work on gaining some muscle once I hit my goal.
 
I started out at 265 8 months ago and have more or less stalled at 190. While I would consider 175 to be ideal, my general body composition seems to still be adjusting in a positive way to my current weight. At 64 years old, I would prefer being a little bit chunky to being a frail looking old guy. The turkey neck is tightening up on its own and there is minimal gut wrinkling. Might start hitting the gym this winter to make the final stretch.
 
DwightTheDelight said:
I just hit overweight on the BMI scale and figured it would be a good time to post an update, since I'm not sure how many other people are above the 15mg/week threshold and it might be useful info to some. My doctor recently told me I need to start wrapping this up and slowing down. High dose Tirz has powered a 217lb loss (48%) in the last 500 days with very minimal side effects.

I've worked my way up to 15mg of Tirz every 5 days for the last 8 months and Glp1plotter estimates a peak concentration of 28mg in my system. I've messed around with adding reta and cagri in during this stretch for short segments, but I've been unimpressed. Ungodly amounts of Tirz does the trick for me.

In terms of diet, I've been slowly increasing average calories since January from 1500 to 2100 the past two months. Despite this increase, I'm still losing fairly quickly. High carb, moderate protein, low fat plus a day or two of fasting per month is melting this saggy azz.

I'm going to begin slowly increasing the days between shots to see how I handle it. Also, I've lucked out in regards to loose skin, despite the fast loss, and will only need my lower stomach addressed surgically. Not sure if diet/occasional fasting played a role in that, but I thought I would have more loose skin than I do.

@nonyabizznez still married! Booyah! I had to text her to make sure though... haven't seen her in a while

View attachment 7206
This is truly amazing! Congratulations Dwight!
 
TooBigtoFail said:
Congrats. Impressive. I am at 22mg peak on Tirz, so this will help me push towards a peak of 28mg. And for 8 months, wow. Are you doing occasional blood tests? Any out of range results due to higher dosage?
22mg? Wow.

I thought I was maxed out at 15.
 
I am stalked between 191-196. I keep fluctuating. I’m on 20 mg a week. Considering upping dose or switching to Reta. Anybody switch form geez to Reta ? Results ?
 
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