Vial Sterility Discussion

[redsaint]

I've been looking at vials to purchase for filtering purposes and stumbled across this video by Peptide Critic:

View: https://youtu.be/Bl_HPyBANwU

Based on his research, it seems that most "sterile" vials sold online are actually just the separate sterile glass and sterile toppers purchased, assembled, and then dropshipped by a third party. The components were once sterile, but there is no guarantee they remained that way once put together.

This is a big concern, and essentially makes filtering pointless. He suggests that if you are going to bother with filtering, you might as well pay more for the more expensive and guaranteed sterile vials with COAs. He recommends ALK in the US, if you can find them.

Everything makes sense to me on paper. I'm wondering if you guys agree?

 

[catwitch]

He suggests that if you are going to bother with filtering, you might as well pay more for the more expensive and guaranteed sterile vials with COAs. He recommends ALK in the US, if you can find them.

Everything makes sense to me on paper. I'm wondering if you guys agree?

Is it weird that those ALK vials aren’t individually packaged? And that box is looking flimsy. The rubber tops are exposed all through the shipping process. I’m glad you posted because I’ve had the same question about sterile vials, but I’m skeptical that this is the answer.

 

[Bioexplorer]

The Amazon Ks-Tek sterile glass vials are relatively inexpensive and individually sealed. The also have plastic cap in place.

 

[ultima thule]

The Amazon Ks-Tek sterile glass vials are relatively inexpensive and individually sealed. The also have plastic cap in place.

Was about to buy Ks-tek, but estimated delivery time for EU is outrageous

 

[DragonOfTheSea]

The Amazon Ks-Tek sterile glass vials are relatively inexpensive and individually sealed. The also have plastic cap in place.

Optics.

Do some more searching on KS-Tek sterility, very inconsistent.. from visible particulates inside to failed tests to leaking vials, I know they're cheap and accessible but I'm certainly not buying them.

 

[redsaint]

Is it weird that those ALK vials aren’t individually packaged? And that box is looking flimsy. The rubber tops are exposed all through the shipping process. I’m glad you posted because I’ve had the same question about sterile vials, but I’m skeptical that this is the answer.

Yeah that also struck me as odd, they're packaged like soda cans. I guess it doesn't matter much as long as the inside is sterile, since we wipe down the outside anyways. It just seems weird to do all of the work to ensure sterility and provide COAs, but then package them as cheaply as possible.

 

[Throwfa]

Was about to buy Ks-tek, but estimated delivery time for EU is outrageous

I purchased mine from Ks-tek and it took about 8 days?

 

[BNLFL]

Was about to buy Ks-tek, but estimated delivery time for EU is outrageous

This is all Amazon. The 3, 5 and 10ml came next day. Just ordered another 10 3ml Tuesday, and here Wednesday. Not sure, but no visible stuff in any of them. I just pull out 2 3ml for reconstituting 2 R50's later.

 

[Bioexplorer]

I believe the concern over Amazon vial sterility is overblown. Proper sterilization is easy enough that it would be very short sighted for a well known vendor to skimp in that area. Occasional particulates in a vial seems more likely but what's the real risk if the vial is properly sterilized? Must be a very tiny particle if it passes a 30 gauge needle.

In my mind, we are all taking a real risk purchasing Peptides from unregulated gray market suppliers. Sure you participate in group testing but does that include endotoxins? Are you sure your vials are truly from the same batch as the test sample(s) or did the vendor mix sources and just label all stock that month with the same number for convenience?

Seems like the much larger risk is the milligrams of actual substance being injected rather than the miniscule risk of some theoretical vial contamination.

And let's not forget the long term health risks of many of these Peptides with very limited human clinical data. Just trying to keep things in perspective. Personally, I have a fairly high risk tolerance.

 

[DragonOfTheSea]

I believe the concern over Amazon vial sterility is overblown. Proper sterilization is easy enough that it would be very short sighted for a well known vendor to skimp in that area. Occasional particulates in a vial seems more likely but what's the real risk if the vial is properly sterilized? Must be a very tiny particle if it passes a 30 gauge needle.

In my mind, we are all taking a real risk purchasing Peptides from unregulated gray market suppliers. Sure you participate in group testing but does that include endotoxins? Are you sure your vials are truly from the same batch as the test sample(s) or did the vendor mix sources and just label all stock that month with the same number for convenience?

Seems like the much larger risk is the milligrams of actual substance being injected rather than the miniscule risk of some theoretical vial contamination.

