SS-31 + MOTs-C vs NAD+

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randompersonrandom said:
I'm finishing up this protocol next week. I'm genuinely unsure if it did anything or had any effect, because throughout the whole thing, I was also running tirz, survo, klow, and a week and a half of epitalon.

I plan to wash out everything but the tirz, because I need to get my cholesterol rechecked and want to go on HRT for perimeno, which I assume will need other labs, and after a month or two washout, plan to run a third klow cycle, a thirty day washout, another epitalon, thirty days off, then possibly try this again.
I feel you. Half my brain is saying: Well, you just finished a 20 day cycle of both Epitalon and Semax and you're taking 8 mg of a triple agonist every week, so why would you expect to feel it? The other half of my brain says: Well, it would be nice if I did!
 
Chili777 said:
I feel you. Half my brain is saying: Well, you just finished a 20 day cycle of both Epitalon and Semax and you're taking 8 mg of a triple agonist every week, so why would you expect to feel it? The other half of my brain says: Well, it would be nice if I did!
so much this. "If you do feel something, how on earth are you going to know whether it's one of the nine things you're injecting into your belly fat, or the weight you're losing? Are you just gonna keep injecting all nine things into your belly fat forever if you feel better?" And my inner lab rat just squeaks "SHUT UP THIS IS ALL MAGIC IMA LIVE FOREVER!"
 
I'm really wondering what's causing so many reported MOTSc reactions, if it's the MOTSc itself or specialized excipients used in the puck?
 
Chili777 said:
Cool. Keep us posted.
Finished my last dose of SS-31 today. Came up 1 short, but did not want to reconstitute another vial for 1 dose. I can say, the subject’s energy levels were consistently up for the 6 weeks on SS-31, especially when 100mg of NAD+ were added (twice weekly). The SS-31 was the first time administering daily sh0ts. It was almost sad saying ta ta to that peptide..at least for now.
 
I'm currently on week 2 of SS-31. No NAD.

I started at 2 mg. This week I increased the dose to 4 mg which I will stay at 4mg. I plan to continue for another three weeks before introducing MOTS-c.

SS-31 has provided noticeably deeper/better sleep. I dose around 8pm and go to bed around 10:30pm. I am pleased with the results so far.
 
Peptidesearch said:
I'm really wondering what's causing so many reported MOTSc reactions, if it's the MOTSc itself or specialized excipients used in the puck?
Today, I started the MOTSc portion of the 14 week mitochondria protocol. 1st time administering a dose of MOTSc. It was a 5mg dose. Maybe RS felt a slight sting going in— slowly with a 1/2 pin in the abdomen. I used a trusted and tested grey 40mg vial reconstituted with 1.5 mL BAC. PHEW.
 
Peptidesearch said:
I'm really wondering what's causing so many reported MOTSc reactions, if it's the MOTSc itself or specialized excipients used in the puck?
I dunno, but I'm so over it. Itchy lump the feels dine-sized and lasts two weeks, which means I'm always walking around with five (for a 3x per week schedule) and my belly is no longer big enough to really spread them out, space wise.
 
randompersonrandom said:
I dunno, but I'm so over it. Itchy lump the feels dine-sized and lasts two weeks, which means I'm always walking around with five (for a 3x per week schedule) and my belly is no longer big enough to really spread them out, space wise.
To me, that sounds like an ISR and not and allergic reaction like I had. How much bac did you use? For some peps and a lot of people, the amount of bac you add can make a big difference. The more bac you add, the less ISR issue because it's not as concentrated. (yes, that means more units to inject but worth it)
 
Twowheelr2 said:
Today, I started the MOTSc portion of the 14 week mitochondria protocol. 1st time administering a dose of MOTSc. It was a 5mg dose. Maybe RS felt a slight sting going in— slowly with a 1/2 pin in the abdomen. I used a trusted and tested grey 40mg vial reconstituted with 1.5 mL BAC. PHEW.
I had 10mg vials and used 1ml to recon and had zero feels when I took it.

40mg is in your vial, that could make a difference for sure. I reconned 3 10mg vials into a 3ml cart and the 6 doses I took gave me no issues, except for my allergic reaction that made my face itch. Try using more bac.
 
texmexpep said:
To me, that sounds like an ISR and not and allergic reaction like I had. How much bac did you use? For some peps and a lot of people, the amount of bac you add can make a big difference. The more bac you add, the less ISR issue because it's not as concentrated. (yes, that means more units to inject but worth it)
No, not an allergy; a very common ISR, similar to NAD+ (Even buffered.) I did 3 ml bac to 32mg. I don't want to double that, because I'm too grossed out by huge volume doses; at the concentration I have, it's like 47 units. I'd rather have the lump, but I dislike the choice and am glad the protocol's almost over it, even though I undeniably feel better.
 
