Had surgery to fuse bones- peptide recommendations for any/all aspects of this, including to minimize harm of laying in bed for months?

[lavender]

I had bunion surgery where they essentially are trying to fuse two of my foot bones together, and I'll have the same surgery on the other foot in two months, as soon as I can use the first foot, lol.

Looking for peptide recommendations for helping the fusion if that exists, general body/systemic support, and support to minimize harm of laying in bed for almost six months straight? Looking into SLU-PP-322 for that last one, I am new to the world of "exercise numerics" but very interested. Already taking BPC157/TB400 (and reta, unrelated).

TYIA, hope everyone is well.

 

[retarequired]

I would avoid SLU-PP-322, it doesn't dissolve in water and the workaround is likely unsafe to inject.

Best of luck with your healing journey!

 

[lavender]

I would avoid SLU-PP-322, it doesn't dissolve in water and the workaround is likely unsafe to inject.

Best of luck with your healing journey!

Oh good to know, ty!! I guess I'll keep looking in that arena.

 

[skeptick]

I had bunion surgery where they essentially are trying to fuse two of my foot bones together, and I'll have the same surgery on the other foot in two months, as soon as I can use the first foot, lol.

Looking for peptide recommendations for helping the fusion if that exists, general body/systemic support, and support to minimize harm of laying in bed for almost six months straight? Looking into SLU-PP-322 for that last one, I am new to the world of "exercise numerics" but very interested. Already taking BPC157/TB400 (and reta, unrelated).

TYIA, hope everyone is well.

Still too new to know enough about recommending which peptides, dosing, etc but as somebody who laid in bed in traction for several months after a logging accident. Had some discs fused and some kinda spring-loaded device installed. Took a long time to mostly heal from that surgery, worst of pain is past but decrease of range of motion nearly as bad. Isotonic exercises can be your friend. Keep all you can of your upper body strength. You'll need it for to power your wheelchair and/or crutches. Go easy on the pain meds as kicking that habit is a mother freaking bitch. Much worse that kicking coke... Beware the respitory therapist. Happy healing...

 

[yrrdead]

I'd add KPV into the stack from a systemic healing standpoint. You could even argue the whole KLOW stack wouldn't be terrible.

On a non peptide front. Look into NMES/TENS units. Your insurance might even cover a unit. My buddy got a nice one basically like a rental from his insurance for 6 months. Relatively simple to use.

On chemical assistance , most of the things I could think of that are anabolic/muscle preserving also have the most side effects. Which generally I won't recommend. You can again talk to your Dr specifically about this and see if he/she recommends anything. Even if the prescription wouldn't be covered that gives you an avenue to look into.

 

[exploitedworkerbee]

I had bunion surgery where they essentially are trying to fuse two of my foot bones together, and I'll have the same surgery on the other foot in two months, as soon as I can use the first foot, lol.

Looking for peptide recommendations for helping the fusion if that exists, general body/systemic support, and support to minimize harm of laying in bed for almost six months straight? Looking into SLU-PP-322 for that last one, I am new to the world of "exercise numerics" but very interested. Already taking BPC157/TB400 (and reta, unrelated).

TYIA, hope everyone is well.

BPC/TB4 to help the soft tissue healing, and hgh or a secretagogue to help you hold onto what muscle you can while you’re immobile. I wouldn’t start the gh/secretagogue until 1+ months post-op because the water retention probably isn’t great for the swelling you’re going to have. IMO slu-pp is all hype at best, and potentially dangerous, wouldn’t touch it.

I had a fusion of the big toe last year so am aware of what you’re embarking on, good luck.

 

[GrandmaJ]

Not a pep but don't sleep on magnesium. I had a non-union broken femur that didn't heal for 18 months. Turned out my magnesium levels were low. Once I started supplementing, fused in 6 weeks. It's cheap to supplement. Good luck and wishing you quick healing.

 

[RubbaDubba1]

Owe boy, let's see how far I can push Anecdotal here. I had a Triple Arthrodesis 8.5 years ago on my left foot, non weight bearing for 12 weeks so I can relate. Arthritis is back, Achilles tendon & other issues. I just had a shoulder operation, read what I'm doing there. I can see some carry over, in both surgeries. [archived internal link]

Creatine Monohydrate 5mg daily, can help build muscle or help HOLD muscle I take Creatine HCL 1500mcg (= to 10mg monohydrate) as monohydrate doesn't agree with me. Creatine monohydrate supplementation, helps improve bone health by increasing bone mineral density and strength, especially in older adults. It aids by boosting bone-building cells (osteoblasts) and reducing bone breakdown, making it a safe, low-cost option for counteracting age-related bone loss. Daily supplementation of 3–5g supports protein synthesis, boosts muscle endurance, and helps retain muscle mass during intense training, cutting, or aging.

Tadalafil (Cialis) 5mg 2X daily, helps improve blood flow to the extremities, tendons, ligaments etc. The idea implied by my Longevity Dr and couple others online is, it can improve the effectiveness of peptides/medicine you're already taking. Can drop your Blood pressure a bit. watch

View: https://youtu.be/RgA4Hyr1Hbk?t=2690

45:00 - 47:30

Nitric Oxide Booster/beet juice helps in the same way the Tadalafil does.

Sports Research 5 types of Collagen supplement: Collagen is crucial for bone health, providing the structural scaffold for bone growth and repair, which supports bone fusion and remodeling. Collagen supplements may improve bone mineral density and aid fracture healing. It is frequently used in orthopedic surgery as a carrier for bone graft materials to encourage new bone growth.

Thymosin Alpha 1: is a naturally occurring peptide that accelerates healing by modulating the immune system, reducing inflammation, and stimulating growth factors. It supports tissue repair, aids in recovering from chronic infections, and boosts immune response, often used for musculoskeletal, autoimmune, and viral conditions.

Pentosan Polysulfate Sodium: (PPS) is an injectable agent, often used for osteoarthritis, shown to improve subchondral bone health, reduce bone marrow lesions/edema, and potentially support bone repair. It acts as an anti-inflammatory, anti-catabolic agent that stimulates tissue-protective mechanisms, reducing pain and improving bone density/metabolism.

 

[lessthanhalf]

I realise you do not really mean spending 6 months in bed, but avoiding that as much as is possible is a good idea for general health. That time scale is going to cause a lot of muscle wasting and loss of general fitness and conditioning, and depending on age it may be hard to recover that. Not to mention any of the other issues of long term bed rest like DVT etc. 100% worthwhile getting expert advice on managing this , I assume it is a physiotherapy/?OT issue, in conjunction with the surgeon. Managing this aspect of it well is likely to make a lot more difference than peptides or supplements. Essentially advice on what exercises to do to manage this issue as well as possible from an expert, and as much getting up and around within the limitations of the surgeon's advice on non weight bearing etc.

Most of the studies I have seen suggest good or better outcomes with GLP drugs after orthopaedic surgery, but I did see one recently that showed higher rates of non union in lower limb fractures with GLP's, so it might be worth trying to find that study or ask chatgpt about it, cannot remember the name of the study or I would link it here.