DNP is a very dangerous drug, it has a low therapeutic index, so the difference between a working dose and a deadly dose is small, which is why people die from taking it.
Bam15 is a weaker mitochondrial uncoupler than DNP, so is significantly less likely to be fatal at high doses, but doses in humans have not been determined as there have been no human studies, and given the type of drug it is, how it works and the very early stage of research even in animals, people taking it is a long way from low risk, especially given the complete lack of any dosing safety studies in humans, and the fact that the animal studies that need to be done before human studies can be considered , have not yet been done, like toxicity and carcinogenesis studies.
It is still being developed as a drug candidate, but the drug companies really want mitochondrial uncoupling drugs that only have effects in the liver, not the whole body , to reduce chances of severe adverse effect or off target effects. They are actually developing a prodrug version of DNP, where the prodrug is converted to DNP in the liver only and works there, and this is probably further along the development process than bam15.
Bam15 definitely looks interesting from the animal studies, but I do not see it as being ready for human testing either in trials or by self selected guinea pigs. Reta is not approved yet, but has a lot of human clinical trial data already and is obviously the safer option.
