Topical spot-reduction of fat (aminophylline cream)

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Noerofthings

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Here is a 2006 study on topical aminophylline cream used on the waist to spot-reduce fat in...well, the waist: https://dom-pubs.pericles-prod.literatumonline.com/doi/10.1111/j.1463-1326.2006.00600.x. These are their results:

quoted said:
The reduction in waist circumference was 11 ± 1.0 cm in the aminophylline cream group and 5.0 ± 0.6 cm in the control group (p
 
Oooh I’m so glad you brought this up!! I’ve been researching this as well and would love to find some somewhere to experiment with!!!
 
I would have thought this was technically impossible, but you have evidence of a trial with statistically significant results. I tried to find the study but only got the abstract, but it said there had been other trials saying it worked for thigh fat, and blood levels of the drug were undetectable and no side effects. Did not say how many people in the study. Given how many either snake oil - don't work or invasive - do work, treatments there are for this issue I wonder why it did not take off?
 
This would be my dream. On Reta and doing weight training now and just watching my boobs and butt melt away while my waist stays the exact same size.
 
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