注射笔用量精准度/剂量控制方面需要帮助吗？

[mercuryleaf7]

有人能帮我解释一下这是怎么回事吗？

我买了一些V1胰岛素笔，想测试一下它的精准度。测试方法是：把胰岛素注射器插进笔里，调到指定单位，按下活塞，然后查看注射器上的读数，确保和预期的一样。

但是我发现一个很奇怪的现象：第一次操作时，胰岛素剂量总是不足；但之后每次操作，即使只调到2个单位，剂量也都非常准确。

我的操作步骤如下：

1. 将胰岛素笔芯装入笔中。2

. 装上笔针，不断调高笔针，直到活塞接触到笔芯塞，并且有液体流出。3

. ​​然后我把单位调到2个单位，像操作Mounjaro胰岛素笔那样轻轻晃动笔身，确保没有气泡，然后按下活塞，2个单位的胰岛素就流出来了。现在是不是说明一切设置正确，可以注射了？

4. 取出笔针，插入胰岛素注射器。

5. 将刻度盘调至任意单位数（20、60、80），保持注射器和胰岛素笔稳定，然后按下活塞。此时剂量不足

。6. 取出胰岛素注射器，挤出液体，再将注射器放回笔中，再次尝试20单位。这次剂量非常准确。7

. 倒掉液体，尝试2单位、5单位、10单位、20单位等。每次剂量都非常准确。

似乎每次注射的第一剂剂量都会不准确，我在测试的4支胰岛素笔上都遇到了同样的问题，我不明白为什么，因为我一开始就采取了所有正确的步骤来排除空气，并确保活塞与笔芯塞充分接触。

 

[IshimaruKenta]

你的笔都是V1型号的吗？还是也有名牌笔？我不是说V1/V2不好，只是觉得它们的制造精度肯定不如名牌笔。我还没测试过笔的精准度，因为我不想浪费一盒笔芯来验证。也许我应该从速卖通买一些来测试一下。

 

[mercuryleaf7]

Are all your pens V1 models or do you have any name brand ones? Not blaming the V1/V2 but I'm sure they don't have the same manufacturing tolerances that a name brand model would have. I have yet to test my pens for accuracy as I really don't like the idea of having to waste a cart just to find out. Maybe I should buy some from AliExpress and use those to test.

I've got 4 V1 pens off Alibaba and a Lilly Luxura.

The Luxura seemed sporadic with its dosing which is why I've bought these.

I don't understand why the dosing is only inaccurate the first time the pen is used, I am using insulin syringes/needles (so the needle is fixed, extremely low dead space) and I know the issue isn't with that or it wouldn't be displaying the correct amount of units the following times.

And I took all the steps before hand to ensure there was no air etc.

 

[miss-sanne]

Would someone be able to help me/explain what's going on here?

So I got some V1 pens and I decided to test the accuracy where you stick an insulin syringe into the pen, dial up the units, press the plunger then check the reading on the syringe to make sure its the same as what you intended.

However I've noticed something really strange, whenever I do this for the first time it keeps underdosing yet whenever I do it for subsequent tries even as low as 2 units its dead on accurate.

This is what I did:

1. Insert cartridge into pen.

2. Add pen needle and keep dialling up the pen until the plunger is in contact with the cartridge stopper and some liquid comes out.

3. I then set it to 2 units, flicked it similar to a Mounjaro pen to ensure there's no air bubbled and pressed the plunger and the 2 units shot out so we can assume everything is accurately setup now and it should be ready for a dose?

4. Remove pen needle and insert insulin syringe.

5. Dial to 20 units, hold syringe and pen steady and press plunger. Underdoses at around 15-17 units.

6. Remove insulin syringe, squirt out liquid, put it back in the pen and try the 20 units again. Dead on accurate.

7. Get rid of liquid try 2 units, 5 units, 10 units, 20 units etc. All dead on accurate.

It's as if the first dose you would take is always going to be inaccurate and this has been the same on all 4 pens I've tested and I don't understand why as I've taken all the correct steps to begin with to eliminate air and ensure the plunger is in proper contact with the cartridge stopper.

hmm that's strange. is it brand pen ?

 

[mercuryleaf7]

嗯，真奇怪。是品牌吗？

听起来你做得非常正确。

就是一支从阿里巴巴买的普通钢笔。

所以我得出的唯一结论可能是，笔杆活塞在一定行程内行程不准，但超过这个行程后就准了？这

很奇怪，因为按理说后面的行程也应该不准才对！

 

[miss-sanne]

有可能，我也不确定。

我用的是原装的礼来牌 Huma Savvio 胰岛素笔，之前也出现过几次类似的情况，不过不是在刚开始使用的时候。我一直没找到原因，就看到活塞不动了。（当时剂量比较大）

 

[mercuryleaf7]

更新！

我测试了所有4支V1雾化器和一支礼来Luxura雾化器，分别使用了礼来官方烟弹和速卖通烟弹，我自己和朋友都试了一下，想看看是不是我的问题，结果都一样，第一次使用剂量不足。

非常奇怪。

 

[miss-sanne]

更新！

我测试了所有4支V1雾化器和一支礼来Luxura雾化器，分别使用了礼来官方烟弹和速卖通烟弹，我自己和朋友都试了一下，想看看是不是我的问题，结果都一样，第一次使用剂量不足。

非常奇怪。

真是个谜！那就直接扔掉第一剂吧？

 

[mercuryleaf7]

真是个谜！那就直接扔掉第一剂吧？

我本来可以这么做，但我感觉我可能发现了一些其他人没意识到的事情。

不过我想，这种情况肯定发生在每个人身上，只是他们没注意到而已。

更可疑的是，明明是两个人分别测试，用的还是两个不同产地的墨盒，以及两个完全不同的钢笔制造商的产品，却还是出现了同样的问题。

所有这些排除误差的可能性都被排除了，但问题依然存在。