Reta histamine reaction! Has anyone had Reta have a histamine reaction with swelling with a large red area around injection site with itching!

[CraigLSU]

Has anyone had Reta have a histamine reaction with swelling with a large red area around injection site with itching!

 

[BNLFL]

Nope, I got a bruise once.

 

[Cannonball72]

Never. Did the you see COA?

 

[TazaTaza]

Nope, nothing happens, no bruise or itching. It felt like I used water. I use a generic, no name brand 6mm 31G noodle from the 'Zon so nothing fancy, goes in smooth like butter doesn't hurt and no issue with pulling/pushing

I've been on forums/groups for the brand stuff for ~2 yr and I'm ngl I never heard ppl having "histamine reactions" until I stumbled in the grey side of things. I get the vibe you have a bad batch or your water is bad or your noodle is bad

 

[CraigLSU]

Yea he’s used 2 different suppliers but his wife uses the same with no problems. It’s very strange!

 

[lessthanhalf]

Localised injection site reactions are very common with semaglutide and tirzepatide, have not seen as many people online mention it for reta , but given the molecule is nearly identical, it makes sense for it to happen with reta as well. Too long since I read the studies to remember how common it was there. It is not normally the bac water, it is normally the drug that you have an immune reaction to.

The thing that concerns me a bit with your reaction is the size. Most ISR's are fairly small. Even the tiniest bit of evidence for a generalised allergic reaction should make you stop using it, and if large reactions are occurring then you might have to stop it anyway and switch to tirz instead. Cross reactions to different GLP's are rare so switching should solve the problem.

 

[on2jinm]

Has anyone had Reta have a histamine reaction with swelling with a large red area around injection site with itching!

 

[Mr. Blonde]

Never from reta. The only thing that ever gave me an itchy bumpy spot was from CJC 1295 without dac.

 

[badsr71]

No histamine reaction from any of my friends/family (just over 30 of us) from Reta. MOTS, that's a different story, especially at higher doses.

 

[Mr. Blonde]

No histamine reaction from any of my friends/family (just over 30 of us) from Reta. MOTS, that's a different story, especially at higher doses.

I didn't get it from Mots. I was blasting 10mg, 3x per week. I also didn't get much anything else from it. Guess I am already optimized. Am jealous of everyone that gets results from Mots. Lucky bastards.

 

[badsr71]

I didn't get it from Mots. I was blasting 10mg, 3x per week. I also didn't get much anything else from it. Guess I am already optimized. Am jealous of everyone that gets results from Mots. Lucky bastards.

Wow. How long did you run MOTS? I'm doing a different protocol this go around, with NAD+. Started at 200mcg/day, titrating up an additional 200mcg/day every couple of weeks. So far, so good. Low and slow!

 

[dokterp]

Has anyone had Reta have a histamine reaction with swelling with a large red area around injection site with itching!

One time, I had the same reaction. One week later pinned with same vial, waited with epipen, but no reaction. Don't know what did caused this.

 

[DragonOfTheSea]

Has anyone had Reta have a histamine reaction with swelling with a large red area around injection site with itching!

Never with Reta or Tirz.

 

[Mr. Blonde]

Wow. How long did you run MOTS? I'm doing a different protocol this go around, with NAD+. Started at 200mcg/day, titrating up an additional 200mcg/day every couple of weeks. So far, so good. Low and slow!

6 weeks...I think.

 

[piccolo101]

I'm on week 6 and nothing yet. The only time that I have had reactions is from pinning ghk-cu on my stomach. I switched to my glutes and no reaction so far.

 

[Summer48]

The same thing happened to me many times but using a Mounjaro pen from EL but since I moved to the gray stuff nothing at all. Some of those red lumps used to itch like crazy

 

[exploitedworkerbee]

This happens to me with tirzepatide reconstituted with bac water. It does not happen if I reconstitute with sterile water. Doesn’t happen with any other peptides, reta+bac is fine, something about the blend of tirz and bac. You can try sterile water and see if that helps.

Before i discovered the bac water connection I would spray the area with flonase after injection and that knocked it down a bit.

 

[BNLFL]

Nope, nothing happens, no bruise or itching. It felt like I used water. I use a generic, no name brand 6mm 31G noodle from the 'Zon so nothing fancy, goes in smooth like butter doesn't hurt and no issue with pulling/pushing

I've been on forums/groups for the brand stuff for ~2 yr and I'm ngl I never heard ppl having "histamine reactions" until I stumbled in the grey side of things. I get the vibe you have a bad batch or your water is bad or your noodle is bad

Noodle? Pretty sure you meant needle, unless that's some new hip term to use.

 

[CraigLSU]

Localised injection site reactions are very common with semaglutide and tirzepatide, have not seen as many people online mention it for reta , but given the molecule is nearly identical, it makes sense for it to happen with reta as well. Too long since I read the studies to remember how common it was there. It is not normally the bac water, it is normally the drug that you have an immune reaction to.

The thing that concerns me a bit with your reaction is the size. Most ISR's are fairly small. Even the tiniest bit of evidence for a generalised allergic reaction should make you stop using it, and if large reactions are occurring then you might have to stop it anyway and switch to tirz instead. Cross reactions to different GLP's are rare so switching should solve the problem.

Yea I agree! They were fairly large and looked bad!

 

[ambot88]

a friend of mine has been getting giant red welts from the reta, same batch as me - she's tried all the tricks I could think of but every week it was worse so she has to discontinue use.