Enclomiphene Results (Month 1)

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For the cardiovascular system, a steady test level is best. So enclo (with or without HCG) could be better in that regard, though test-u is also an option.

Another option is daily or EOD test-c. Playing with AI, it looks like daily, subq injections of test-c may be worth it.

Gemini said:
The "natural pulse" of Enclomiphene or hCG is often less stressful on the heart than the "sawtooth" of twice-weekly injections.

Comparison: Biological vs. Mechanical Stability

Protocol Stability Profile Mechanism of "Steadiness" CV Stress Impact Enclomiphene Natural Circadian Pulse Mimics natural 24-hour cycle; highs in AM, lows in PM. Lowest; avoids supraphysiological spikes entirely. hCG Only Stimulated Rhythm Triggers steady testicular output; lasts ~36-48h per dose. Low; maintain endogenous "backfill" hormones (DHEA/Prog). Enclo + hCG Hybrid Biological Dual-pathway stimulation; creates a very robust, flat "floor." Low; best for keeping E2 high-normal for heart protection. Test-C (Weekly) High-Amplitude Sawtooth Massive peak at 48h followed by a 5-day crash. Highest ; peak causes BP spikes and thick blood (HCT). Test-C (2x/Wk) Moderate Sawtooth Splits the "oil bolus" in two; reduces peak by ~50%. Moderate; much safer than weekly but still "pulsing." Test-C (Daily) Mechanical Flat-line Eliminates peaks/troughs; mimics a constant drip. Lowest (Inj); prevents the "spike" stimulus for RBCs. Test-U (Slow) Long-Term Taper The "heaviest" ester; releases tiny amounts over weeks. Very Low; most consistent levels over months of time.

Enclo can lower IGF-1, but most/many guys on enclo are already on GH.
 
Zydeceltico said:
Because enclo uses your own natural processing to create test whereas TRT does not and once you're using TRT, your natural ability diminishes.

Albeit, this only works for folks who are still able to produce SOME test. Mine was 400 prior to enclo. I wanted TRT. Doc told me I should try clomid/enclo first and let my body makes its own if it could. Mine can. Test is 750-850 - and all produced by my own body.

Won't work for everyone.
Do you feel like you get the full benefits of exogenous test with enclo? Been on enclo 6+ months. Went from 460 to 1100 total t, 90 to 140 free but estrogen jumped to 103. Started ai and last labs showed estrogen at 59 and free t went to 227. I personally have felt terrible almost the entire time I've been on enclo. But that is probably due to the fact that estrogen has been all over the place. Debating switching to test c just so I have more control over where I'm at. Already have 4 kids and recently got snipped so not worried about fertility. Trying to decide if I stick it out on enclo or just make the switch after my next provider visit.
 
Haven't tried enclomiphene just listened to podcasts and read about it. This is mostly anecdotal, but the guys that like it, like it. The guys that don't, there are two issues. Numbers look good on paper but no symptom relief and also it lowers igf1 levels.

Plus, there is no long term studies as opposed to testosterone that's been around for decades.
 
Calm Logic said:
For the cardiovascular system, a steady test level is best. So enclo (with or without HCG) could be better in that regard, though test-u is also an option.

Another option is daily or EOD test-c. Playing with AI, it looks like daily, subq injections of test-c may be worth it.

Enclo can lower IGF-1, but most/many guys on enclo are already on GH.
I've seen a few sources talking about daily sub q test injections but haven't talked to anyone that is doing this yet. Most of my friends on test are just pinning IM twice a week and liking that. I've found I convert to estrogen quickly so wondering if subq would work better for me if I were to switch from enclo to test c.
 
mraajr said:
It is hard to speak on the water retention because I also take MK-677 and Tesamorelin, both of which can cause you to retain water. I do think I hold a bit of extra water weight, but I am unsure which of the three is causing it.

I have not gained any weight on it, but I am also in a pretty significant calorie deficit on Reta.
Has the Mk-677 caused hunger spikes? How have you been managing that on calorie deficit and reta? My understanding is that you'd want to introduce that and tesa after you've finished hitting your target body comp.
 
Daily or EOD can supposedly help, as can subq. But being a little high on estrogen may be fine. The test:estrogen ratio (between 10:1 and 30:1) is more important than estrogen per se. The higher the test level, the more estrogen you need.

High-normal estrogen is good for the endothelium and for healthy lipids. That's one reason primo can be of the devil without HCG or religiously monitoring estrogen.
 
mraajr said:
A month-ish ago I started taking Enclomiphene (12.5 mg ED). Total testosterone is up from 458 to 1100. Estradiol up from 18 to 41. Free testosterone is up from 63 to 190. The estradiol number is the one I am slightly concerned with, but given the ratio of total test/estradiol, I do not believe it to be too high. Though I have definitely noticed a slight increase in emotional response. Not anger or anything like that. Just that sappy videos and stories seem to make me a bit more emotional than I feel like they probably have in the past, if that makes sense.

It seems like no matter what peptide/drug, etc., I take, I respond extremely well to it. Does anyone think I should possibly cut the dose in half, or are these numbers relatively good? Just looking for some experiences other people have had on Enclo.

I was on clomid before Test. Cyp., it more than doubled my levels but I still felt awful. Enclo. is supposed to be better in this regard but much of what's on the Gray market is supposedly Clomid. E2 is very beneficial for men unless you are having sides from it, so I never worry about it.

