How soon to stop wolverine blend before surgery?

[Gr33dyOctopus]

Surgery is on Feb 9th, and i took my last glp1 shot on the 22nd. I could take it farther apparently but rather not take any risks with that if i can help it.

I have Bpc/tb500 that i i am running daily, only two or three weeks in, but want to test the KLOW80. before my surgery as i would.like to use that mix in the healing process post surgery.

Going to reconstitute a bottle of Klow today, how long can i theoretically safely run it till my operation, and how soon can i tart it up after? Dont want my dr to know im taking these things, was hard enough to find a pcp in the first place, and i dont think she would be cool with me takong Chinese gray.

 

[Jfrick11]

Surgery is on Feb 9th, and i took my last glp1 shot on the 22nd. I could take it farther apparently but rather not take any risks with that if i can help it.

I have Bpc/tb500 that i i am running daily, only two or three weeks in, but want to test the KLOW80. before my surgery as i would.like to use that mix in the healing process post surgery.

Going to reconstitute a bottle of Klow today, how long can i theoretically safely run it till my operation, and how soon can i tart it up after? Dont want my dr to know im taking these things, was hard enough to find a pcp in the first place, and i dont think she would be cool with me takong Chinese gray.

Yeah… this is one of those posts where the red flags are waving pretty hard.

This is exactly the kind of situation where your surgeon and anesthesiologist need to know what you’re taking.

These aren’t just supplements (which are also imprtsnt to disclose for many of the same reasons. BPC-157, TB-500, KPv, copper and GLP-1s can all affect things like inflammation, digestion, bleeding risk, wound healing, blood pressure, and how anesthesia works. Asking a forum for timing advice while intentionally hiding this from the doctor who is about to operate on you is no bueno.

Doctors don’t care about “Chinese gray” from a moral standpoint..... they care because: they need to prevent surgical complications, they need to manage anesthesia safely, they need to know what could interfere with healing or clotting.

If something goes wrong and they don’t know what you’ve been using, that puts you at much higher risk and makes it harder for them to help you.

It’s understandable to worry about being judged or losing a PCP, but this is your health and your surgery.

This is one of those moments where full disclosure matters more than forum opinions. A quick, honest conversation with your surgeon is far safer than trying to time peptides based on crowd advice.

At minimum, this is a question for your surgeon/anesthesia team..... not strangers on the internet.

 

[BigGuy73]

Here is where I have to be the asshole and disagree. While ideally you should be able to freely admit to your surgeon about everything, the surgeon may report this to your insurance that may decide against paying for your surgery because you admitted to taking unapproved compounds that could complicate things. It sucks but this is America where money is the bottom line, not your healthcare

 

[Dos-Dox]

I’d personally (as-in only what I would do for myself if it was me ) base it off of 4-5 half lives and then go conservative and add some extra time to it (like an extra week for non-GLPs). Assuming your TB-500 in your blend is really TB4, both it and the BPC have really short half lives.

Use your best judgement (it’s your life and health) but it’s not really worth the risk to push it immediately before a surgery. You’re not going to lose a lot of ground with any protocols you’re running by being conservative and waiting until after your procedure to start.

 

[Chili777]

The half-life of most peptides is not all that long. Reta and Sema are some of the longest at 6 and 7 days, respectively.

Of all the peptides in KLOW, BPC has the longest half-life and that's only 3 hours. The rest are shorter. I'd give it 3-5 days and call it good.

 

[MsGizmo]

Surgery is on Feb 9th, and i took my last glp1 shot on the 22nd. I could take it farther apparently but rather not take any risks with that if i can help it.

I have Bpc/tb500 that i i am running daily, only two or three weeks in, but want to test the KLOW80. before my surgery as i would.like to use that mix in the healing process post surgery.

Going to reconstitute a bottle of Klow today, how long can i theoretically safely run it till my operation, and how soon can i tart it up after? Dont want my dr to know im taking these things, was hard enough to find a pcp in the first place, and i dont think she would be cool with me takong Chinese gray.

I'm in the same boat. I have a medical thing coming up in April and was told to stop ozempic 2 weeks before. I am thinking that I will stop everything at that same two week mark just to be on the safe side. I will spend those 2 weeks redoing the pre-op prep diet I was on before having my vertical sleeve surgery to ensure my weight loss doesn't stop. Not fun, but not terrible either.

For those that don't know .. its basically a protein shake only diet.

 

[Gr33dyOctopus]

Alright. I definitely am not telling my dr about anything else other than the completely legal tirz compound that im on. Im cutting off all pinning untilnsurgery day which is 16 days away, pretty sure ill be fine. The gallbladder surgeon said a 2 weeks to a month is usual for glp1s, and over on reddit i have a similar post and theres a guys that said that they went thru the surgery and never missed a shot. Ill feel safe having an 18 day time since my last pin. Totally cool with that. I dont want to risk all the crazy shit that aspirating food into my lungs and all the other bad shit can come to.