And let's not forget the long term health risks of many of these Peptides with very limited human clinical data. Just trying to keep things in perspective. Personally, I have a fairly high risk tolerance.

Many of your points may very well be true, however, to me that does not make me go "well f it, I just won't care about contaminates at all." The fact that many of your points may actually be true, is exactly why I choose to filter aseptically into certified vials from certified sources and inject with premium syringes, none of which for me will come from Amazon. At least I know I'm creating a sterile product for myself, mitigating as much additional risk as possible, to what is admittedly inherently already questionable.

But certainly to each their own... We're all entitled to our own opinions and viewpoints.

 

[birdwhacker]

This strikes me as a problem with a simple solution.

Why not buy vials that are actually sterile?

Behold:

Ultra Spec Sterile 2ML (13mm neck) Clear Sealed Glass Vials

In order to receive vials in sealed shrink wrap boxes, please order in multiples of 25 Ultra Spec Sterile 2ML-13mm Clear Sealed Glass Vial, Qty 1 ULTRA SPEC sterile depyrogenated vials are assembled with Teflon coated non-latex chlorobutyl rubber stoppers (conforming with USP<381>) and vials...

www.medical-and-lab-supplies.com

Pyrogen-Free Vials | Astor Scientific

Astor Scientific’s Pyrogen-Free Vials are manufactured and certified to be free of detectable endotoxins and pyrogens, ensuring reliable sample handling for endotoxin testing, pharmaceutical research, and sterile product preparation. Produced under strict quality control standards, these vials...

www.astorscientific.us

Sterile Empty Vials 10 mL Glass with Flip-Top Caps 10/Box

Explore Sterile Empty Vials 10 mL for lab storage, medication prep, and vaccine needs. Ensure safety and precision in every application.

www.mountainside-medical.com

 

[BNLFL]

This strikes me as a problem with a simple solution.

Why not buy vials that are actually sterile?

Behold:

Ultra Spec Sterile 2ML (13mm neck) Clear Sealed Glass Vials

In order to receive vials in sealed shrink wrap boxes, please order in multiples of 25 Ultra Spec Sterile 2ML-13mm Clear Sealed Glass Vial, Qty 1 ULTRA SPEC sterile depyrogenated vials are assembled with Teflon coated non-latex chlorobutyl rubber stoppers (conforming with USP ) and vials...

www.medical-and-lab-supplies.com

Those are only 2ml, but they have bigger ones. The 5ml are actually a little cheaper.

 

[CycleSloth]

If you are unsure whether the vials you have are sterile, it might be worth putting them in a UVC sterilisation box.

 

[Chili777]

If you are unsure whether the vials you have are sterile, it might be worth putting them in a UVC sterilisation box.

There was a long discussion on this topic at Peppy's. UV light doesn't penetrate borosilicate glass so it's ineffective for vials. It does work for pen cartridges though. Your best bet is still purchasing sterile, depyrogenated vials.

 

[WLBLD]

I thought UV light didnt work for cartridges either? Those are also type 1 borosilicate?

 

[Chili777]

I thought UV light didnt work for cartridges either? Those are also type 1 borosilicate?

Head over to Peppy's. The thread has 482 responses going back to 2024. They found that UV light at 265nm lit up UV detector strips inside cartridges and also discuss UV claves available on Amazon. They also have info for turning your Insta pot into an autoclave, as an alternative. STG also has done some testing on this, but it was a while ago so it might have been nuked.

 

[WLBLD]

Head over to Peppy's. The thread has 482 responses going back to 2024. They found that UV light at 265nm lit up UV detector strips inside cartridges and also discuss UV claves available on Amazon. They also have info for turning your Insta pot into an autoclave, as an alternative. STG also has done some testing on this, but it was a while ago so it might have been nuked.

Wow I have seen conversations about it but not sure if it was that one. Yay!! That's so much easier than using the instant pot + I use it to cook so many things they would prob have a food smell, ha ha

 

[Chili777]

Wow I have seen conversations about it but not sure if it was that one. Yay!! That's so much easier than using the instant pot + I use it to cook so many things they would prob have a food smell, ha ha

You need the right one that emits the correct wavelength and not all of them do. They discuss the models that work there also. The main thread is, "Sterilising 3ml cartridges. How do you all do it?".

 

[WLBLD]

You need the right one that emits the correct wavelength and not all of them do. They discuss the models that work there also. The main thread is, "Sterilising 3ml cartridges. How do you all do it?".

Thank you!!