The trend of unproven peptides is spreading through influencers and RFK Jr. allies

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keangkong said:
Yet the solutions that worked were very much products of modern medicine - tirzepatide, a sleep study, and I suspect you use CPAP too. I suspect much of the disillusionment with modern medicine is due to people having an inflated expectation that modern medicine can cure every ailment. Modern medicine is not that powerful. Yet I'm only alive today due to modern medicine, which treated my thyroid cancer.
I'm happy for that, Keangkong !

And I do vote to your words.

I can't believe how many of my patients think, I'm their doctor, their psychologist, their social worker, their friend, their priest, their...

I feel, it's changed in the last 20 years a lot.

It's like I'm responsible for their lives, yet people won't do the necessary themselves.

I have a patient with very dysregulated T2DM, it doesn't matter what I tell her, she still eats whatever and doesn't work out.

How can I cure that.

It's just very complex.

I always respect their choice, but I won't hold back saying what I find necesary, - it is my job.
 
Foggy-Hollow said:
Exactly.

I’m “only” 35 pounds overweight. My blood pressure increasing. It’s getting harder to be active. Otherwise my numbers are fantastic. F48. I asked My GP for help losing weight, I had been logging, small deficit but should have been enough, and things weren’t budging. My GP gave me a recommendation to take a walk after dinner. No mention of even a nutritionist.
Oh I get so angry with that. WTF.

I never deny a patient glp's, if they are a candidate. Why would I ?

And why would the doctor decide what is good for you, it's your choice.

We lay out the options, patients decide.

And that includes glp1.

I think, I was 40-45 pounds overweight and insulin resistant + high lipids + perimenopause, how was a walk gonna help me.

I was hungry all the time because of the metabolic dysfunction.

Great advice lol.
 
keangkong said:
I had a friend who rejected modern medicine. She ended up dying of breast cancer. I had another friend who wouldn't take the recommended statins and high blood pressure medicines. He believed those medicines were unnecessary since he was a long distance runner. He ended up having a widow maker heart attack. He needed a quadruple bypass operation to survive. He is no longer a runner due to the extensive damage to his heart. It's funny how those who criticize doctors for treating health conditions with medication are often those most willing to take multiple untested supplements. I remember watching an interview with RFK Jr. where he stated he takes multiple supplements, but could remember the names of most of the supplements he takes.
My husband was the opposite. He took his medicine like a good little boy and they nearly killed him. They said he had high cholesterol and gave him half of the maximum dose of lipitor right out of the gate. 2 weeks later he had a heart attack. They did a cardiac cath and saw that everything was fine. No plaque build up and no blockages. So they put him at the maximum dose of lipitor and added tricor. 2 months later he had another heart attack. Did another cardiac cath .. again nothing. Messed around with his meds some more and over the next 3 years he had 2 strokes, a 3rd heart attack and developed diabetes. Doctors told me that lipitor couldn't possibly have caused the diabetes or trigger the heart attacks. While I was telling everyone that he was fine before they put him on the pills. 100% fine. The pills made him sicker and sicker. So finally he listens to me and weans himself off the meds except for the diabetes stuff. He slowly got better. That was 22 years ago. The damage to his pancreas is permanent so he will always be a diabetic now. Yes, he still has slightly high cholesterol too. big deal.

Oh, and before anyone asks, he has never been overweight. Furthermore lipitor was linked to pancreatitis later on and that can lead to diabetes. But I was the crazy one back then.
 
MsGizmo said:
My husband was the opposite. He took his medicine like a good little boy and they nearly killed him. They said he had high cholesterol and gave him half of the maximum dose of lipitor right out of the gate. 2 weeks later he had a heart attack. They did a cardiac cath and saw that everything was fine. No plaque build up and no blockages. So they put him at the maximum dose of lipitor and added tricor. 2 months later he had another heart attack. Did another cardiac cath .. again nothing. Messed around with his meds some more and over the next 3 years he had 2 strokes, a 3rd heart attack and developed diabetes. Doctors told me that lipitor couldn't possibly have caused the diabetes or trigger the heart attacks. While I was telling everyone that he was fine before they put him on the pills. 100% fine. The pills made him sicker and sicker. So finally he listens to me and weans himself off the meds except for the diabetes stuff. He slowly got better. That was 22 years ago. The damage to his pancreas is permanent so he will always be a diabetic now. Yes, he still has slightly high cholesterol too. big deal.

Oh, and before anyone asks, he has never been overweight. Furthermore lipitor was linked to pancreatitis later on and that can lead to diabetes. But I was the crazy one back then.
I'm sorry for you, I never heard about that. It's not on the side effects list in Denmark, the pancreatitis, but the hyperglycæmia is.

