What did you "nope" out of and why?

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Almost nothing works on me. But I had a bit Respekt with motsc. 5mg Made my histamine reaction tonreta massive...and motsc itself did nothing.
 
peppystrings80 said:
Out of curiosity, have you tried PT as a nasal spray?
I haven’t tried IN, only subQ.

peppystrings80 said:
I've been researching a nasal spray made with PT and oxytocin
This might be a great combination. I’ll be interested to hear how it works out for you. Keep us posted please!
 
Epitalon made me so fatigued I could barely stand up, plus a general feeling of increased sadness and depression.
 
I personally did not like SEMAX nasal spray. after a 20 day cycle all i got out of it was a foggy mindset.
 
DjJoshua said:
I personally did not like SEMAX nasal spray. after a 20 day cycle all i got out of it was a foggy mindset.
To add to this,

The foggy mind was not all day. Plus Stack/interaction factors I am on tirzepatide can subtly influence energy / mood via metabolic changes. These could interact oddly with Semax's neurotrophic effects e.g., tirz sometimes causes transient brain fog in some users during dose adjustments, and layering peptides might amplify that. I have never lacked this but I just never got that whole sharpening focus feeling on semax
 
For me it was KLOW. I definitely felt the anti-inflammatory benefit and I genuinely believe it cut my healing time significantly post surgery (reverse total shoulder replacement). I completed a 12 week course but I dealt with itchy, angry lumps at the injection sites for days after each injection. I constantly had two or three welts on my flank (rotating injection sites) for 3 months. I tried diluting the doses with more BAC, topical and oral antihistamines, lidocaine - nothing really helped. I'll return to BPC/TB and forego the KPV and GHk-Cu for my next foray.
 
Dos-Dox said:
Great question! This will be a good one to follow.

1) MOTS-C - I didn’t have much ISRs with this and finished my protocol, but won’t do it again after learning about how this has such a higher risk/prevalence of anaphylaxis. (Thanks to Calm Logic for gathering and posting the info to allow me to make the decision the risk isn’t worth the reward, which for me was no noticeable positive effect.)

2) PT-141 - I only did the 1 mini pin to assess tolerability and then one regular (2 mg) pin, but I don’t like how it makes me feel at all. The flushing lasts for over an hour and it makes me nauseous. For me, the juice isn’t worth the squeeze on this one.
Do you have links to the mots-c anaphylaxis risk study?
 
Glow, because of BPC-157 and possible tumor growth. I just don't want to chance it
 
Sunflower80 said:
I'll return to BPC/TB and forego the KPV and GHk-Cu for my next foray.
KPV is usually fine and can actually help with ISRs for some people. Maybe you just had problems with the GHK-Cu?
 
Blindman said:
Do you have links to the mots-c anaphylaxis risk study?

Someone I knew almost went to the ER after injecting 5 mg of MOTS-c by IM.

Other anecdotal reports, at least of IM use of MOTS-c:

What is MOTS-c like?

I've been reading up on MOTS-c and it seems quite promising, although some of the claims seem to be really out there. Does it affect gym performance in a noticeable way? Can it help with losing fat while maintaining (or even gaining) muscle? Animal and human clinical trials often use...

glp1forum.com

More generally:

Epi Pen resources?

Has anyone managed to buy some Epi Pens as a hedge against potential anaphylaxis? If so, what was your process? Is there a go-to telehealth that can issue a scrip?

glp1forum.com
 
Dos-Dox said:
Great question! This will be a good one to follow.

1) MOTS-C - I didn’t have much ISRs with this and finished my protocol, but won’t do it again after learning about how this has such a higher risk/prevalence of anaphylaxis. (Thanks to Calm Logic for gathering and posting the info to allow me to make the decision the risk isn’t worth the reward, which for me was no noticeable positive effect.)

2) PT-141 - I only did the 1 mini pin to assess tolerability and then one regular (2 mg) pin, but I don’t like how it makes me feel at all. The flushing lasts for over an hour and it makes me nauseous. For me, the juice isn’t worth the squeeze on this one.
but what about the good stuff of pt-141? did you feel anything? like increase in libido and stuff

asking cz im thinking of trying it
 
latviantower said:
AOD zero effect. Waste of money.
I had a good chat with an AI, and I'd also tried taking the apparent maximum dose for PT 141 (50u) - getting little to no real effect at all, and the AI suggested I take - sildenafil and 80u of PT 141 - well the short version is that this worked, very well... so anyone getting no effect on even the alleged max dose of 50u - I'm living proof that it does work at higher doses...no side effects and no hangovers the next day..
 
