Has anyone here gotten any results from GHK-CU?

[Sparky757]

I’m a couple months in on GHK and I’ve seen a noticeable difference in fine lines and overall complexion, however not much with my hair. After doing more reading it sounds like it helps with hair but it’s more directed for skin. AHK-cu is supposed to be more for hair growth by stimulating dermal cells.

I’m just using GHK on my face and neck and just started AHK about a week ago, for my hair.

Edit: I should have added that these are cosmetic GHK and AHK.

I also do injectable GHK. Cycling on and off.

I'm in a bit of a rabbit hole recently about GHK-Cu and its effects on skin. Specifically, I'm trying to get my head around the correct delivery method: subcutaneous, topical, or microneedling. I found a study that says topical barely gets anything through the stratum corneum but that microneedling does pass that barrier. That study is here.

I'm not convinced subcutaneous GHK-Cu is the answer. This is because I make comparisons with vitamin C (ascorbic acid). Study after study shows that oral ingestion of even very high amounts of vitC does not come into the ballpark for concentrations of the molecule in the skin when compared to topical application (especially formulations such as Skinceuticals' ferulic acid/tocopherol formula that just recently went off patent). In contrast with GHK-Cu, vitC does get absorbed with low enough pH.

The concentration in the skin itself is where it counts. I am skeptical that pinning GHK-Cu achieves a high enough concentration where it counts to be doing what we're hoping it's doing. We think we're solving for the "can't get past the skin barrier" problem with pinning, but pinning doesn't solve any problem other than getting large molecules past the digestive tract. Are there any studies that are on subQ GHK-Cu and skin specifically? I can't find any.

 

[cheaperseeker]

GHK-Cu helps with more than just skin. Immunity, antioxidant, anti-inflammation, wound healing. Pin for the systemic effects and apply topically/MN to treat specific areas of skin/hair.

 

[50ShadesGreyMarket]

I'm in a bit of a rabbit hole recently about GHK-Cu and its effects on skin. Specifically, I'm trying to get my head around the correct delivery method: subcutaneous, topical, or microneedling. I found a study that says topical barely gets anything through the stratum corneum but that microneedling does pass that barrier. That study is here .

I'm not convinced subcutaneous GHK-Cu is the answer. This is because I make comparisons with vitamin C (ascorbic acid). Study after study shows that oral ingestion of even very high amounts of vitC does not come into the ballpark for concentrations of the molecule in the skin when compared to topical application (especially formulations such as Skinceuticals' ferulic acid/tocopherol formula that just recently went off patent). In contrast with GHK-Cu, vitC does get absorbed with low enough pH.

The concentration in the skin itself is where it counts. I am skeptical that pinning GHK-Cu achieves a high enough concentration where it counts to be doing what we're hoping it's doing. We think we're solving for the "can't get past the skin barrier" problem with pinning, but pinning doesn't solve any problem other than getting large molecules past the digestive tract. Are there any studies that are on subQ GHK-Cu and skin specifically? I can't find any.

You seem to know your stuff but if anyone is new to topical peptides make sure every single thing is sterile af and start at .25mm - I have a whole bunch of serums I use as well as stem cells. Buy a professional grade (I have a Dr Pen Ultima M8) and never re-use needles - they come in individually sealed medical-grade packaging. Try it out on another part of your body first with different cartridges. Clean your face with alcohol very well just before you start, right after wiping off the numbing cream. WEAR GLOVES. Any bacteria that touches your face can cause an infection because you’re piercing the skin’s protective barrier. I’ve used Asterwood Copper Peptides w/hyaluronic acid and had good results, you can buy it online. For the days of healing, you must keep your face clean and well moisturized, don’t use hot water or steam. Treat your face like a burn until it heals then treat it like a newborn baby. The more times you do it, the tougher the skin gets to needle (that’s collagen!). I had it done professionally 10-15 times before I ever did it myself because I didn’t want to make a mistake. It’s good to do it 3 times spaced a month apart as it takes about 12 weeks to really notice a dramatic difference. TAKE BEFORE AND AFTER PHOTOS! As your skin is repairing itself you may not notice changes but if you compare the 12 week pics to what you started with, zooming in around your eyes, jawline, forehead, etc you’ll notice a night and day difference.

If you decide to get it done professionally first do your research and see if a place offers stem cells. It cut my healing time from 7-10 days of raw skin down to 3-5 and the redness went away much quicker. I’ll attach a pic of the first time I got it done, I bled like crazy because my skin was so thick that she had to dial it up to 1mm. They wipe the blood around with the stem cells because it helps with the healing, similar concept to Vampire facial with Platelet-Rich Plasma.

