What dose of reta are you at?

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TRS123 said:
I had been at 15mg Tirz in a stall for 6 months swapped straight to 8mg of Reta two weeks ago
Did 8mg Reta get you un-stalled? I'm at 12.5mg Terz, about to up it to 15, but only have 6-ish week of Terz left...time to make the switch, I think!
 
Peotidethrowaway said:
I went 2-4-6-9-12mg with minimum 4 weeks at each. Currently at 12 with no weight loss

That seems rare, but it’s thing. 5-10% didn’t lose 5% or more of their starting weight.

Are you a non responder across a variety of peptides or GLP?
 
Peotidethrowaway said:
I went 2-4-6-9-12mg with minimum 4 weeks at each. Currently at 12 with no weight loss

One in 10 people may have resistance to GLP-1 diabetes drugs

New research suggests that certain genetic variants can decrease the ability of GLP-1 diabetes drugs to regulate blood sugar — a mysterious phenomenon known as GLP-1 resistance.

med.stanford.edu
 
V6R3W said:
Phase 2 studies may have done that, I'm not sure. There was a slight refinement in phase 3. TRIUMPH-4 and TRANSCEND-T2D-1 both did 2-4-6-9-12.
Like due to that 4-8mg jump. I'm actually 2-4-6-7 now for 2 more weeks. Not sure where I'll go next yet.
 
woundcarping said:
That seems rare, but it’s thing. 5-10% didn’t lose 5% or more of their starting weight.

Are you a non responder across a variety of peptides or GLP?
I lost weight on tirz and sema before that
 
woundcarping said:
Did you cycle them as in take a break between them and or between them and starting reta?
Yep

And I know where you’re going with this. There is no scientific evidence that glp receptors burn out, but was 2 years between sema and tirz long enough for you? I think the receptor down regulation theories are a lot of bro science.
 
BNLFL said:
Like due to that 4-8mg jump. I'm actually 2-4-6-7 now for 2 more weeks. Not sure where I'll go next yet.
I bet you're right. 4 to 8 would be a bug jump.
 
I'm working on switching from Tirz to Reta for maintenance. Tirz just has too extreme of an appetite control for me, even at just 5mg. So now I take 4mg of Tirz and added 1mg of Reta 3 days later going to run it for a month, drop Tirz again to 3mg and up Reta to 1.5 and so one until I can find a nice balance of mainly Reta and a microdose of Tirz for added, slight appetite suppression.
 
Here’s a study that links glp1 to pancreatitis and subsequently cancer. There’s a study to prove or disprove everything https://pmc.ncbi.nlm.nih.gov/articles/PMC3920789/

Ps Shotsy fucking sucks
 
Peotidethrowaway said:
Ps Shotsy fucking sucks

😂

So does your response to Reta, your response to this thread, and probably your response to life.

Don’t know who you’re mad at, but I know it isn’t related to me.
 
2mg a week for the last month and it’s working too well I might need to bring it down to 1.5 or 1mg a week 😅.
 
I'm almost a year in. I'm 70 pounds down and have another 30 pounds I want gone in the next year. In the end, I went against most recommendations. I went hard and fast instead of slow and low. Well, for the first 5 months, I followed conventional wisdom and went low and slow and focused on protein and resistance training. Weight loss was sooo slow (about .5-1 pound a month) and then my weight started going UP in November. I said 'fuck this' and shot up to 10 mg reta, 4 mg tirz, and 2mg cagri per week. I still get some cardio and some resistance training, but not a lot. The focus is getting rid of as much fat as possible, as quick as possible, understanding that I may have some muscle that gets lost along the way. I have no regrets.
 
woundcarping said:
😂

So does your response to Reta, your response to this thread, and probably your response to life.

Don’t know who you’re mad at, but I know it isn’t related to me.
He's obviously mad it didn't work for him.
 
Llanitox said:
2mg a week for the last month and it’s working too well I might need to bring it down to 1.5 or 1mg a week 😅.
Define working "too well" please.
 
BNLFL said:
Define working "too well" please.
I reached my targeted weight and then some. Reaching my macro targets daily. Still losing 2kg a week, faster than I expected lol
 
Llanitox said:
I reached my targeted weight and then some. Reaching my macro targets daily. Still losing 2kg a week, faster than I expected lol
4.5lbs/week is too fast from what I know. How much have you lost total, starting and current weight? I'm generally curious.
 
BNLFL said:
4.5lbs/week is too fast from what I know. How much have you lost total, starting and current weight? I'm generally curious.
Only been on it a month started at 99kg and at 94kg thr last 2 weeks has seen a steady 2kg drop a week. I’ve tried to mitigate that by having one refeed day. Basically had more carbs and saltier foods to refill my glycogen. It increased me a kilo for a day did look a lot leaner lol. Down to 94.2 again.
 
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