Good peptides to stack with Reta for Muscle growth

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IGF-1 LR3, this is only my 2nd time running it and I'm using it after a shoulder operation for repair. I've had both knees replaced and I used it for my 2nd knee replacement along with BPC-157/TB-500. The 2nd knee was night and day better on recovery, than the 1st one. This is my only frame of reference, so take it with a grain of salt. I have to get my other shoulder done, which is worse than the one I just had repaired and hoping this helps.

Insulin-like Growth Factor 1 Long Arg3—better known as IGF‑1 LR3 —is a modified version of the naturally occurring IGF‑1 hormone, prized for its ability to increase muscle hypertrophy, enhance recovery, and promote cellular growth. With a longer half-life and enhanced potency compared to standard IGF‑1, LR3 has quickly become a go-to peptide for athletes looking to build muscle, retain gains after a cycle, or accelerate healing. It can be used along side CJC-1295 no dac / Ipamorelin (which I'm taking) It can mess with your blood sugar a little, be careful on dosing and it needs to be mixed with Acetic Acid 0.6% to hold up in the fridge longer, compared to Bac water.
 
The cancer risks associated with hgh are a concern. I'd be keen to read up on some independent research. What I've read puts me off hgh . However I would like to understand if there is an ultra safe lower limit that has no cancer risk
 
Sid the SeaGull said:
The cancer risks associated with hgh are a concern. I'd be keen to read up on some independent research. What I've read puts me off hgh . However I would like to understand if there is an ultra safe lower limit that has no cancer risk
As I understand it there's no evidence it causes cancer, but if something's already there it could theoretically help it along, which is why baseline screening and IGF-1 monitoring matter more than avoidance. The research that puts most people off is referring to bodybuilding-range use. At low physiological doses (1-2 IU/day) you're largely just restoring levels you had fifteen years ago, not doing anything your body doesn't already do naturally during sleep and exercise.
 
Sid the SeaGull said:
I would like to understand if there is an ultra safe lower limit that has no cancer risk
Some cancer researchers even worry about dairy raising IGF-1. So to them, any unprescribed GH peptide use would be crazy. The safest/mildest GH peptide seems to be serm:

Gemini said:
Substance Mechanism Oncological Risk Profile Notable Characteristics Dairy Dietary/Indirect IGF-1 Low / Baseline Raises IGF-1 slightly; significant concern mainly for strict oncological diets. Sermorelin GHRH Analog Mild Risk Shortest half-life; lowest potential for chronic/uncontrolled growth signaling. Ipamorelin GHRP (Selective) Mild/Moderate Risk Highly selective for GH; lacks the "hormonal messiness" of older GHRPs. CJC-1295 (No DAC) GHRH Analog Moderate Risk Standard pulse enhancer; more stable than Sermorelin but still pulsatile. Tesamorelin GHRH Analog Moderate Risk Clinically approved for visceral fat; stronger IGF-1 push than Sermorelin. Tesamorelin + Ipamorelin GHRH + GHRP Stack Elevated Risk Synergistic "turbo" pulse; high peak IGF-1; potent for visceral fat loss. CJC-1295 (No DAC) + Ipa GHRH + GHRP Stack Elevated Risk The "Classic Stack"; mimics intense natural pulses; overrides natural troughs. GHRP-2 / GHRP-6 GHRP (Non-selective) Elevated Risk Non-selective; raises stress hormones (cortisol) and prolactin. Hexarelin GHRP (Potent) Elevated Risk Strongest GHRP; highest pulse intensity; potential for rapid desensitization. MK-677 (Ibutamoren) Oral Ghrelin Mimetic High Risk Continuous GH elevation; potential for 24-hour IGF-1 "over-exposure." CJC-1295 (with DAC) GHRH Analog High Risk Causes "GH bleed"; prevents the body from returning to low-growth baseline. Exogenous HGH Direct Hormone Highest Systemic Risk Bypasses feedback loops; direct systemic IGF-1 elevation. IGF-1 LR3 Long-Acting IGF-1 Extreme / Theoretical Danger Potent inhibitor of apoptosis; persistent signal for cell proliferation.
 
RENjutsu said:
Starting a new cycle of Reta soon - I am pretty consistent with weights but I was wondering what people's experienced were who stack peptides with reta for muscle growth, I've heard of CJC, ipamorelin but I have not researched much on them, does anyone take these with reta and what are your experiences? Worth taking for muscle growth?

I'm stacking reta, tesa, ipa and cyp, my muscle growth is insane, and I'm 56 y/o. Low doses on all, as I'm only 6-8 weeks in. I've actually gained 12 lbs, despite being in a caloric deficit (I'm sure there's a lot of water weight in there, and some muscle too). Belly is coming down a little at a time. I'm actually wondering if I can add KLOW, or if that would be too much. Thus far almost zero sides.
 
Just for context, a professional bodybuilder would/could put on about 10lbs of muscle in a year, with eating correctly, training heavy weights 3-6days a week, and being dosed up to the eyeballs on anabolics and exogenous growth hormone, not peptides. And these guys make it their business to be able to pack on as much muscle, as fast and efficiently as possible. The only time they're really touching peptides is for a cut on the run up to competition.