I'm glad you found you own way and kept listening to yourself.

Modern medicine is limited in many ways, and marvellous in others, no doubt about it.

I sometimes meet patients who have some really rare side effects to different medicines, and not listed ones.
 
keangkong said:
Yet the solutions that worked were very much products of modern medicine - tirzepatide, a sleep study, and I suspect you use CPAP too. I suspect much of the disillusionment with modern medicine is due to people having an inflated expectation that modern medicine can cure every ailment. Modern medicine is not that powerful. Yet I'm only alive today due to modern medicine, which treated my thyroid cancer.
I don't have any beef with modern medicine. We've been able to do some remarkable things in the past 100 years or so that have dramatically improved the quality and quantity of life for the majority of humanity.

What I have a beef with is the way modern medicine is often dispensed, at least based on my experiences in the United States. I go to see a physician (well, not any more, usually an APRN or PA now), who is quadruple booked all day long to keep that fucking insurance revenue flowing, because the CEO of the healthcare group has a Porsche in the driveway and SOMEONE needs to make the payment on it. I get 15 actual seconds of this person paying attention to me - the rest of their time is ticking boxes on an iPad or clicking through shit on a computer. And in that 15 seconds they decide what is wrong, no matter what I actually have to say.

But now, I have access to some of this advanced technology medicine on my own. I don't have to be some insurance company's bitch. I don't have to jump through all these hoops and hope, and beg, and cajole on the chance that lightning will strike and not only will a provider listen to me but insurance will decide I'm allowed to have a medicine that a provider thinks I need and would help me. I can learn, research, educate myself, and make some decisions for ME (nb. not decisions for you or anyone else, just me ), but FDA has a problem with that. And FDA has a problem with that because, just like the assholes who used to work at Treasury and then move to private finance and have a problem with regulation, the same assholes who used to work at FDA now work in Pharma, and what is Pharma's primary objective? R.O.I to their investors. And we can't be having Tirz available at some price other than $1400 / month, now can we?

Anyway, that's where I'm coming from on this particular topic.

And I'm glad you beat the thyroid cancer and are here!
 
Not_Your_Dad said:
I don't have any beef with modern medicine. We've been able to do some remarkable things in the past 100 years or so that have dramatically improved the quality and quantity of life for the majority of humanity.

What I have a beef with is the way modern medicine is often dispensed, at least based on my experiences in the United States. I go to see a physician (well, not any more, usually an APRN or PA now), who is quadruple booked all day long to keep that fucking insurance revenue flowing, because the CEO of the healthcare group has a Porsche in the driveway and SOMEONE needs to make the payment on it. I get 15 actual seconds of this person paying attention to me - the rest of their time is ticking boxes on an iPad or clicking through shit on a computer. And in that 15 seconds they decide what is wrong, no matter what I actually have to say.

But now, I have access to some of this advanced technology medicine on my own. I don't have to be some insurance company's bitch. I don't have to jump through all these hoops and hope, and beg, and cajole on the chance that lightning will strike and not only will a provider listen to me but insurance will decide I'm allowed to have a medicine that a provider thinks I need and would help me. I can learn, research, educate myself, and make some decisions for ME (nb. not decisions for you or anyone else, just me ), but FDA has a problem with that. And FDA has a problem with that because, just like the assholes who used to work at Treasury and then move to private finance and have a problem with regulation, the same assholes who used to work at FDA now work in Pharma, and what is Pharma's primary objective? R.O.I to their investors. And we can't be having Tirz available at some price other than $1400 / month, now can we?

Anyway, that's where I'm coming from on this particular topic.

And I'm glad you beat the thyroid cancer and are here!

I'm a big fan of both modern medicine and free market economic principles. Yet the problems of healthcare in the US are enormous. Since the US spends the most, per capita, on healthcare, we should have the greatest healthcare system in the world. But we don't.
 
I'm a fan of modern medicine as well, it's the delivery system that is broken. I grew up in the 60s and 70s. I only got two vaccines, polio and smallpox as a kid. I've had all the major childhood diseases and almost died 3 times. I remember twice when kids i knew died from what is now preventable disease. Back then you found out from a neighbor or sibling. I've always been a proponent of vaccines because of that experience. People don't remember the "good old days" when death was all around us and a fact of life.

The profit motive has overtaken the distribution of healthcare with everyone in the delivery chain wanting their cut. I'm just trying to live out the rest of my years being as healthy as possible. I do see my doctor regularly, but I'm getting to the age where one major health issue could wipe out my retirement. I'll do whatever I can to prevent that and peps factor into that equation.
 
