Gone grey!

[lurchy123]

I don't mean my hair! Took the plunge today and ordered some tirz online.

How are you guys storing it before it's reconstituted? Do I need to freeze it or is it ok in the fridge?

 

[Calm Logic]

Almost everyone seems to freeze tirz before recon, especially since a whole kit can be a year supply, depending on dosing and if it is T10 or T15 vs T60/120.

There really is no major advantage to refrigeration since colder is better to help maintain purity and sterility.

 

[keangkong]

Before reconstitution, the peptides you buy are will last several months at room temperature with minimal degradation.

 

[lurchy123]

Almost everyone seems to freeze tirz before recon, especially since a whole kit can be a year supply, depending on dosing and if it is T10 or T15 vs T60/120.

There really is no major advantage to refrigeration since colder is better to help maintain purity and sterility.

Do you take it straight out the freezer and add bac water or let it warm up first?

 

[Ashley2077]

Do you take it straight out the freezer and add bac water or let it warm up first?

I take mine straight out of the freezer and reconstitute

 

[YoYoFat]

The answer to a lot of these basic questions can be found with minimal reading here.

 

[Calm Logic]

From Gemini:

Yes, it's generally recommended to let a vial of lyophilized powder of tirzepatide warm up to room temperature before reconstituting it with bacteriostatic water (BAC water).

Here's why this is a good practice:

* Prevents Temperature Shock: Adding cold BAC water to a room-temperature powder can cause temperature shock. This might affect the drug's stability or how well it dissolves.

* Ensures Proper Dissolution: Allowing the lyophilized powder to reach room temperature helps ensure it dissolves completely and correctly once you add the BAC water.

* Follows Manufacturer Guidelines: While specific instructions can vary, the general rule for many lyophilized medications is to let them warm up. For instance, some instructions for Mounjaro vials specifically tell you to "Remove the vial from the refrigerator" and allow it to warm up.

How to Do It

* Remove from Cold Storage: Take the vial out of the freezer or refrigerator.

* Allow to Warm: Let the vial sit at room temperature for a bit (e.g., 15-30 minutes, or as specified by any instructions you have) so it can reach the ambient temperature.

* Reconstitute: Once it's at room temperature, you can proceed with reconstitution using your BAC water. Remember to gently swirl the vial; don't shake it vigorously.

Important Considerations

* No Freezing After Reconstitution: While the powder is stored frozen, do not freeze reconstituted tirzepatide solutions. Freezing can damage the medication.

* Storage After Reconstitution: After you've mixed it, the solution typically needs to be kept in the refrigerator and has a limited shelf life. Always follow the specific instructions for your product.

* Always Check Specific Instructions: It's crucial to refer to the package insert or any instructions provided by your pharmacist or healthcare provider for the exact tirzepatide product you have. There might be slight variations.

Letting the vial warm up to room temperature before reconstituting with BAC water is a simple step that helps ensure the medication's stability and proper dissolution.

 

[Iamnew2this]

From Gemini:

I always learn something new here, almost every single day! I'm going to let mine sit on the counter for a half an hour and then reconstitute. Maybe, I'll get extra skinny

 

[Pinmebaby1moretime]

I store mine in a hydropeak container in my freezer. There is a maker space near me and I made the vial inserts everyone else is buying on Etsy.

When I’m ready to reconstitute, I take it out of the freezer for about 30 minutes. I reconstitute with hospira bacteriostatic water then filter it into a new sterile vial.

Let me know if you need links to anything or want to know more!

After it’s reconstituted I keep it in my fridge in a vial case- again something I 3D printed on my own for free.

I kept the bac water in my closet where it’s cool and more temperature regulated than other parts of my home.

 

[lurchy123]

I store mine in a hydropeak container in my freezer. There is a maker space near me and I made the vial inserts everyone else is buying on Etsy.

When I’m ready to reconstitute, I take it out of the freezer for about 30 minutes. I reconstitute with hospira bacteriostatic water then filter it into a new sterile vial.

Let me know if you need links to anything or want to know more!

After it’s reconstituted I keep it in my fridge in a vial case- again something I 3D printed on my own for free.

I kept the bac water in my closet where it’s cool and more temperature regulated than other parts of my home.

I'm interested to hear about the filtering. I have read a few things where people have mentioned but what are you filtering out? I'll follow what you're doing sounds logical to freeze it pull it out 30mins prior. I'm going to use a pen for mine cause it's nice and convenient and I've got loads of the pins already so that'll stay in the fridge loaded like a normal Kwik pen. I was going to keep the bac water in the fridge also

 

[lurchy123]

The answer to a lot of these basic questions can be found with minimal reading here.

