When did tirzepatid stop working

Status
Not open for further replies.

olehandro

GLP-1 Apprentice
Member Since
Nov 23, 2025
Posts
27
Likes Received
34
Location
Slovakia
Я спостерігав дуже хороший ефект від тирзепатиду в дозуванні 2,5-5 мг.

Одного разу я вирішив практикувати голодування. Після ін'єкції тирзепатиду я голодував 60 годин. Все було добре за рахунок голоду, але тіло відчувалося жахливо (біль у хребті та суглобах).

Після цього експерименту я відчув, що тірзе вже не працює так ефективно. Шлунок ніби був повний, але мозок хотів їсти. Ніби щось зламалося. Навіть після титрування до 10 мг нічого не змінилося. Що ви порадите? Можливо, ретатрутид?
 
so after you fasted and started eating again it seemed like tirz had lost its potency for you?
 
mlke6 said:
so after you fasted and started eating again it seemed like tirz had lost its potency for you?
That's right. I don't understand how this could have affected
 
Fasting shouldn’t have any effect. I fasted for 72 hours and wasn’t extra hungry or anything like that after the fast and kept losing weight. How long have you been on a plateau?
 
Dahaka said:
Fasting shouldn’t have any effect. I fasted for 72 hours and wasn’t extra hungry or anything like that after the fast and kept losing weight. How long have you been on a plateau?
already 5 months.
 
olehandro said:
I can't read your first post, but if you have minimal side effects, don't accept such a long stall.

Go up in dose to 12,5 mg, and look again at excercise, food etc.
 
olehandro said:
already 5 months.
Is the issue that you are having that your appetite is stronger than you want or have you stopped losing weight as well? If the problem is hunger then maybe add in a little sema or cagri every week. If you have stopped losing weight then maybe you do need to switch to reta.
 
olehandro said:
I observed a very good effect from tirzepatide at a dosage of 2.5-5 mg.

One day I decided to practice fasting. After the injection of tirzepatide, I fasted for 60 hours. Everything was fine due to the hunger, but my body felt terrible (pain in the spine and joints).

After this experiment, I felt that the tirze was not working as effectively anymore. My stomach felt full, but my brain wanted to eat. It was as if something was broken. Even after titrating to 10 mg, nothing changed. What do you recommend? Maybe retatrutide?
Try a week of pointedly drinking a really lot of water all day long, and eating a lot of protein, starting each meal with the protein. Eat pre-planned, scheduled (small) meals instead of being guided by whether or not you feel like eating ... possibly more than three each day.

Don't fast again!

Retatrutide tends to have much less appetite suppression than tirzepatide, so it's probably not the best choice for you.
 
miss-sanne said:
I can't read your first post, but if you have minimal side effects, don't accept such a long stall.

Go up in dose to 12,5 mg, and look again at excercise, food etc.
This, titrate up if min side effects. If max 15mg is not working, maybe start stacking with Cagri
 
Status
Not open for further replies.

Trending content

Members online

No members online now.

Forum statistics

Threads
2,620
Messages
55,146
Members
1
Latest member
Admin
Back
Top