MsGizmo said:
My husband was the opposite. He took his medicine like a good little boy and they nearly killed him. They said he had high cholesterol and gave him half of the maximum dose of lipitor right out of the gate. 2 weeks later he had a heart attack. They did a cardiac cath and saw that everything was fine. No plaque build up and no blockages. So they put him at the maximum dose of lipitor and added tricor. 2 months later he had another heart attack. Did another cardiac cath .. again nothing. Messed around with his meds some more and over the next 3 years he had 2 strokes, a 3rd heart attack and developed diabetes. Doctors told me that lipitor couldn't possibly have caused the diabetes or trigger the heart attacks. While I was telling everyone that he was fine before they put him on the pills. 100% fine. The pills made him sicker and sicker. So finally he listens to me and weans himself off the meds except for the diabetes stuff. He slowly got better. That was 22 years ago. The damage to his pancreas is permanent so he will always be a diabetic now. Yes, he still has slightly high cholesterol too. big deal.

Oh, and before anyone asks, he has never been overweight. Furthermore lipitor was linked to pancreatitis later on and that can lead to diabetes. But I was the crazy one back then.

You point out an unfortunate aspect of modern medicine: Some people have bad reactions to medication. In your husband's case, even if he read the prescribing information for the drug at the time, he would have seen nothing about the pancreas. Much is still unknown about the drugs we take. One of the unknowns about the GLP-1 drugs that produce the most weight loss is that we don't know if they'll work for the rest of our lives. To be clear, we do have studies showing that semaglutide and tirzepatide will work for over three years without losing their efficacy. But what about 10, 20, or 30 years? We still don't know. We have pre-semaglutide GLP-1 drugs that have worked and kept off weight for 15 years. It seems likely that the tirzepatide and semaglutide will work as long. However, what seems likely doesn't always happen in medicine.

I've always been pro-statin. When friends have said their doctor recommended they take a statin, I've always encouraged those friends to take a statin. Several months ago, I started experiencing an ALT level that was 10 times the upper limit of normal. It turns out the Lipitor that I had been taking for 20 years was causing the problem. My cardiologist switched me to pitavastatin, another statin drug. Although the numbers are not nearly as high as they were, I still have elevated liver enzymes. Will I keep taking the pitavastatin? I'll talk to my hepatologist about that later this month. I may have to switch to a PCSK9 inhibitor.
 
MsGizmo said:
My husband was the opposite. He took his medicine like a good little boy and they nearly killed him.

Holy cats that's crazy. I totally believe you, doctors don't even believe their own. GOOD FOR YOU for sticking up for your guy! <3 That's so much to go through.

One thing changed, and a problem occurred. How do we fix the problem? Sigh.
 
I wonder how many people discover that Ozempic and Mounjaro are peptides, and then start to wonder what other peptides there are out there for various things. It does quickly become like a hidden cheat sheet you think people have been keeping from you. Align that with a booming chinese grey market, social media etc and you have all the ingredients for a population wanting to bypass traditional medicine supply routes.
 
UncrossSelector said:
I wonder how many people discover that Ozempic and Mounjaro are peptides, and then start to wonder what other peptides there are out there for various things. It does quickly become like a hidden cheat sheet you think people have been keeping from you. Align that with a booming chinese grey market, social media etc and you have all the ingredients for a population wanting to bypass traditional medicine supply routes.

I'm definitely one of them. I was on Rx Ozempic not too long ago, and just casually surfing reddit looking for info and stumbled upon some random dude saying something about grey and the forum called glp1forum.com 😀 I'm still can't wrap my mind that i was paying 100x more for a 'legit' Semaglutide, Grey's GLP-1 is way more legit imo given that you are doing test group and all that jazz.
 
Me too. I was looking for some Tirz after failing on compounded Sema, at $500 a month, about 6 months ago and asked a friend who has recently lost weight. She said, "Forget that. Reta is where it's at now!". I asked, "Whazzat?", and the rest is history. I read everything I could find for a couple months before ordering anything and I'm still reading.
 
I know more than one person who started GLP1s recently, because they saw a BlackFriday sale!

I just don't get it. I have nothing to say other than, "maybe you want to talk to your regular Dr about that"? They have no interest and wouldn't trust my commentary anyway.

Like, I spent time looking stuff up before I talked to my Dr. We discussed it and set up a plan for tests and prescription, I read more. I got the prescription, I read more. Insurance ended, I read more, and knew about compounding already so went to a compounder. I started planning my exit to grey, and read more, joined more groups, learned crypto. I lurked and started commenting, and read more and joined more groups, and went grey while I still had a stockpile. And still I read more.

I'm guessing they have a reasonable chance of either expensive failure or a severe medical event even with the pens and "standard protocol".
 
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