I agree. I filter with 0.22u . This is all 'research' quality anyway.Calm Logic said:
So what is the verdict with reconstituting Cagrilintide then?
- Thread starter Raidenfat2fit
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Same.Calm Logic said:
Same samecygnus said:
This^^TooBigtoFail said:
Yeah that's why I wanted to have this discussion, alot of the data around the concerns with cagrilintide are pretty old, with cagrisema very likely to be on the market by the end of this year, I figured us folks in the grey space would have a good enough grasp of the safety profile.TooBigtoFail said:I use AA (Acetic Acid) 0.6%. I test the pH with a Defirm Litmus Test Strip with 4 colors as I could not get good results with regular paper. I also like the Hydrion Paper Strips 0.0-6.0 pH (or 5.5-8.0pH) as they have a decimal precision.
Read a study that cagri at pH 7.4 deteriorated by 45% after 10 days. Novo use 3.5-4.5pH in their product description. For that reason, I add AA since one vial last me 5+ weeks. I end up using about 2/3 AA 0.6% and 1/3 bac to get ~pH 4.0. No AA does not sting. AA is not a good pH for most bacteria to grow. Most peptides do not need AA for reconstitution (aod9604 maybe?)
On fibrils, you may be reading old material. "The amylin-analog cagrilintide contains 14E and 17R mutations to create a salt bridge, stabilizing the central helix structure. It includes 25P/28P/29P mutations to reduce the protein’s propensity to form fibrils". I know Novo could be lying but lawsuits are expensive. I feel pesticides, nitrates, etc will do me in before fibrils.
I stopped cagri 6 mths ago as it made me too nauseous but starting again this week to loose the last 10-15# and I have 15 vials on hand. I could go one day with no food. No appetite at all.
All I can say is I am glad there are people here who understand the science much better than I do. I spend a lot of time searching terms & concepts online.
I'm also having trouble finding AA. Is there a trusted name brand (a la Hospira bac water)?
Thank you.
TooBigtoFail said:
I hope you don't mind my asking.... How do you test the pep pH, just wet the strip using a syringe? I know it's a very basic question.TooBigtoFail said:
I'm also having trouble finding AA. Is there a trusted name brand (a la Hospira bac water)?
Thank you.
underground supply has bothMeedzMoar said:
Thank you.
On Underground, I have not seen his pure 0.6% AA for a while. I only see '3% glycerin + 1% acetic acid + 0.9% benzyl alcohol. pH = 3'. Maybe is ok. I never tried. Been getting AA from Quality Research Chemicals. Pfizer has AA .25% but is for IRRIGATION. That means is not filtered fine enough for injection. That is why I filter. A gamble.CNCCurrency said:
I use it for AOD and cag. It does have a ph of 3. I mix it with regular bac to get a ph of 5TooBigtoFail said:
Look at it this way, if you’re wrong, the Alzheimer’s will make sure you forget about your mistakes.Raidenfat2fit said:
SameCalm Logic said:
Do you know that insulin is also prone to create/form fibrils?Raidenfat2fit said:
Imagine all the people who have taken insulin all these decades... Do you see them with Alzheimer?
Fibrils that are created in the vial will be "stuck" in your injection site. They are too big to easily migrate, or even if they migrate they don't pass the blood brain barrier.. Too big
The fibrils you have to be afraid of are the ones formed" inside the brain " not on a vial..and the insulin users are proof of this
I know this is a little old but when I was buying through middle man vendor, they sent a 3ml BAC water with the cagri order.Gohengrin said:
Lyophilized said:
Moreno Valley? By Lake Elsinore?
Lyophilized said:
Sooo what happens? "Body has a foreign object" type of programming? Irritation, pus, etc?
Because English is not my native language, to answer your question I used the search IA. I don't like to use it but it easyer for answering your questionFoggy-Hollow said:
"
Insulin fibrils, which cause firm, palpable subcutaneous lumps known as insulin-derived amyloidoma, occur at common insulin injection sites due to repeated, non-rotated injections. These, often called "insulin balls," typically form in the abdomen, thighs, buttocks, or upper arms
The removal of insulin fibrils—technically known as localized insulin-derived amyloidosis (LIDA) or an "insulin ball"—primarily relies on surgical intervention or strict site rotation. Unlike common lipohypertrophy (soft fatty lumps), amyloidoma fibrils are firm and do not regress quickly on their own"
I was hoping to find recon tips on this thread.... I'm on 8mg of reta weekly, was 12mg but my sleep was terrible. My sleep is a little better but I've been at 212# for about 3 months and my hunger is outof control. I picked up a 10mg of Cagri to test, but I'm not sure what the easiest way to recon it for starting weekly doses of .125 and .25 mg.
Current history in case it affects dosing or the hope Cagri helps be get in the down slope.
Also on TRT, Tesa, mots-c, nad+ and ipa. The tesa and ipa, most likely are causing my CTS, so I backed of them and the nightly CTS has almost subsided. I thought after the water dropped, I'd are a few pounds drop. Not.
I feel doing with 1ml night be too hard to get the right dose. Even at 3m, it looks odd to me coming out at .75 units on pepcalc.
Hints on the math appreciated
Also, it's bowling night and my thoughts are fuzzy.
Current history in case it affects dosing or the hope Cagri helps be get in the down slope.
Also on TRT, Tesa, mots-c, nad+ and ipa. The tesa and ipa, most likely are causing my CTS, so I backed of them and the nightly CTS has almost subsided. I thought after the water dropped, I'd are a few pounds drop. Not.
I feel doing with 1ml night be too hard to get the right dose. Even at 3m, it looks odd to me coming out at .75 units on pepcalc.
Hints on the math appreciated
Also, it's bowling night and my thoughts are fuzzy.
I do 5mg bottle of Cagri with 2 ml BAC and do a 2mg shot every 6 days between Reta pins. 2mg is 80 units so a vial for me is 2.5 pins.
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