MOTS-C and SS31

[cloratheshadow]

Do you HAVE to cycle SS31 to notice benefits of mots? I just did my first 2mg dose of mots and I’m just wondering if I absolutely have to run SS31? Haven’t seen a very reasonable price for it and apparently it makes you really tired? I’m already chronically exhausted. Is it just some people who need it? And also will I feel the MOTS-C fairly quickly to know if I really need to refigure things?

 

[wulf00777]

I heard if you take motsc every other day you don't get the tiredness issue. I can't say I feel anything on either motsc or Ss31 but at least I'm finally losing weight with tirz and motsc and by lowering my calories to 800.

 

[cloratheshadow]

I heard if you take motsc every other day you don't get the tiredness issue. I can't say I feel anything on either motsc or Ss31 but at least I'm finally losing weight with tirz and motsc and by lowering my calories to 800.

800 is very extreme are you weighing your food? Have you had bloodwork done? No adult should be eating 800

 

[wulf00777]

800 is very extreme are you weighing your food? Have you had bloodwork done? No adult should be eating 800

Yup they keep telling me that but it's the only thing that has worked and I feel fine so I'm going with it. People who haven't lived with lifetime obesity don't understand the challenges.

 

[Notthatguy]

Yup they keep telling me that but it's the only thing that has worked and I feel fine so I'm going with it. People who haven't lived with lifetime obesity don't understand the challenges.

right there with you brother.... but dang 800 calories.

 

[wulf00777]

right there with you brother.... but dang 800 calories.

Yup it's extremely difficult to have any kind of life at 800 calories but if I'm dead it won't matter.

 

[myopicmystic]

Yup they keep telling me that but it's the only thing that has worked and I feel fine so I'm going with it. People who haven't lived with lifetime obesity don't understand the challenges.

I hope you’re able to work back up to over 1000 because 800 must be miserable

As for the MOTSc and SS31, I haven’t figured that out yet. I guess it depends on what you’re looking for from the MOTSc. I eventually will probably cycle the SS31 first when I get around to trying the mitochondrial protocol. What price point are you seeing?

 

[Collo4sho]

Do you HAVE to cycle SS31 to notice benefits of mots? I just did my first 2mg dose of mots and I’m just wondering if I absolutely have to run SS31? Haven’t seen a very reasonable price for it and apparently it makes you really tired? I’m already chronically exhausted. Is it just some people who need it? And also will I feel the MOTS-C fairly quickly to know if I really need to refigure things?

I am asking the same question. I just started ss31 and will start motsc after a week. I'm only staggering them to make sure if there is a noticeable difference then I know which one it is. So far, no noticeable changes with the ss31. Being that it's quite pricey, I will not reup my supply of it after this cycle if I don't feel it's necessary.

 

[Ryanking11]

I heard if you take motsc every other day you don't get the tiredness issue. I can't say I feel anything on either motsc or Ss31 but at least I'm finally losing weight with tirz and motsc and by lowering my calories to 800.

i think 800 calorie intake will be extremely dangerous. Be very careful your body doesn’t start to shut down

I jumped straight to mots c every other day and never used ss31 first

 

[KosmikVoidX]

If it makes any difference to you I started mots-c a few weeks ago and didn't feel anything. In fact, may have felt worse energy wise but that also could have just been life circumstances.

However, I started ss-31 which I was going to do first but the mots arrived first and I'm inpatient lol. Anyways, started the protocol of ss31 5mg 5 days a week, and mots 5mg the other 2 days for 3 weeks then go mots 5MG M,W,F and nad the other days. Found that specific protocol somewhere online and since I was already on the mots I decided to try it.

Anyways since adding in the ss-31 I feel my energy has improved significantly after the first week. So might be worth trying it if you feel like the mots isn't doing anything!

 

[chewonmysac]

Do you HAVE to cycle SS31 to notice benefits of mots? I just did my first 2mg dose of mots and I’m just wondering if I absolutely have to run SS31? Haven’t seen a very reasonable price for it and apparently it makes you really tired? I’m already chronically exhausted. Is it just some people who need it? And also will I feel the MOTS-C fairly quickly to know if I really need to refigure things?

Just switched to mid-afternoon pins on SS-31 and works great. Running MOTS-c 5mg every other day in the morning fasted. This is my second cycle, and yes, it made me tired in the AM on the first cycle. On day 11 of 30 of SS-31. I am really starting to feel the synergy.

 

[Tcah2456]

Do you HAVE to cycle SS31 to notice benefits of mots? I just did my first 2mg dose of mots and I’m just wondering if I absolutely have to run SS31? Haven’t seen a very reasonable price for it and apparently it makes you really tired? I’m already chronically exhausted. Is it just some people who need it? And also will I feel the MOTS-C fairly quickly to know if I really need to refigure

Mot c functionality will depend on your mitochondrial health try this

Morning fasted 5-10mg per day for 15-30mg per week , split into 3x weekly

4 weeks on 60-120mg per cycle

followed by 4 weeks off

 

[mybodyisasewer]

i think 800 calorie intake will be extremely dangerous. Be very careful your body doesn’t start to shut down

You would be horrified to learn how long some of our ancestors would go on 0 calories.

 

[woundcarping]

You would be horrified to learn how long some of our ancestors would go on 0 calories.