I pin 1mg GHK-Cu nearly daily and my skin is extremely soft. If I was trapped on an island and could only have 1 peptide, it would probably be GHK-Cu.

I use a lot of other things as well as vitamin C, too!

 

[50ShadesGreyMarket]

Skin n hair wise?

Ran 2 cycles before,

1st at 3 mg/day, 2 months, 1 nmonth break

2nd at 5mg/day, 2 months, 1 month break

Reconstituted with Bac water first cycle and PBS second cycle. 0 results

Before I waste my money again, have any of u actually see a noticeable improvement when u look at the mirror or the camera

gotten to the point where i m assuming people hyping this up are paid

Keep in mind everyone responds differently to different treatments and different people are just, well, different.

You and I use different doses, as well. I do about 1mg per day of just GHK-Cu for months then cycle GLOW 50/10/10 at 2mg/day for 5 days on, 2 days off for a total of 8 weeks straight. I do this a couple of times a year. I use a much lower dosage and when I’m not doing the GLOW protocol I pin GHK-Cu almost every single day.

Unless someone is advertising a specific company or brand then I don’t see why they would benefit from the hype, it’s not expensive and we’re all here to avoid the costs of doctor shopping and big pharma. I’ve been on various peptides for over a decade, my goal is to “naturally” preserve my body as much as reasonably possible because I don’t plan to go under the knife.

“An ounce of prevention is worth a pound of cure.”

 

[Incognitodoberman]

I'm in a bit of a rabbit hole recently about GHK-Cu and its effects on skin. Specifically, I'm trying to get my head around the correct delivery method: subcutaneous, topical, or microneedling. I found a study that says topical barely gets anything through the stratum corneum but that microneedling does pass that barrier. That study is here .

I'm not convinced subcutaneous GHK-Cu is the answer. This is because I make comparisons with vitamin C (ascorbic acid). Study after study shows that oral ingestion of even very high amounts of vitC does not come into the ballpark for concentrations of the molecule in the skin when compared to topical application (especially formulations such as Skinceuticals' ferulic acid/tocopherol formula that just recently went off patent). In contrast with GHK-Cu, vitC does get absorbed with low enough pH.

The concentration in the skin itself is where it counts. I am skeptical that pinning GHK-Cu achieves a high enough concentration where it counts to be doing what we're hoping it's doing. We think we're solving for the "can't get past the skin barrier" problem with pinning, but pinning doesn't solve any problem other than getting large molecules past the digestive tract. Are there any studies that are on subQ GHK-Cu and skin specifically? I can't find any.

I’m sure it’s going to vary from person to person, how long you do it, how much you use, topical or injectable etc.

I’ve seen nice results for the short amount of time that I’ve been doing it. I apply cosmetic to my face 2x a day and micro needle it about once a week.

My micro needle face roller does not give the same effect as that member pic above this post. Nor would I want it to. It doesn’t burn and I don’t wear gloves, however my face and hands are very clean.

I inject every other month, every day. Then cycle off.

Here’s a study I have read a few times.

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[50ShadesGreyMarket]

I’m sure it’s going to vary from person to person, how long you do it, how much you use, topical or injectable etc.

I’ve seen nice results for the short amount of time that I’ve been doing it. I apply cosmetic to my face 2x a day and micro needle it about once a week.

My micro needle face roller does not give the same effect as that member pic above this post. Nor would I want it to. It doesn’t burn and I don’t wear gloves, however my face and hands are very clean.

I inject every other month, every day. Then cycle off.

Here’s a study I have read a few times.

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A dermaroller is far less intense so you shouldn’t bleed much, if at all. Microneedling works like a tattoo gun but with serum instead of ink. The depth and speed of the device that causes the bleeding you see in my pic requires prescription-strength numbing cream and a Xanax.

 

[Incognitodoberman]

A dermaroller is far less intense so you shouldn’t bleed much, if at all. Microneedling works like a tattoo gun but with serum instead of ink. The depth and speed of the device that causes the bleeding you see in my pic requires prescription-strength numbing cream and a Xanax.

A Xanax? Like singular? Maybe two or three

 

[50ShadesGreyMarket]

A Xanax? Like singular? Maybe two or three

.5 mg can last me a 9 hr flight in Business Class

 

[BLASIUS]

I am almost at the end of my first cycle (32 days on a total of 40) of GLOW using 2mg of GHK-Cu per day.

I have a nice feeling touching my skyn that I never had before, not easy to explain.

I took some pictures of my skin the day I started and comparing with the current ones it looks that something has changed. Some spots disappered and the wrinkles looks to be less deep.

Attached are the pictures of my right hand before and now.

make up your own mind.

