breefree31
Recently Joined 🚫No Source Discussion🚫

Hello,
I wanted to get some feedback on histamine responses to Tesamorelin.
Background : I am going on my 5th week of Tesa+IPA cycle. My dosing is 2mg Tesa+300mcg IPA, 5 on 2 off weekly. The first 3 weeks of subQ injections were fine, small itchy response after pinning that would usually go away after 10-15 minutes. This has since changed as of the last two weeks, the initial pinning is fine, but after around 12 hours of dose the itchiness has become more pronounced, and the welting and swelling continually increases and usually peaks in severity within 48 hours.
For comparison, I get allergic reactions to bug bites that are not typical to the histamine response of others, my wife for example. My allergic responses are the same thing large, extremely itchy welts that are a couple inches in diameter or more.
Things I have done so far to try and manage the itchiness : I have tried titration by adding more BAC; 3ML BAC to the 10mg Tesa and that didn't really help. I have also tried to split the dosage in two seperate injections in 2 different spots; one in thigh and one in abdomen and that didn't help, although the thigh injection is less of an annoying itch, but still extremely itchy and warm and welted. I have used OTC Antihistmines llike Ceterizine and Fomatidine and that seems to help the itch for a couple of hours. Additionally, I have let the syringe come to room temp and pinned, that doesn't help.I have also used Anti-Itch creams and Triamcinalone topically and that can help take a bit of the edge off but the welting and itch still persist.
I am on other stacks; "Klow," Semax and Selank, and on Reta 2mg 1x week and there are no ISR associated with these.
Because I also suffer from extreme bite reactions, and also certain seasonal allergies to different types of plants and weeds that has produced a similar reaction, I am leaning more towards getting some testing done to see if my tryptase levels are abnormal.
For people that have similar allergic reactions, has anybody found treatments that have worked for them? I was looking at medicines like Ketotifen or maybe some oral steroids temporarily.
Any feedback is greatly appreciated!
I wanted to get some feedback on histamine responses to Tesamorelin.
Background : I am going on my 5th week of Tesa+IPA cycle. My dosing is 2mg Tesa+300mcg IPA, 5 on 2 off weekly. The first 3 weeks of subQ injections were fine, small itchy response after pinning that would usually go away after 10-15 minutes. This has since changed as of the last two weeks, the initial pinning is fine, but after around 12 hours of dose the itchiness has become more pronounced, and the welting and swelling continually increases and usually peaks in severity within 48 hours.
For comparison, I get allergic reactions to bug bites that are not typical to the histamine response of others, my wife for example. My allergic responses are the same thing large, extremely itchy welts that are a couple inches in diameter or more.
Things I have done so far to try and manage the itchiness : I have tried titration by adding more BAC; 3ML BAC to the 10mg Tesa and that didn't really help. I have also tried to split the dosage in two seperate injections in 2 different spots; one in thigh and one in abdomen and that didn't help, although the thigh injection is less of an annoying itch, but still extremely itchy and warm and welted. I have used OTC Antihistmines llike Ceterizine and Fomatidine and that seems to help the itch for a couple of hours. Additionally, I have let the syringe come to room temp and pinned, that doesn't help.I have also used Anti-Itch creams and Triamcinalone topically and that can help take a bit of the edge off but the welting and itch still persist.
I am on other stacks; "Klow," Semax and Selank, and on Reta 2mg 1x week and there are no ISR associated with these.
Because I also suffer from extreme bite reactions, and also certain seasonal allergies to different types of plants and weeds that has produced a similar reaction, I am leaning more towards getting some testing done to see if my tryptase levels are abnormal.
For people that have similar allergic reactions, has anybody found treatments that have worked for them? I was looking at medicines like Ketotifen or maybe some oral steroids temporarily.
Any feedback is greatly appreciated!