Lemme Bounce this off the Crowd. . . .

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Sasquatch

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When I started Tirz, it knocked down my cravings pretty substantially. But as time went on, my brain took over.

I know I don't dare over eat. The consequences are BAD!

But the fact I've never lost a pound in 60 years, makes my cravings just as . . . Powerful as ever.

Most folks have had some success and or yoyo. But, I'm serious, it never effing worked. Until. . .well I am loosing weight but I guess, as I've said, I must be thick head or something?

Who still wants a cheeseburger or steak, like any time? 15mg and I still want hostess (gawd awful) apple pies. 🫨
 
How fast did you titrate up? Going up fast in dosage is counter productive.
 
You're doing the hard part, sticking through the mental battle while the biology does its job. That's not thick-headed that's tough as hell . Most folks would cave, you're not. Keep going! I personalty LOVE ZOLLI POPS !!! sugar free. some one advise me on how to stop eating these devilish pops...
 
You might be on the wrong shit. You might just be irredeemable. I kind of doubt that though. Reta completely changed my relationship with food from the very first dose. I haven't tried sema, tirz, cagri, or any of the others we usually talk about here. I don't know what would work for you, but I think that the utility of tirz by itself has reached its limits for you. You may want to consider trying or adding something else. I suspect the collective wisdom of this community might have something to help clarify your thinking.
 
How long you been on and how many vendors have you used? Theres bunk shit a few times a year.... try reta and work ur way up and throw in 1mg of sema. Reta works ur metabolism. I drive for 10 or 12 hours a day, no cardio and lift weights 30 minutes or less a few times a week.... tirz i lost 6lbs and that was it. Reta another 15, over a year... If ur not on calorie def and arent burning calories its very very slow. Folks that were eating 4000 calories and weigh 360 are gonna lose 80lbs. If ur 250 and dont eat much to begin with not so much.....if all else fails look at ur bp, als and alt, triglcyerides, hdl, ldl, glucose and a1c.... if that improved after 6 months its still worth it.
 
Airborne Daddy said:
if all else fails look at ur bp, als and alt, triglcyerides, hdl, ldl, glucose and a1c.... if that improved after 6 months its still worth it.

Exactly. And I love ordering labwork. It's tiring just looking at a scale, waiting for it to move.
 
Calm Logic said:
Exactly. And I love ordering labwork. It's tiring just looking at a scale, waiting for it to move.
1st time lipids were on point in about 5 years and everything else. Labwork i run myself for about a hundred bucks or so vs insurance being billed 700 and charging me 400.
 
r4000 said:
How fast did you titrate up? Going up fast in dosage is counter productive.
I started out on Mounjaro pens. Each had a sheet that gives you the entire titration schedule. So I titrated up according to the EL standard.
 
Camlbacker said:
You might be on the wrong shit. You might just be irredeemable. I kind of doubt that though. Reta completely changed my relationship with food from the very first dose. I haven't tried sema, tirz, cagri, or any of the others we usually talk about here. I don't know what would work for you, but I think that the utility of tirz by itself has reached its limits for you. You may want to consider trying or adding something else. I suspect the collective wisdom of this community might have something to help clarify your thinking.
Tried stacking reta, but I prolly didn't go up high enough. Thinking about Tesamorlin. 😊 Thanks
 
Airborne Daddy said:
- Folks that were eating 4000 calories and weigh 360 are gonna lose 80lbs. If ur 250 and dont eat much to begin with not so much....
This is interesting. I'm around <2000 calories, easily. I am loosing, but Daaaaamb, it's crazy. To be hungry, but don't dare eat (much). My routine is pretty labor intensive. But in the winter it's 4 or 5 hours instead of all day. This ain't lifting weights. This is making hay, running chainsaws, feeding livestock.

Oh yeah, labs are good. I'm due in March. Thanks AD!
 
Sasquatch said:
Tried stacking reta, but I prolly didn't go up high enough. Thinking about Tesamorlin. 😊 Thanks
Read about cagri. Supposedly it KILLS appetite dead for many. I have some and have not tried it because I am finally at goal weight with T and surv but from what I've consistently read on here, if I really want to decimate appetite (and nothing else), cagri would likely very much do the job. ymmv
 
If there's any chance your cravings might be emotional, these peptides may not help. Yes, there's talk and maybe evidence (I haven't followed too closely, someone who reads can correct me) that some of them affect how dopamine is released, and can have some impact on eating that's 100% emotion based and not at all hunger based. But I read a lot of people with BED or other issues with eating to cope that the peptides don't always have the "I don't want food" effect that the "I'm always very hungry" people get relief from with them.

I DO have a history of BED, and they do help me; but I think some of the help may be in my head. I'm careful not to examine that too closely, though.
 
Without knowing a ton more about your history I have no idea if this will be helpful, but I lost the weight by trying and succeeding in preventing extreme hunger and extreme rebound hunger responses by limiting the foods I ate, and not eating anything that might spike blood sugar levels or brain dopamine or whatever biochemical response was occurring to high calorie foods , and in me at least the response after that wears off a few hours later of extreme hunger.

The more your eating issues resemble binge eating disorder or food addiction the more this becomes relevant. I found that eating only low calorific density foods of max 1.5kcal/gram limited hunger a lot, and enabled me to eat as much as I needed to be no longer hungry without too many calories. Which is basically as low fat as is possible , a lot of extremely lean meat, fruit , vegetables, and zero high carb high glycaemic index foods like bread pasta or grains, and a bit of low fat high protein yoghurt and once a day 20 g of dark chocolate as for some weird reason it does not trigger the extreme hunger response. Lots of low fat protein as it is the most filling food there is per calorie. High lean meat soup is excellent.

