Did 8mg Reta get you un-stalled? I'm at 12.5mg Terz, about to up it to 15, but only have 6-ish week of Terz left...time to make the switch, I think!TRS123 said:
What dose of reta are you at?
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I went 2-4-6-9-12mg with minimum 4 weeks at each. Currently at 12 with no weight loss
Peotidethrowaway said:
That seems rare, but it’s thing. 5-10% didn’t lose 5% or more of their starting weight.
Are you a non responder across a variety of peptides or GLP?
Peotidethrowaway said:
One in 10 people may have resistance to GLP-1 diabetes drugs
New research suggests that certain genetic variants can decrease the ability of GLP-1 diabetes drugs to regulate blood sugar — a mysterious phenomenon known as GLP-1 resistance.
med.stanford.edu
Like due to that 4-8mg jump. I'm actually 2-4-6-7 now for 2 more weeks. Not sure where I'll go next yet.V6R3W said:
I lost weight on tirz and sema before thatwoundcarping said:
Did you cycle them as in take a break between them and or between them and starting reta?Peotidethrowaway said:
Yepwoundcarping said:
And I know where you’re going with this. There is no scientific evidence that glp receptors burn out, but was 2 years between sema and tirz long enough for you? I think the receptor down regulation theories are a lot of bro science.
I'm working on switching from Tirz to Reta for maintenance. Tirz just has too extreme of an appetite control for me, even at just 5mg. So now I take 4mg of Tirz and added 1mg of Reta 3 days later going to run it for a month, drop Tirz again to 3mg and up Reta to 1.5 and so one until I can find a nice balance of mainly Reta and a microdose of Tirz for added, slight appetite suppression.
Peotidethrowaway said:
That’s an interesting nerve to strike.
These science bros released their study 5 weeks ago.
Article about the study.
Consistent use shows no signs of decreasing efficacy over time,
Here’s a study that links glp1 to pancreatitis and subsequently cancer. There’s a study to prove or disprove everything https://pmc.ncbi.nlm.nih.gov/articles/PMC3920789/
Ps Shotsy fucking sucks
Ps Shotsy fucking sucks
Peotidethrowaway said:
So does your response to Reta, your response to this thread, and probably your response to life.
Don’t know who you’re mad at, but I know it isn’t related to me.
I'm almost a year in. I'm 70 pounds down and have another 30 pounds I want gone in the next year. In the end, I went against most recommendations. I went hard and fast instead of slow and low. Well, for the first 5 months, I followed conventional wisdom and went low and slow and focused on protein and resistance training. Weight loss was sooo slow (about .5-1 pound a month) and then my weight started going UP in November. I said 'fuck this' and shot up to 10 mg reta, 4 mg tirz, and 2mg cagri per week. I still get some cardio and some resistance training, but not a lot. The focus is getting rid of as much fat as possible, as quick as possible, understanding that I may have some muscle that gets lost along the way. I have no regrets.
He's obviously mad it didn't work for him.woundcarping said:
So does your response to Reta, your response to this thread, and probably your response to life.
Don’t know who you’re mad at, but I know it isn’t related to me.
Define working "too well" please.Llanitox said:2mg a week for the last month and it’s working too well I might need to bring it down to 1.5 or 1mg a week.
4.5lbs/week is too fast from what I know. How much have you lost total, starting and current weight? I'm generally curious.Llanitox said:
Only been on it a month started at 99kg and at 94kg thr last 2 weeks has seen a steady 2kg drop a week. I’ve tried to mitigate that by having one refeed day. Basically had more carbs and saltier foods to refill my glycogen. It increased me a kilo for a day did look a lot leaner lol. Down to 94.2 again.BNLFL said:
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