Its good to talk! Its what forums are for

 

[Calm Logic]

But you don't know what you don't know. So it helps to read as much as you can.

If you had read more, you would have also seen some of us complaining that some new users act like we are their personal search engine, rather than searching the forum themselves.

 

[Bjd4162]

I'm interested to hear about the filtering. I have read a few things where people have mentioned but what are you filtering out? I'll follow what you're doing sounds logical to freeze it pull it out 30mins prior. I'm going to use a pen for mine cause it's nice and convenient and I've got loads of the pins already so that'll stay in the fridge loaded like a normal Kwik pen. I was going to keep the bac water in the fridge also

I hate the questions about filtering. If someone feels like they need to filter - they do not need to be in the gray market. Nurses don't even do that.

 

[Bjd4162]

Its good to talk! Its what forums are for

It is also alot of times what gets pages, people and suppliers banned, in trouble, or shut down.

 

[Calm Logic]

I hate the questions about filtering. If someone feels like they need to filter - they do not need to be in the gray market. Nurses don't even do that.

Nurses are not reconstituting illicit peptides from China, made in unknown labs with no FDA registration. And they don't have to worry about unsterile pieces of plastic or cardboard inside.

But the recon process itself can create particulate matter that would ideally be filtered out. The standards in pharmacy compounding also require filtering.

 

[Iamnew2this]

I hate the questions about filtering. If someone feels like they need to filter - they do not need to be in the gray market. Nurses don't even do that.

It all depends on someone's comfort level and particular/medical needs. It's all up to the individual. You either filter or you don't. It's that simple.

 

[SassyPants]

I'm interested to hear about the filtering. I have read a few things where people have mentioned but what are you filtering out? I'll follow what you're doing sounds logical to freeze it pull it out 30mins prior. I'm going to use a pen for mine cause it's nice and convenient and I've got loads of the pins already so that'll stay in the fridge loaded like a normal Kwik pen. I was going to keep the bac water in the fridge also

If you go to the search function up top you can search and find these questions asked and answered a dozen different ways. In case you didn’t know. Good luck to you.

 

[Calm Logic]

And filtering is just part of the process for preventing pathogens. You want to wipe or spray everything down with 70 percent rubbing alcohol, including gloves. Wearing gloves can help prevent staph from getting in. And if you already have a HEPA air filter, it wouldn't hurt to put it close by.

 

[Pinmebaby1moretime]

I'm interested to hear about the filtering. I have read a few things where people have mentioned but what are you filtering out? I'll follow what you're doing sounds logical to freeze it pull it out 30mins prior. I'm going to use a pen for mine cause it's nice and convenient and I've got loads of the pins already so that'll stay in the fridge loaded like a normal Kwik pen. I was going to keep the bac water in the fridge also

Yeah sure!

So the first thing I did was search here the word filter/ filtering and read what others said! Then I went to chatGPT and tried to find what filter is best for my peptides. It even told me step by step how to filter.

Thing is- I’m a girl who frequents med spas and there are some horror stories about contaminated injections even in those professional settings. I’ve also worked in the burn unit of a hospital where I’ve seen more than one person come in with flesh eating bacteria exposure and it’s never something I’m willing to risk. Like I’ll spend a dollar on a filter, sue me.

Sterility is not guaranteed in grey market. Can we guarantee that each lab follows GMP? Equipment is properly autoclaved, the environment is completely sterile etc.

Even if there is no bacteria there could be micro particles. Glass, dust, residual byproduct…Just months ago, we found out red dye was added to some lipo-c.

Improperly sealed? Any exposure to moisture will grow bacteria. I just saw a TikTok of a state side kitchen peptide seller (pharmatech07) saying his sealing device is broken and held together by rubber bands:

So anyways… 22 µm low protein-binding filter (PVDF or RC).

Here’s the ones I bought: https://amzn.to/4ensiza

Here’s the sterile vials I bought:

2mL amber: https://amzn.to/44afc4Y

10mL amber: https://amzn.to/44qNeAO

The amber provides another layer of protection from light degradation of your peptides so I opted for those!

If anyone is upset I’m using filters, please touch grass

 

[Calm Logic]

Regarding vials:

Vial Source

Anyone have recommendations where to buy vials for aliquots? Amber and clear vials?

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