SS-31, Epitalon, Semax, Selank, Glow70, Tesamorelin, Ipamorelin.... None of them appeared to do what they were supposed to do, but I did get side effects. I'm using NAD+ and MOTS-c right now and I do feel like I have a bit more energy when I go to the gym.

The Tesamorelin gave me carpal tunnel symptoms. I have backed down to 1.25mg daily and it appears to have helped a bit. Until I am done with the protocol, I assume I won't see the expected effects until I shed the water it causes you to retain.

I think the Glow70 might have helped a little with some tendon issues, but I didn't see any of the "Skin" effects. I'll be switching to the Wolverine stack once the Glow is gone.

As far as NAD+, I might look at the precursors NMN and NR instead of taking the NAD+. A lot of what I read always takes me back to those 2.

I might also get some more MOTS-c after I have completed it for a month or so. I need to take it on its own to see if it is that or the NAD+ that gives me a boost.
 
5AM (but just a single 6+ mg dose). Nothing. Not even one extra pushup.
 
randompersonrandom said:
What's something you thought sounded good, got a kit, started taking, and at some point for some reason said "Oh, you know what? I'm not finishing this out, this is not a good call for me."

Maybe you rethought the potential risks of something, maybe you read one too many accounts of an adverse reaction or had one yourself, maybe you came to believe that the benefits were not as promised.

Mine is MOTS-C. I got almost all the way through the mitochondrial protocol, and then went "Uh...the hard lumps I get at my injection site under the skin do not appear to be going away. I still have the ones from week one. You know what, this one's scary, never mind." (It's been a few weeks since my last dose, and they are finally almost all the way gone, but still, no thanks.)
Mots-C! anything that my body hates that much should Not be injected inside of it..
 
PAPoots said:
SS-31, Epitalon, Semax, Selank, Glow70, Tesamorelin, Ipamorelin.... None of them appeared to do what they were supposed to do, but I did get side effects. I'm using NAD+ and MOTS-c right now and I do feel like I have a bit more energy when I go to the gym.

The Tesamorelin gave me carpal tunnel symptoms. I have backed down to 1.25mg daily and it appears to have helped a bit. Until I am done with the protocol, I assume I won't see the expected effects until I shed the water it causes you to retain.

I think the Glow70 might have helped a little with some tendon issues, but I didn't see any of the "Skin" effects. I'll be switching to the Wolverine stack once the Glow is gone.

As far as NAD+, I might look at the precursors NMN and NR instead of taking the NAD+. A lot of what I read always takes me back to those 2.

I might also get some more MOTS-c after I have completed it for a month or so. I need to take it on its own to see if it is that or the NAD+ that gives me a boost.
Sounds like me.

I tried NMN and NR. Did also nothing for me, even on high dose.
 
MrZardoz said:
I had a good chat with an AI, and I'd also tried taking the apparent maximum dose for PT 141 (50u) - getting little to no real effect at all, and the AI suggested I take - sildenafil and 80u of PT 141 - well the short version is that this worked, very well... so anyone getting no effect on even the alleged max dose of 50u - I'm living proof that it does work at higher doses...no side effects and no hangovers the next day..
Never did viagra, but pt 141 works really well for me
 
Reta. I dosed super slow and couldn't get past 3mg a week and was ravenous hungry and at 4mg horrible diarrhea. I had issues at lower doses but it wasn't all day. Just loose bowels vs the diarrhea at 4mg. I'd run to the bathroom and wasn't going to risk shitting my pants!
 
I haven't "noped" out of anything yet. I am about to finish up a cycle of Kisspeptin, which I won't repeat, no effects that I could tell. I also have a kit of MOTS-c that I am cycling through. I cannot decide if it's doing anything or if its effects are just subtle. I have some days were I feel a bit more wind in the sails; otherwise, no real or consistent improvements in the gym or in energy levels. I am injecting 1 mg daily--may try 2 mg this week.
 
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