PT-141 experience

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Calm Logic said:
As a reminder, PT-141 is only FDA approved for women and for only some women at that (as Vyleesi for acquired, generalized hypoactive sexual desire disorder (HSDD) in premenopausal women).
If you're going to point that out you should at least ask your chatbot buddy (not to be confused with your Peptide Buddy) for the history on it being studied in men, what concerns arose, if that related to dosing method imprecision (e.g. nasal VS injection) or is likely to represent a broader risk, and who specifically should heed that concern. I think that all would be valuable history for those researchers out there who may be pondering their options (and perhaps if it might be wiser to wait until other research they're already doing "pays off" first). 🙂
 
tubby said:
If you're going to point that out

As I have said one way or another, the dosing for many men is too damn high at 1.75 mg (as it as for me), potentially risking priapism more than Viagra/Cialis. So that it is approved for only some women at that dose, makes more sense.

I think PT-141 would be best with something else (whatever that would be) for a more well-rounded or less "locked in" experience, which could reduce the risk of priapism.

Some meds like anti-psychotics or trazodone could be problematic with PT-141:

The Hard Facts on Drug-induced Priapism (Long-lasting Erections)

www.medsafe.govt.nz
 
Calm Logic said:
For postmenopausal women, an article from 2019, with PT-141 being used successfully by a 73-year-old Suzanne Somers:

https://people.com/tv/suzanne-somers-husband-sex-shots-sex-twice-day/

(Somers died in 2023 from metastatic breast cancer.)
“I usually say I sleep through one of them. That’s usually that one at 4 o’clock in the morning"

🤣🤣
 
On Meso, one guy's partner moved to the spare bedroom. That may have been the guy who took 3 mg.

One piece advice at Meso was to microdose PT-141, which should be enough with E2 in range, prolactin low.

On Reddit, Sudafed and/or cold shower if necessary to prevent prolonged, overnight erection:

https://www.reddit.com/r/Biohackers/s/EsBcEWcLBt
 
Calm Logic said:
On Meso, one guy's partner moved to the spare bedroom. That may have been the guy who took 3 mg.
🤣🤣 That's what he gets for hoarding it all. Sharing is caring.

Calm Logic said:
On Reddit, Sudafed and/or cold shower if necessary to prevent prolonged, overnight erection:
Good to know!
 
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