View: https://www.youtube.com/watch?v=qeS7j_JU1G4
 
My total testosterone was already 698 and I'm plenty old, I took 25mg of Enclomiphene for 3 months and checked it. Uhhhhhhh 1500+++ and Estradiol went from 35 to 128. I made the mistake of watching Titanic and Joy Luck Club on the same day. Anywho, I just went to 1 - 25mg a week and it took 9 months for it to come back down to TT 958 and Estradiol 58. I just went off of it for 6 months and just started back on it. Just paid $300 for 90 pills, so should last me a year and half.
 
soapysnake said:
Do you feel like you get the full benefits of exogenous test with enclo?
Let's put it this way...................... at 62 years old I began suffering from a weak willy, very weak. Severe ED. Something that I never had in my life. In fact, it was erectile dysfunction that REALLY sparked my journey with tirz believe it or not. I started enclo and tirz at the same time last June.

I am super, incredibly happy to report that my ED is absolutely, 1000% remedied. My lovely girlfriend is quite pleased with this also. So yes - lol - I feel like I am receiving the very full benefits - day after day, night after night - LOL
 
Zydeceltico said:
Let's put it this way...................... at 62 years old I began suffering from a weak willy, very weak. Severe ED. Something that I never had in my life. In fact, it was erectile dysfunction that REALLY sparked my journey with tirz believe it or not. I started enclo and tirz at the same time last June.

I am super, incredibly happy to report that my ED is absolutely, 1000% remedied. My lovely girlfriend is quite pleased with this also. So yes - lol - I feel like I am receiving the very full benefits - day after day, night after night - LOL
lol this is amazing. If anything my enclo use and estrogen jumps were killing my sex drive. Glad to hear this helped you out though 😂
 
That's a big total test gain for 12.5 EN. Seems like it works great for you, just keep that estrogen in check. Many of the peptide vendors have tabs, and grab some anastrozole.
 
You don't need to keep check estrogen in check if you're not having estrogen-related symptoms. The consequences of using too much AI to crush estrogen cna be as bad or worse as having high estrogen.
 
I started Enclo about 2 months ago. It came with a COA and good reviews. I started with 12.5 mg daily. I also stacking with tessa/ipmorelin. My total test went from 670 to 1170. My Estradiol went from mid normal to 58. Shbg was high at 82. Igf1 z-score was +0.03. To lower estradiol and shbg I lowered the dosage to 25 mg every 3 days. The estradiol and shbg stayed the same and total t dropped to 1050 Igf1 z-score bumped to +0.5. I ordered anastrozole and took .5 mg last night. I had a great workout today with new veins visible and less bloat. I feel more relaxed. I am also talking much less than before. I guess high estrogen makes you talk a lot? That makes sense. My ex-wife must have super high estrogen. She never stops talking.😧
 
I tried Enclo for about 3 months because I wanted to maintain testicular function. Why I cared, I don't really know since I'm 42 and already snipped. I think it's just that masculinity gets tied into genitalia for some reason. Anyway, after 3 months, my total test went from about 350 to 600. But I felt even worse than before I started. For some reason my SHBG shot up which lowered my free test and tanked my E2. I'm still unsure how that happened as I was expecting a rise in E2 which is supposedly normal. My doc chalked it up to people are weird and sometimes react oddly to medication since everything else looked normal (slightly elevated ALT but nothing to worry about). But regardless of why, I felt horrible and got ED, was irritable all the time, and just not enjoying life. So I quit the Enclo about 2 months ago and then jumped on the TRT train. I'm now feeling amazing after only 3 weeks of 150mg of test-c.
 
mraajr said:
I was floored when I read the results. I could not believe it got my test that high in such a short amount of time. I didn't want to go straight to test, so I figured Enclo would be worth trying. I am probably retaining some water, but part of that is from MK677 and Tesamorelin also. My estrogen went up almost the exact same percentage as my testosterone, so I figured 41 wasn't too bad, although it was on the higher end of the reference range.
If you are worried about estrogen you could take a aromatase inhibitor , anastrozole. This is commonly prescribed for TRT. If you have more visceral fat you will retain more estrogen as that is where is primarily stored.
 
Can someone please tell me in private if you wish a vendor that currently sells enclomiphene, because the ones I found they are sold out. Thank you
 
vewdew34 said:
Can someone please tell me in private if you wish a vendor that currently sells enclomiphene, because the ones I found they are sold out. Thank you
Need this also. Most enclo is just clomid
 
vewdew34 said:
Can someone please tell me in private if you wish a vendor that currently sells enclomiphene, because the ones I found they are sold out. Thank you

guster said:
Need this also. Most enclo is just clomid

Never bought enclo from them but these are two sites that carry it , these are two sites that some gym bro buddies have recommended to me for some other things.

Enclomiphene – MA Research Chems

maresearchchems.net

https://umbrellalabs.is/shop/nootropics/nootropic-liquid/enclomiphene-liquid/

And I bought some from here just on a whim really, though some of the products that they list make me really wonder what is going on.

Chemical Products | Charlotte, NC - Carolina Chemical

High Quality Laboratory & Industrial Chemicals - At competitive prices with the highest levels of service.

carolinachemical.com
 
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