Stopping GLP-1 Drugs Triggers Weight Regain 4x Faster Than Ending Exercise

[trojanpeptide]

Newer study declaring what we already know...

Stopping weight loss drugs linked to weight regain and reversal of heart health markers​[archived internal link]
Average regain is 0.4kg/month and all weight lost likely to be regained in under 2 years

Weight regain faster after stopping weight loss drugs than after dietary weight loss programmes

 

[JoonyO]

Newer study declaring what we already know...

Stopping weight loss drugs linked to weight regain and reversal of heart health markers ​
Average regain is 0.4kg/month and all weight lost likely to be regained in under 2 years

Weight regain faster after stopping weight loss drugs than after dietary weight loss programmes

Which, if true, lends weight ( no pun intended ) to those who say they'll stay on 'em forever.

Some people loathe the idea.

 

[dogmom]

I wonder if it depends on how long you are on it. At this point I've been on glp1s for almost 3 years. I've gone at least 4 weeks without any glp1s and my eating and weight stays the same. However, I think if I would have stopped after 6 months I probably would have gained everythng back and then some.

 

[swimmer]

When my insurance first cut me off ozempic I gained 20 pounds in 2 months.

 

[ambot88]

I am 100% sure I would re-fatten pretty quickly off the meds, like I can tell even at the end of the week that I'm having a lot more trouble making good choices.

 

[Habibibi]

You should see my ldl cholesterol when I go off statins for a month

 

[Mr.Tired]

"Weight regain faster after stopping weight loss drugs than after dietary weight loss programmes."

I don't find this at all surprising or an indictment of the effectiveness of glps.

Weight loss through diet and exercise involves forming new habits and massive lifestyle changes. It would only make sense that slacking off on exercise or a diet plan will result in a more gradual reversion, while stopping glps without having made any other lifestyle changes will be a lot more abrupt.

Maybe I'm misunderstanding something though. The article didn't get into the weeds with the participant data.

I'm curious to see the results from people who combine glps with diet and exercise, and maintain the latter two after stopping the peptides.

 

[cygnus]

This is just physics. Exercise really only burns so many calories; it is woefully deficient when it comes to weight loss when compared to calorie deficits, which is what GLPs are good at creating. Nothing new here, just silly headlines to make people scared.

 

[Twowheelr2]

When you come off any diet. You’re looking at the same stats. Weight watchers, keto, carnivore, paleo. Go back to your previous routines and you’ll go back to your previous weight.

 

[dogmom]

When you come off any diet. You’re looking at the same stats. Weight watchers, keto, carnivore, paleo. Go back to your previous routines and you’ll go back to your previous weight.

I wonder what the true stats are on say for example WW for regain. My sister used WW many years ago and lost about a 150lbs in 2 years and then we had a death in our family and she gained 175lbs back in almost a year, like shockingly fast.

My sister is now on a glp1, has lost 220+ from her highest and is like 5lbs away from not being obese for the first time in her life. She will probably be on a glp1 forever, as I will too. Our whole family has dealt with obesity.

 

[m100568]

"Weight regain faster after stopping weight loss drugs than after dietary weight loss programmes."

I don't find this at all surprising or an indictment of the effectiveness of glps.

Weight loss through diet and exercise involves forming new habits and massive lifestyle changes. It would only make sense that slacking off on exercise or a diet plan will result in a more gradual reversion, while stopping glps without having made any other lifestyle changes will be a lot more abrupt.

Maybe I'm misunderstanding something though. The article didn't get into the weeds with the participant data.

I'm curious to see the results from people who combine glps with diet and exercise, and maintain the latter two after stopping the peptides.

I can't find the study, but I recall a study from maybe 20 years ago about who were the small percentage of individuals who kept the weight off. The conclusion, as I recall, is that the few who kept the weight off rearranged their whole lives around the concept of maintaining their weight. They were laser focused and nothing else mattered. Not work. Not family. Nothing. Dinner out with the family and blow the calorie budget -- nope. A family event that interfered with the workout -- nope. Take a job with time commitments that interfered with the weight loss lifestyle -- nope.

I don't think I could live like that if I wanted to. And I don't want to.

 

[trojanpeptide]

I asked ChaptGPT how much of a maintenance dose would be needed if I hit my target weight using 4 mg a week. It responded 8 mg.

 

[thatkatmat]

That's why I've stockpiled enough to last me forever

 

[tubby]

There's a saying that goes: You can't outrun a bad diet.

The idea is that you can't lose significant weight from exercise alone. You have to fix your diet!

Makes sense that the reverse would hold true and reverting to your old diet would lead to much faster weight gain than reverting to your sedentary behavior.

 

[Gr33dyOctopus]

That's why I've stockpiled enough to last me forever

Right?!

 

[Gr33dyOctopus]

There's a saying that goes: You can't outrun a bad diet.

The idea is that you can't lose significant weight from exercise alone. You have to fix your diet!

Makes sense that the reverse would hold true and reverting to your old diet would lead to much faster weight gain than reverting to your sedentary behavior.

I haven't heard that one, but i have heard " You cant outrun your fork" lol

 

[94brian49]

TBH i don't mind taking them forever. But ofcourse it would be best if im not.

 

[FRMN01]

If I have to take glp1 forever, I will. It will be cheaper and healthier

 

[Grogu]

It seems like the news media loves telling this story. I think it's all part of our society's facsination/obession with fat shaming, as if obesity is not a disease for some people but a lifestyle choice.... And that glp-1 are somehow "cheating".

I don't recall Lilly or NN ever saying that these medications were a cure for obesity.

 

[Cmoney]

Newer study declaring what we already know...

Stopping weight loss drugs linked to weight regain and reversal of heart health markers ​
Average regain is 0.4kg/month and all weight lost likely to be regained in under 2 years

Weight regain faster after stopping weight loss drugs than after dietary weight loss programmes

I think this holds true for all weight loss because the problem isn’t the drugs. The problem is we live in very glutinous times with convenience being less expensive and more accessible than back in the olden days of food is fuel for survival. My friend got bypass and changed nothing in here life that would insure her results are permanent as did my sister. The mindset is, food is for rewards and involved in every occasion. It’s a scary fact not forcing a scientifically proven lifestyle change causing the results being short lived. The drugs/surgeries provide the body tools, and us forced discipline. The discipline is what’s needed on our end to carry the success in the long run. And I’m no saint or have mastery over my relationship with food. It’s a long process to reframe this aspect paired with accountability. You’ll also find transfer addiction. Usually alcohol/nicotine. (Both sister and friend rely heavily on those) and admittedly so. my vape is basically my adult pacifier. And that’s because I’ve not mastered discipline or gained control of my Brain yet. (Something I’m working on) but yes. The progress will revert and results will diminish but not because of the drugs. Big Pharma and healthcare wants us fat and unhealthy. And they can eat a bag of eggplants. Because over my dead body will I ever be the fat friend. I love it over here on the skinny side of life. Skinny privilege for girls (like me) is the same for men along side muscle privilege. Probably more so muscle privilege because it highlights commitment, control, and discipline.