The advantage of this type of diet is that it is sustainable, healthy, and you can eat as much as you need to eat to not be too hungry, it is almost impossible to eat too many calories of most fruit or vegetables, even if it is mostly sugar, it is mixed with fiber, absorbed slowly and to eat 1000 calories worth of a lot of fruits or veg is 2 kilograms which is actually pretty hard to stuff in even if you do it slowly all day. And you can still eat nearly twice that much and lose weight. You also adjust so that fruit tastes great and you do not miss the high calorie foods as much, but in my case it required total and absolute avoidance of high calorie highly rewarding foods, so far it has worked for 3 years.

I lost the first 70 kg without GLPs as at that time I thought they were too expensive. I kept it off for a year, but it was very hard, I was still hungry a lot of the time and almost never full and metabolic adaptation required an intake of about 1600-1800 kcal/day to maintain weight.

I discovered that prescription ozempic was not super expensive in Aus at low doses and tried that for a year and it helped but was nauseating, but it did make it a bit easier to not be so hungry. Then I discovered this forum , switched to 15mg tirzepatide , added in 5mg of retatrutide as well after a while when I was still a bit hungry all the time. They made a big difference, feeling full after small meals of 300 kcal or so , much less cravings for unhealthy food. And I ended up gradually losing another 8 kg over the past 7 months. I do not think I would have been able to get rid of the weight or keep it off without both the GLP's and the diet strategy. I had previously got to normal bmi range but had never been able to stay there for more than a couple of years, but then I did not fully understand my hunger responses to different foods, and there were no glp's. I think the strategy of avoiding all high calorific density foods works for me and my understanding of physiology suggests it should be one of the easiest ways to tolerate lowered calorie intake long term, with the least amount of hunger. But I think the total avoidance of rich foods is needed to reset your sense of taste, so that less rich foods taste better over time, and to prevent triggering of extreme rebound hunger if you are sensitive to that problem. In some ways it is really hard to stick to , requiring complete avoidance of a lot of popular foods , but in others it is the easiest, where you can eat as much as you need to and still lose weight. And GLP's definitely help make it easier.
 
randompersonrandom said:
If there's any chance your cravings might be emotional, these peptides may not help. Yes, there's talk and maybe evidence (I haven't followed too closely, someone who reads can correct me) that some of them affect how dopamine is released, and can have some impact on eating that's 100% emotion based and not at all hunger based. But I read a lot of people with BED or other issues with eating to cope that the peptides don't always have the "I don't want food" effect that the "I'm always very hungry" people get relief from with them.

I DO have a history of BED, and they do help me; but I think some of the help may be in my head. I'm careful not to examine that too closely, though.
I was gonna DM, but this could help someone else, maybe?

I been on Phenofibrate, forever. (Cholesterol med) Recently studied to have side-effects like 'over-emotional.' We tear up at the stupidest things. And used to wonder why?

This could, be fighting the effects of another chemical. I won't find out unless I stop one or the other. (Won't be for awhile) I just don't think it's BED. Thanks for that rabbit hole. 😁 I dunno? I'm still 'highly functional.' Can't dwell too long. I got stuff to do. BTW, that (stuff to do) could be my saving grace. 😇 Thanks Rando!
 
Sasquatch said:
I was gonna DM, but this could help someone else, maybe?

I been on Phenofibrate, forever. (Cholesterol med) Recently studied to have side-effects like 'over-emotional.' We tear up at the stupidest things. And used to wonder why?

This could, be fighting the effects of another chemical. I won't find out unless I stop one or the other. (Won't be for awhile) I just don't think it's BED. Thanks for that rabbit hole. 😁 I dunno? I'm still 'highly functional.' Can't dwell too long. I got stuff to do. BTW, that (stuff to do) could be my saving grace. 😇 Thanks Rando!

happy to drop something that might be useful to you or anyone else!
 
Sasquatch said:
Tried stacking reta, but I prolly didn't go up high enough. Thinking about Tesamorlin. 😊 Thanks

I looked into Tesa, but I think that tesa is probably better when you're closer to goal. Not sure if you're already at goal. But I also read that it can increase appetite and is really more about body fat redistribution and not weight loss. So soon as I read the thing about increased appetite, I was like, yeah not right now....🤣

Since you had good success with appetite supression on tirzepatide, you could always go above 15mg. I'm taking like 17 or 18mg depending on the week and it's been fine. There are lots of anectdotal accounts of people taking 20mg and having good success. I'm stacking tirzepatide with a low dose of semaglutide since early December and that has wiped out mental thoughts about food. I actually like how sema feelz on shot day and the few days after. Definitely different than tirz.
 
Grogu said:
I looked into Tesa, but I think that tesa is probably better when you're closer to goal. Not sure if you're already at goal. But I also read that it can increase appetite and is really more about body fat redistribution and not weight loss. So soon as I read the thing about increased appetite, I was like, yeah not right now....🤣

Since you had good success with appetite supression on tirzepatide, you could always go above 15mg. I'm taking like 17 or 18mg depending on the week and it's been fine. There are lots of anectdotal accounts of people taking 20mg and having good success. I'm stacking tirzepatide with a low dose of semaglutide since early December and that has wiped out mental thoughts about food. I actually like how sema feelz on shot day and the few days after. Definitely different than tirz.
I looked in to Cagri too. And even Sema. Cuz it's cheap. But there's something to be said for simplicity. That said, there's a real possibility Reta will replace Tirz, once it gets it's pedigree from big doctor whats-his-nutz. It's stupid how slow the wheels of "grandpa's medicine" turns. By the time they release reta the early adopters will have moved on. That's not new I guess.
 
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