Yeah but they all died!

 

[cloratheshadow]

You would be horrified to learn how long some of our ancestors would go on 0 calories.

Life expectancy was like…30

 

[dancs]

800 is very extreme are you weighing your food? Have you had bloodwork done? No adult should be eating 800

If you've been losing weight or been trying to for longer than 6-12 months, and you're hitting plateus left and right, and lowering your calories down to 800, I strongly strongly recommend you start over.

What I mean by that is, take a break. 30-60 day break from taking your current stack(s) and start taking other peptides OR take a break period to allow your body's tolerance to come back down.

OR

If you haven't been working out or at the very least, walk after your meals, I recommend you do that. Rather than starving your body to the point where now your body is in extreme mode - trying its hardest to keep the calories (hence why it's so hard to lose just a little bit of weight). It think your body is literally dying of starvation. You need to reset that.

Or change up your tactic. Maybe keep the Mots-c if you just started, but take out Tirz and implement reta and/or AOD-9604.

Up you calories to maintenance or a few hundred above maintenance - yes you may regain some weight, but your body will normalize as time goes by and you'll be able to retake the original compounds and lose weight again.

Or at the very least, take walks right after your meals...

I'm suggesting these based off my experience when it comes to long term weight loss, taking different peptides/compounds, and exercising.

I understand every case is relative, but 800 calories is crazy....

Nothing but love for you and I'm fortunate to be here because this forum is full of good people!

 

[Ryanking11]

You would be horrified to learn how long some of our ancestors would go on 0 calories.

That’s all they knew. They didn’t choose it

 

[lessthanhalf]

800 calories is hardly extreme. There are piles of studies on VLCDs or very low calorie diets of around 400 calories per day and sometimes over quite long periods of time, up to a year or so, that was the way of losing weight for those with severe obesity without surgery in the olden days before GLP's. Usually most calories are protein.

It is a low enough calorie intake to have possible issues with electrolyte imbalances, and enough to make fatigue more of an issue, so some level of medical checking up might be a good idea.

It is a very low calorie intake to only just be losing weight, unless you have already lost a lot of weight and or been on a low calorie intake for a long period of time, so that metabolic adaptation has reduced energy expenditure a lot. Or you are very small. My energy expenditure dropped in half from 145kg to 75 kg so that at the start I lost 6kg per month on 1600-1800 kcal/day, and by the time I got to 75kg, weight loss had stopped and that calorie intake was what was required to keep the weight off, but that calorie intake is lot more tolerable long term than 800, and before I started GLP's it was really very hard to stick to and involved being more or less permanently hungry. I would also face serious health risks were I to regain the weight. I assume from your comment that 800 calories is better than being dead that you might have similar issues.

I would have to disagree with the take a break concept, there is no evidence at all of tolerance to the long term weight loss effects of GLP drugs, with one possible exception, the recent animal study showing much less weight loss from stopping and starting GLP's in mice. It is one study, not replicated and not in humans, but the effect was very strong, and not expected. There have been people on this forum say they have had trouble losing weight after restarting GLP's as well, now a lot of the time that is going to be because they have already lost quite a bit of weight and at that point the GLP drugs are acting to prevent weight regain, but are not enough to cause further weight loss, so effectively a stall. But if the stop start effect is real, that would not help.

Are you on 15mg of tirz? There are metabolic advantages from higher doses that might improve weight loss or allow more calories in at the same rate of weight loss, if you are not already there. And reta is worth considering, the glucagon agonism adds an extra 1 to 200 kcal/day of energy expenditure, and every little bit helps. But it depends a lot on what you have already tried and side effects etc.

 

[wulf00777]

i think 800 calorie intake will be extremely dangerous. Be very careful your body doesn’t start to shut down

I jumped straight to mots c every other day and never used ss31 first

I just had all my organs ultrasounded day before yesterday and will check them again every 25lbs down. I'm in Colombia so any tests are cheap.

 

[wulf00777]

If you've been losing weight or been trying to for longer than 6-12 months, and you're hitting plateus left and right, and lowering your calories down to 800, I strongly strongly recommend you start over.

What I mean by that is, take a break. 30-60 day break from taking your current stack(s) and start taking other peptides OR take a break period to allow your body's tolerance to come back down.

OR

If you haven't been working out or at the very least, walk after your meals, I recommend you do that. Rather than starving your body to the point where now your body is in extreme mode - trying its hardest to keep the calories (hence why it's so hard to lose just a little bit of weight). It think your body is literally dying of starvation. You need to reset that.

Or change up your tactic. Maybe keep the Mots-c if you just started, but take out Tirz and implement reta and/or AOD-9604.

Up you calories to maintenance or a few hundred above maintenance - yes you may regain some weight, but your body will normalize as time goes by and you'll be able to retake the original compounds and lose weight again.

Or at the very least, take walks right after your meals...

I'm suggesting these based off my experience when it comes to long term weight loss, taking different peptides/compounds, and exercising.

I understand every case is relative, but 800 calories is crazy....

Nothing but love for you and I'm fortunate to be here because this forum is full of good people!

Sorry it's just severe metabolic adaptation to years of diets, keto, fasting and very low calorie lifestyle. If you only knew my history with exercise it's even more extreme. If I'm losing at 800 then hell or high water I'm going to keep it rolling.