What dose did you really start noticing its working? Also those that stack?

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jjrama said:
I have been stacking Reta, cjc/ipa and glow. I have seen significant recovery in injuries and I can lift more weight in my gym session. Been awesome. Unfortunately I have not seen weight loss with Reta at all after 6 weeks or skin condition improving from the glow. I am assuming cjc/ipa and glow have been helping my strength training.
Maybe you have been gaining more muscle from the heavier lifting that negates the weight loss? Have you been eating carbs? Some people need them to lose with reta
 
0.250mg, tirz

appetite suppression came on within the following hours after inj., circulatory and/or nerve issues being resolved within the following day or two.
 
WLBLD said:
30lbs loss is Amazing!!

Thank you, I am a particular case too!! I have been going up slowly to make sure & (knock on wood) haven't had any sides (hopefully I didn't just put my foot in my mouth!!)

I didn't have an appetite before starting. I just couldn't lose weight no matter what & that was between 900-1100cal. So I definitely don't have an efficient metabolism, ha ha. Reta actually gave me an appetite which I didn't have before (hopefully turning something on). But I have really good self control with food & sugar cravings are mostly gone.

Like you mentioned I think my prob might be under eating. I'm trying to get 1200 a day. Have a protein shake + collagen & flax seeds as dessert for the cal, some sweetness + the protein & fiber. I do eat whole foods & we cook most of what we eat at home.

I do exercise on & off bc I do have some pain issues. Tirz has helped, was going to switch to Reta, but as soon as I stopped it came back just as bad again, so that is a non weight progress I am really happy with too!!
Thank you, but at your current pace, you will definitely surpass my 30 lbs in six months!!

I think we are twins in every aspect, including exercise.

Eating 900/1000 for a while without losing usually means your body has adapted and is conserving rather than responding.

In that context, the fact that Reta brought your appetite back may actually be a positive signal, not something to suppress too much. At the same time, I would monitor carefully which of the two makes more sense to prioritize when increasing the dose.

It is still difficult to tell whether Reta is more effective for you. The appetite increase suggests activity, but the overall response does not yet appear clearly stronger in terms of weight loss. It may simply be that your body is still adjusting.

Personally, I ended up choosing Tirz and will likely keep Reta for later, possibly to stack once I reach maintenance.
 
Mara_aa said:
Thank you, but at your current pace, you will definitely surpass my 30 lbs in six months!!

I think we are twins in every aspect, including exercise.

Eating 900/1000 for a while without losing usually means your body has adapted and is conserving rather than responding.

In that context, the fact that Reta brought your appetite back may actually be a positive signal, not something to suppress too much. At the same time, I would monitor carefully which of the two makes more sense to prioritize when increasing the dose.

It is still difficult to tell whether Reta is more effective for you. The appetite increase suggests activity, but the overall response does not yet appear clearly stronger in terms of weight loss. It may simply be that your body is still adjusting.

Personally, I ended up choosing Tirz and will likely keep Reta for later, possibly to stack once I reach maintenance.
Im impressed & can't wait to see that kind of number. Just have to keep going

The 900-1100 cal was before I started for years & was never able to loose. Now Im about 1200 I was reading its best to not go under that amount for women.

Thats what I was thinking about the Reta. Hopefully it turned on what ever was completely shut down, ha ha.

I dont know if its the right thing to do but Ive been stacking since week 2. I was going to put the Tirz aside, but after a week I felt pain coming back so I just decided to do both (opened & started using both carts so might as well, ha ha 🙂
 
This week went up to 4mg on the Tirz & going to stay on the 2mg Reta for this week in a few days. Last week didn't lose anything. I know 5mg Tirz is supposed to start getting better but thought the 2mg Reta would be good enough together. I don't have hunger & eating properly, a bit of exercise but I want to see the scale move!!
 
Airborne Daddy said:
Reta at 10mg with 1.5 sema i hit a stall. Started 12.5 mg tirz with 6mg reta and broke the stall.
I guess I have to keep moving up if this weeks 4mg & 2mg don't do anything (which I hope is not the case bc Im only 2.5mo in).
 
I use tirz and had pretty steady loss from my starting dose of 2.5 mg. I didn't need to go above 7.5 mg to reach my goal weight, but I had less to lose than others. Currently able to maintain on 1.25 mg every 1-2 weeks. My wallet thanks me.
 
GroundBison said:
I use tirz and had pretty steady loss from my starting dose of 2.5 mg. I didn't need to go above 7.5 mg to reach my goal weight, but I had less to lose than others. Currently able to maintain on 1.25 mg every 1-2 weeks. My wallet thanks me.
How long did it take you to go up to the 7.5?
 
I’m new here and with that didn’t know you could stack Tirz with Reta. Can someone tell me what the benefit is of using both?
 