 

[igottapee]

Alright. I definitely am not telling my dr about anything else other than the completely legal tirz compound that im on. Im cutting off all pinning untilnsurgery day which is 16 days away, pretty sure ill be fine. The gallbladder surgeon said a 2 weeks to a month is usual for glp1s, and over on reddit i have a similar post and theres a guys that said that they went thru the surgery and never missed a shot. Ill feel safe having an 18 day time since my last pin. Totally cool with that. I dont want to risk all the crazy shit that aspirating food into my lungs and all the other bad shit can come to.

you should be good as long as you follow eating(non eating) orders prior to surgery.

 

[Gr33dyOctopus]

I'm in the same boat. I have a medical thing coming up in April and was told to stop ozempic 2 weeks before. I am thinking that I will stop everything at that same two week mark just to be on the safe side. I will spend those 2 weeks redoing the pre-op prep diet I was on before having my vertical sleeve surgery to ensure my weight loss doesn't stop. Not fun, but not terrible either.

For those that don't know .. its basically a protein shake only diet.

What an awesome way to lose weight!

you should be good as long as you follow eating(non eating) orders prior to surgery.

Thank you! I totally agree, but I've never ever had a surgery before, and the surgeon rattled off all kinds of extremely unpleasant shit. Definitely upon reflection ill.do everything I can to be sure its successful and jump through any hoops offered by the medical team!!!

 

[igottapee]

What an awesome way to lose weight!

Thank you! I totally agree, but I've never ever had a surgery before, and the surgeon rattled off all kinds of extremely unpleasant shit. Definitely upon reflection ill.do everything I can to be sure its successful and jump through any hoops offered by the medical team!!!

oh, I get it! I had both knees replaced a couple of years ago, lol. My kiddo works on the liver transplant team at her hospital and yes, you want to follow their orders!

 

[Abrakebabra]

I'm having lumbar surgery on 10th Feb and had a pre admission call from a nurse this morning. Told her I was on Tirz and she said that was fine and I didn't need to stop taking it. For context that's a private healthcare provider in the UK - so not sure if guidance differs, and certainly not seeking to give you advice, was just what I was told only an hour or so ago.

 

[ZippityDooDah]

I'm having lumbar surgery on 10th Feb and had a pre admission call from a nurse this morning. Told her I was on Tirz and she said that was fine and I didn't need to stop taking it. For context that's a private healthcare provider in the UK - so not sure if guidance differs, and certainly not seeking to give you advice, was just what I was told only an hour or so ago.

Presuming you are going to be under anesthesia, that is absolutely incorrect and you need to speak to your surgeon or anesthesiologist about this asap .

GLP-1s slow digestion. You are told to not to eat prior to surgery to ensure full digestion of any foods so there is nothing in your system that could aspirate.

Everyone I know that has had any kind of surgery where they would be sedated has been told to stop their GLP-1 at least two weeks prior. It may be out of an abundance of caution, but it's probably better than drowning on your own stomach contents.

 

[Abrakebabra]

Presuming you are going to be under anesthesia, that is absolutely incorrect and you need to speak to your surgeon or anesthesiologist about this asap .

GLP-1s slow digestion. You are told to not to eat prior to surgery to ensure full digestion of any foods so there is nothing in your system that could aspirate.

Everyone I know that has had any kind of surgery where they would be sedated has been told to stop their GLP-1 at least two weeks prior. It may be out of an abundance of caution, but it's probably better than drowning on your own stomach contents.

I was surprised as well - as it was something I was going to make sure I raised. I was told that the guidance has been updated that they now no longer need to be stopped. I certainly wouldn't play fast and loose with the medical advice and am following the instructions they've given me.

Having done a bit of googling it does seem like new guidance was released in 2025 that suggests they are safe to continue but the medical team should be aware so any risk can be managed.

The British consensus statement for the relevant medical bodies (including the Royal College of Anaesthetists) can be found here. A statement by the by the equivalent American bodies is referenced here. Both of those seem to confirm that you can continue - but risk should be managed.

So no question I'm sure people have been advised previously that they have to stop, but I'm going to follow the advice I've been given by my medical team which seems to be following the most up to date recommendations. Clearly I would never advocate for anyone to ever go against any medical advice they were given.

 

[RubbaDubba1]

I'm having a Hernia surgery and stopped everything 3 weeks ago (which sux) this will be my 3rd surgery while on a GLP-1. Every time it was 2 weeks they told me, but I do 3 out of precaution with the GLP-1 and the other peptides.

 

[Dos-Dox]

Hey, @Gr33dyOctopus , I know you already stopped your protocol, but I just came across this and thought I’d pass it along for your information.

(I wish this person had given the disclaimer about using talk to text at the start because as I was reading it, I was thinking “no way this person has credibility if he or she is using things like ‘intern’ instead of ‘in turn’.” )

https://www.reddit.com/r/bpc_157/s/g0cEeEj6vW