I am currently on Reta which I understand helps with mitochondrial health by promoting mitophagy. If instead of repairing the mitochondria with SS-31, you clean out the damaged mitochondria with Reta and let the process ride for a few months, which is plenty of time for turnover and replacement to occur. I would think after a few months MOTS-c would be more effective for someone who had compromised mitochondria. Does my logic hold up here, or am I missing something?
 
texmexpep said:
To me, that sounds like an ISR and not and allergic reaction like I had. How much bac did you use? For some peps and a lot of people, the amount of bac you add can make a big difference. The more bac you add, the less ISR issue because it's not as concentrated. (yes, that means more units to inject but worth it)
I've heard the same from others on increasing BAC, maybe filtering could help as well?
 
randompersonrandom said:
I dunno, but I'm so over it. Itchy lump the feels dine-sized and lasts two weeks, which means I'm always walking around with five (for a 3x per week schedule) and my belly is no longer big enough to really spread them out, space wise.
It's exhausting, I had this happen with Testosterone Subq but it's an oil base and known to cause this. I switched to IM and zero issues ever since. I'm going to filter my Mots-C to see if it helps prevent getting these reactions.
 
NAD+ and Mots-c give me energy and endurance(not like a preworkout like INSANE LABS PSYCHOTIC). I'm waiting on ss31 to be delivered and ready to on board that. SLU maybe next
 
Peptidesearch said:
It's exhausting, I had this happen with Testosterone Subq but it's an oil base and known to cause this. I switched to IM and zero issues ever since. I'm going to filter my Mots-C to see if it helps prevent getting these reactions.

Just so you don't get your hopes up too much; there's nothing I don't filter. I use pens, so I gotta transfer it from vial A to cartridge B anyway, figure it's dumb not to take the four seconds to unscrew the needle, and slap on a filter and a new needle.

Adding more BAC probably WOULD help, it does with KLOW, though the total volume of the dose that gets the right mg amount and doesn't cause an ISR isn't very high, only about 35 units for the one I have. For the MOTS-C, if you don't mind shooting up almost a ml of fluid (for 5mg) 3x per week, then it's likely to be the thing that helps. I just can't bear that; I get the mental image of drinking a cup of cocoa into a pocket of my belly fat and feel ill.
 
randompersonrandom said:
Just so you don't get your hopes up too much; there's nothing I don't filter. I use pens, so I gotta transfer it from vial A to cartridge B anyway, figure it's dumb not to take the four seconds to unscrew the needle, and slap on a filter and a new needle.

Adding more BAC probably WOULD help, it does with KLOW, though the total volume of the dose that gets the right mg amount and doesn't cause an ISR isn't very high, only about 35 units for the one I have. For the MOTS-C, If you don't mind shooting up almost ml of fluid (for 5mg) 3x per week, then it's likely to be the thing that helps. I just can't bear that; I get the mental image of drinking a cup of cocoa into a pocket of my belly fat and feel ill.
Good to know, thanks for sharing.
 
Raptor14 said:
I'm currently on week 2 of SS-31. No NAD.

I started at 2 mg. This week I increased the dose to 4 mg which I will stay at 4mg. I plan to continue for another three weeks before introducing MOTS-c.

SS-31 has provided noticeably deeper/better sleep. I dose around 8pm and go to bed around 10:30pm. I am pleased with the results so far.
Are you using any wearable to track sleep quality? Ss31 wired my research subject and for that reason it was always taken in the am.
 
Peptidesearch said:
I've heard the same from others on increasing BAC, maybe filtering could help as well?
It's definitely worth doing, just to be on the safe side. I'm not great about filtering my own peps but I make sure to filter anything I recon for the family.
 
randompersonrandom said:
No, not an allergy; a very common ISR, similar to NAD+ (Even buffered.) I did 3 ml bac to 32mg. I don't want to double that, because I'm too grossed out by huge volume doses; at the concentration I have, it's like 47 units. I'd rather have the lump, but I dislike the choice and am glad the protocol's almost over it, even though I undeniably feel better.
I just realized I made a typo in this comment. I did NOT have an ISR, I only had an allergic reaction. If I only had an ISR, I'd deal with that and poke on. 😊
 
texmexpep said:
I just realized I made a typo in this comment. I did NOT have an ISR, I only had an allergic reaction. If I only had an ISR, I'd deal with that and poke on. 😊
oh no, you had it right--I was agreeing with you that no, mine isn't an allergy, just an ISR and a common one with MOTS-C. I agree that yours was DEFINITELY an allergy and not worth daring it to get worse.
 
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