There's a lot of conflicting information about it tbh. Lots of people seem to be doing it but I think the general consensus is it's not a great idea. Having said that I've just started reta having been on Tirz for 7 months and while I'm increasing my reta dose over the next month I'll be reducing and coming off Tirz. So I'll be overlapping a stack for a short period . From what I've seen many people use the tirz to help with food noise as reta doesn't give the same food noise control as tirz. But you are doubling up on glp using both which is why I've decided to wean off the tirz completely when I get up to dose of reta that does the job in terms of weight control. I'm mainly going to be using it for maintenance though. So all that probably doesn't help you much but tbh we could all do with more information - but as reta isn't even released yet I don't imagine that will be forthcoming any time soon.
 
Bigdog0628 said:
I’m new here and with that didn’t know you could stack Tirz with Reta. Can someone tell me what the benefit is of using both?
I started on tirz & then I changed my mind to go to reta but after I stopped the tirz I noticed that I hadn't realized tirz helped my pain, so decided to add that back as well.
 
thorien said:
There's a lot of conflicting information about it tbh. Lots of people seem to be doing it but I think the general consensus is it's not a great idea. Having said that I've just started reta having been on Tirz for 7 months and while I'm increasing my reta dose over the next month I'll be reducing and coming off Tirz. So I'll be overlapping a stack for a short period . From what I've seen many people use the tirz to help with food noise as reta doesn't give the same food noise control as tirz. But you are doubling up on glp using both which is why I've decided to wean off the tirz completely when I get up to dose of reta that does the job in terms of weight control. I'm mainly going to be using it for maintenance though. So all that probably doesn't help you much but tbh we could all do with more information - but as reta isn't even released yet I don't imagine that will be forthcoming any time soon.
Yea I didn’t know if there was a benefit to having less of the glucagon receptor and more of the other 2.
 
My loss has been consistent across the doses and reduced weight, not really a given tipping point of efficacy.

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I will be taking shot 52 tomorrow. One year. All Tirz with a mix of peps at the 6-month mark. 15mg. Down 97lbs and 34.6% total weight loss. The Tirz did the majority of the weight loss by month 9.

Never did Reta. Bought a couple of R24 kits and threw them in the freezer. Mostly a novelty purchase, but I convinced myself at the time of purchase that I might need to stack the two. That is becoming increasingly unlikely.

The plan for the next year is to add muscle and complete the body composition. Legs and butt took quite a beating. Leg day is now twice a week. The lower abdomen still needs work to remove the remaining 1 inch of SQ fat. I expect this to take some time. I have never been this focused on self-care in my life.
 
woundcarping said:
My loss has been consistent across the doses and reduced weight, not really a given tipping point of efficacy.

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Thats so Amazing!! I wish I was having as great of results. The past few weeks (even though adding more exercise & been eating less bc no appetite going up) the scale is stuck 🙁

I started my 2nd cartridge of Tirz last week & I think I might have taken 5mg bc I forgot I added 1.5ml instead of 2ml. I planned on 5mg this week anyway, so, ha ha. But I still didn't lose 🙁

You're really having great results!! Congratulations!! Did you stall & that's why you increased?
 
WLBLD said:
Thats so Amazing!! I wish I was having as great of results. The past few weeks (even though adding more exercise & been eating less bc no appetite going up) the scale is stuck 🙁

I started my 2nd cartridge of Tirz last week & I think I might have taken 5mg bc I forgot I added 1.5ml instead of 2ml. I planned on 5mg this week anyway, so, ha ha. But I still didn't lose 🙁

You're really having great results!! Congratulations!! Did you stall & that's why you increased?

I haven’t stalled, I’ve moved my dose up based on tolerability of symptoms and metrics.

My main bumps that lasted more than a few days are primarily related to TRT causing water retention which resolves, and most recently, starting taking creatine which retains water that doesn’t resolve unless you stop taking it.
 
woundcarping said:
I haven’t stalled, I’ve moved my dose up based on tolerability of symptoms and metrics.

My main bumps that lasted more than a few days are primarily related to TRT causing water retention which resolves, and most recently, starting taking creatine which retains water that doesn’t resolve unless you stop taking it.
I was wondering since you went up so high if it stopped working each time so you keep going up?

I think thats what I need to do, just keep going up, ha ha
 
WLBLD said:
I was wondering since you went up so high if it stopped working each time so you keep going up?

I think thats what I need to do, just keep going up, ha ha

Do you see points where I had meaningful plateaus? I don’t.

If you’ve got substantial weight to drop, low and slow seems to be a waste of time. The expensive trials titrated based on time and gave predictable results for the general population.

I’m well above trial dosing, but I expect to pull it back considerably to find my maintenance equilibrium point.
 
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