积极的副作用

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ZippityDooDah

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我很想知道有多少人服用替泽帕肽后体验到了积极的副作用?

自从开始服用以来,我几乎戒了酒,感觉自己也快要戒烟了,耳鸣似乎略有改善,而且我明显感觉我的注意力缺陷多动症(ADHD)症状也有所改善。

当然,体重减轻对很多方面都有积极的副作用,包括缓解疼痛、提高灵活性,以及​​让日常活动变得更加轻松。但这种药物的作用肯定不止于对血糖和体重的影响。
 
天哪!我竟然完全停用了多动症和类风湿性关节炎的药!!感觉棒极了,注意力也集中多了。自从2022年12月开始服用这些药以来,我的生活发生了好多积极的变化。其实我有点害怕达到目标体重后,不得不减少药量,然后可能就减不掉那部分体重了。
 
我焦急地等待着尼古丁和酒精的渴望消退;我真心希望随着剂量的增加,情况会好转一些。我已经减少了摄入量,但这都是经过深思熟虑后做出的决定。以往的经验是,我只有在戒酒后才会减肥。
 
ZippityDooDah said:
I'm curious how many people have experienced positive side-effects on tirzepatide?

Since starting I have pretty much given up alcohol, I feel like I'm almost ready to quit smoking, my tinnitus seems to have improved slightly, and I definitely feel like it's improved my ADHD.

Obviously the weight loss has had a positive side-effect on many aspects including aches and pains, flexibility, and just being easier to do every day things, but there's definitely more to this med than the impacts on blood sugar and weight.
When did you notice the declined desire for alcohol? What dose are you at?
 
All of the above!

Definitely lowered cravings of all kinds- I used to battle sugar craving like an addict.

Now I just get what I think is normal taste cravings when I’m actually hungry.

I’m ok with 1 drink if we are out to dinner (vs what used to be a couple a night every weekend).

I have a ton more focus and energy through my day.

I feel like my skin feels softer and that my face looks a little younger? Maybe just wishful thinking there.

I try to focus on all these non scale victories to keep me going when I feel like I have so far to go weight wise.
 
JayEm79 said:
I’m anxiously awaiting for the nicotine & alcohol cravings to subside; I really hope as increase my dose, it’ll be easier. I’ve decreased my consumption but it’s through very conscientious decision making. Historically, I’ve only ever lost weight when I’ve quit drinking.
It hasn’t magically taken away my love of wine either but the acid reflux was almost unbearable so that may be what curbs my intake the
 
It’s the acid reflux for me too! Like the moment I take a sip. I don’t even know how it’s feasible. I had to prop my whole body up to sleep like when I was pregnant and I already take omeprazole. Oof. That’s curbed my intake even if my love of wine including the taste hasn’t gone away at all.
 
JayEm79 said:
When did you notice the declined desire for alcohol? What dose are you at?
It started about my third week on 2.5mg MJ pens. My nightly extra large cocktail ended up being poured down the drain after just a few sips and then sitting on the table looking abandoned several times; by the following week I just stopped making it.

On top of that, I had two shots of bourbon at the neighbor's probably my 3rd week into 5mg SAF and I literally lost the next 24 hours to nausea (not hangover nausea either, 500x worse!). Since then I've only had one beer here or there, and even then they didn't agree with me very well. the TZ must alter how my liver processes the sugars and so I just stopped tempting fate.
 
ZippityDooDah said:
It started about my third week on 2.5mg MJ pens. My nightly extra large cocktail ended up being poured down the drain after just a few sips and then sitting on the table looking abandoned several times; by the following week I just stopped making it.

On top of that, I had two shots of bourbon at the neighbor's probably my 3rd week into 5mg SAF and I literally lost the next 24 hours to nausea (not hangover nausea either, 500x worse!). Since then I've only had one beer here or there, and even then they didn't agree with me very well. the TZ must alter how my liver processes the sugars and so I just stopped tempting fate.
Oh, I 100% feel like shit after I drink while on Tirz. I’ve decreased my consumption from a bottle a night down to once a week now but my brain just can’t let go of the once a week. I just took my first 5mg (also SAF) this week. Fingers crossed the higher dose helps me get over this mental hump.
 
I have similar reduction in desire for alcohol as described above. Another weird one: I used to have a habit of biting my nails which has gone away. On the negative side, I used to get really excited about various things and now I feel like I'm faking excitement sometimes. Obviously this could be about food and cooking a meal but other things too. For example, going out to a concert or travel now seems like a hassle rather than something I'm really excited about. Not sure if this is just a cycle thing that will change or if it is the Tirzapatide.
 
I never really bit my nails, but If they got a little long I may have partaken.

Completely gone.

Also when I first started my libido went into the tank hard.
 
I am on 2.5mg weekly but micro dosing. Beer just didn't taste the same so I have stopped drinking. I drank a higher avb beer and got the biggest headache after it. (I also took MOTS-C) I am sad because I make my own beer at home and won't enjoy it like before.
 
Tidalwave said:
Although I am not losing weight, my blood sugar has stopped spiking and has been stable .

There is some evidence that GLP-1 agonists may help reduce cardiovascular risk factors like high blood pressure, high cholesterol, and inflammation.

These drugs may work by improving insulin sensitivity and reducing blood glucose levels, which can reduce the risk of cardiovascular disease.

Additionally, they may help reduce atherosclerosis, which is the build-up of plaque in the arteries that can lead to heart disease. And some studies have even suggested that GLP-1 agonists may reduce the risk of stroke. Of course, more research is needed to confirm these findings.
 
Tidalwave said:
There is some evidence that GLP-1 agonists may help reduce cardiovascular risk factors like high blood pressure, high cholesterol, and inflammation.

These drugs may work by improving insulin sensitivity and reducing blood glucose levels, which can reduce the risk of cardiovascular disease.

Additionally, they may help reduce atherosclerosis, which is the build-up of plaque in the arteries that can lead to heart disease. And some studies have even suggested that GLP-1 agonists may reduce the risk of stroke. Of course, more research is needed to confirm these findings.
Before this med I was 155 BP constantly.

130 now. Also 30lbs down
 
doughnutcat said:
Before this med I was 155 BP constantly.

130 now. Also 30lbs down

doughnutcat said:
Before this med I was 155 BP constantly.

130 now. Also 30lbs down

Interestingly the SURMOUNT-2 studies expressed some concerns about the effect of tirzepatide on blood pressure, including the potential for an unsafe drop in blood pressure for people with already low blood pressure, as well as dizziness and fainting.
 
doughnutcat said:
Before this med I was 155 BP constantly.

130 now. Also 30lbs down
What's crazy is that the stupid medical establishment still considers 130 systolic as too high.

When I took paramedic training back in a previous century, the common standard for "normal" systolic BP was 100+a persons age and <100 diastolic. It was only considered high if systolic was more then 10% above the norm or if diastolic was >100. Then they lowered the hypertension threshold to 140 systolic, and when they couldn't get enough people paying for blood pressure meds they came up with this stage 1/stage 2 BS and lowered it again to 130.
 
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