Update;

Today is day 36/40, I took a new picture of my right hand, and I noticed something interesting:

Spot 1 completely disappered

Spot 2 looks to be going to disappear too.

Maybe I made a not good quality picture at the beginning (wrong lights basically), so maybe I am a little bit too much optimistic about the results .... let's wait the final shot and if the spot 2 will definetively disappear I can say that GLOW blend is great.

 

[lemon lady]

Keep in mind everyone responds differently to different treatments and different people are just, well, different.

You and I use different doses, as well. I do about 1mg per day of just GHK-Cu for months then cycle GLOW 50/10/10 at 2mg/day for 5 days on, 2 days off for a total of 8 weeks straight. I do this a couple of times a year. I use a much lower dosage and when I’m not doing the GLOW protocol I pin GHK-Cu almost every single day.

Unless someone is advertising a specific company or brand then I don’t see why they would benefit from the hype, it’s not expensive and we’re all here to avoid the costs of doctor shopping and big pharma. I’ve been on various peptides for over a decade, my goal is to “naturally” preserve my body as much as reasonably possible because I don’t plan to go under the knife.

“An ounce of prevention is worth a pound of cure.”

So you take GHK-Cu all year round with no break?

 

[lemon lady]

GHK-Cu helps with more than just skin. Immunity, antioxidant, anti-inflammation, wound healing. Pin for the systemic effects and apply topically/MN to treat specific areas of skin/hair.

Would taking it topically and subq cause the 'copper uglies' where it has the opposite effect and depletes your colagen?

 

[cheaperseeker]

Would taking it topically and subq cause the 'copper uglies' where it has the opposite effect and depletes your colagen?

I believe this happens because copper and zinc use the same receptors, so if there is too much copper, it will crowd out the zinc at the receptors. Taking a zinc supplement should prevent this.

I'm no doctor, so your best to do your own research on this.

 

[Incognitodoberman]

So you take GHK-Cu all year round with no break?

You can use cosmetic GHK everyday but you should be cycling on and off of injectable.

 

[PablinhoDoFavela]

I look younger now than I did a year ago before I started. I started at about the same time I started taking a GLP-1. I was trying to get ahead of possible loose skin and the aging look that weight loss can cause. I don't have any loose skin after losing around 60-70 pounds, and am 54 years old. My hair is much thicker than it was before I even began to lose weight.

However, I also did a lot of other things at the same time to try to prevent sagging:

Ran KPV with GHK-Cu, glutathione, Athena, zinc, and vitamin c. I lost less than two pounds a week, exercised, took multivitamins with extra hair, skin and nails vitamins and minerals. Ate healthy, ate an appropriate amount of protein and added an amino acid/collagen supplement.

So I guess I can't say that it was just the GHK-Cu, and truly, most of us who are using it are also using other peptides/supplements at the same time and making other health related changes.

But at about 80 dollars a year, what have I really got to lose? I'm going to keep doing the same things.

how much u inject per day?

 

[PablinhoDoFavela]

Bacteriostatic water works just fine.

will order it, any tips for starters? and what results should i expect?

 

[FlowerFairy]

I tried dm'ing you but apparently I still don't have that benefit?

Anyways, I am currently on an Adderall prescription so Ascorbic Acid would be detrimental for me. Can gluta still be reconstituted with anything else?

I’m on adderall and I take glutathione reconned with vitamin C. Adderall is in the morning, glutathione w/vitamin C at night. No issues due to the separation.

 

[FlowerFairy]

So you take GHK-Cu all year round with no break?

I’ve been on it for 6 months without a break. Between that and the glutathione, skin is improved, less crepey texture on my neck and décolletage. Hair is growing faster than it has in YEARS. It’s halfway down my back, even with losing weight.

 

[PablinhoDoFavela]

I’m on adderall and I take glutathione reconned with vitamin C. Adderall is in the morning, glutathione w/vitamin C at night. No issues due to the separation.

idk man id rather not risk it especially bc id be injecting straight to my body so idk how long would the vitamin c remain in my body

 

[Ru272]

I'm on my 2nd cycle of KLOW, I LOVE the effects, my skin is glowing and I hardly need to wear foundation. After this cycle i'm going to just do GHK-CU/KPV, no plans to ever stop

That’s what I do now… GHKcu with kpv… love it

 

[FlowerFairy]

idk man id rather not risk it especially bc id be injecting straight to my body so idk how long would the vitamin c remain in my body

It’s a personal preference. I don’t notice a difference in the Adderall response, but this doc still has me way underdosed (every mh doc starts me over on my add meds; I was on 40 mg for years, but recently they insist on starting me at 10 mg and sllloooowwwwwwwly increase it).