If people are trying to put on any reasonable amount of muscle, with peptides, they're in for a long slog.
 
I am currently in the process of ordering some Ipamorelin and Tesamorelin to go along with my Reta. So far I notice I'm more of a high dosage responder to reta. Which is not much of a concern but I do want to ensure that I maintain as much of my muscle as I possibly can. I also notice a slight decrease in my quality of sleep. Adding some tesa specifically can potentially help with sleep quality.
 
I'm fairly new here, but see this question a lot re peptides and muscle growth. People are in for a long slog if they're expecting muscle growth on peptides. They need to be looking at analobics/test/hgh if they want that side of things, but they come with a lot of risk.
 
mrmors said:
I'm fairly new here, but see this question a lot re peptides and muscle growth. People are in for a long slog if they're expecting muscle growth on peptides. They need to be looking at analobics/test/hgh if they want that side of things, but they come with a lot of risk.
Thought so too, seems the GH peps also not worth the risks
 
mrmors said:
I'm fairly new here, but see this question a lot re peptides and muscle growth. People are in for a long slog if they're expecting muscle growth on peptides. They need to be looking at analobics/test/hgh if they want that side of things, but they come with a lot of risk.
Some hcg if they want to keep everything downstairs working too.
 
RENjutsu said:
Thank you for the detailed response, I'm gathering, correct me if I'm wrong, that for muscle growth alone it is likely not worth it - you can see for reta for example it is well worth it for weight loss ( as I've experienced myself) but CJC ipamorelin from these responses doesn't seem to give that big benefit (unless I'm wrong)

Honestly secretagogues and hgh are not gonna give you dramatic results on muscle growth like test can. Test might be boring but its tried and tested for muscle growth. Just do short cycles and youll be fine.

RubbaDubba1 said:
Insulin-like Growth Factor 1 Long Arg3—better known as IGF‑1 LR3 —is a modified version of the naturally occurring IGF‑1 hormone, prized for its ability to increase muscle hypertrophy, enhance recovery, and promote cellular growth. With a longer half-life and enhanced potency compared to standard IGF‑1, LR3 has quickly become a go-to peptide for athletes looking to build muscle, retain gains after a cycle, or accelerate healing. It can be used along side CJC-1295 no dac / Ipamorelin (which I'm taking) It can mess with your blood sugar a little, be careful on dosing and it needs to be mixed with Acetic Acid 0.6% to hold up in the fridge longer, compared to Bac water.

IGF-1 is also not as potent for muscle growth as you may think. It does not directly affect hypertrophy but simply promotes cellular growth. This should cause alarms bells because IGF-1 is known to be associated with a variety of cancers and high IGF-1 gives poor prognosis. IGF-1 is to me strictly in the too risky category. Id even rather try HGH than that.
 
TLDR: there are no peptides that directly affect muscle growth. There are peptides that will help you recover better, sleep better, push harder, etc.
 
Devilseye said:
Honestly secretagogues and hgh are not gonna give you dramatic results on muscle growth like test can. Test might be boring but its tried and tested for muscle growth. Just do short cycles and youll be fine.

IGF-1 is also not as potent for muscle growth as you may think. It does not directly affect hypertrophy but simply promotes cellular growth. This should cause alarms bells because IGF-1 is known to be associated with a variety of cancers and high IGF-1 gives poor prognosis. IGF-1 is to me strictly in the too risky category. Id even rather try HGH than that.
Ive always heard that test messes up your natural production and even short cycles are worthless, will you not lose the majority of the muscle mass when you come off a cycle?
 
Sid the SeaGull said:
The cancer risks associated with hgh are a concern. I'd be keen to read up on some independent research. What I've read puts me off hgh . However I would like to understand if there is an ultra safe lower limit that has no cancer risk
Same for myself - I found the same from IGF LR3 too
 
RENjutsu said:
Ive always heard that test messes up your natural production and even short cycles are worthless, will you not lose the majority of the muscle mass when you come off a cycle?
It will for sure mess with your production. You can go on HCG while using test and after discontinuing but there's no guarantee your production will be at the same level.
 
RENjutsu said:
Ive always heard that test messes up your natural production and even short cycles are worthless, will you not lose the majority of the muscle mass when you come off a cycle?
Ok so yes it does mess up your natural production. However you can either run doses of HCG at the same time or follow a very strict PCT.

Whilst you do lose some muscle mass you can curtail this If you dial in your PCT and nutrition. You will still lose some mass ( mostly water weight) but not as much as if you did nothing at all .
 
Great discussion, currently on reta & cjc + ipa, hopefully will start to see some body recomp in the coming few months
 
Low dose of 1-2IU of HGH x 5/week it helps out. From my research, troubles starts at a higher doses and ignoring blood work
 
morti said:
Great discussion, currently on reta & cjc + ipa, hopefully will start to see some body recomp in the coming few months
Looking forward to hearing how the CJC/IPA work for you. I am thinking about starting these in about five weeks when work slows down and I can deal with the possibility of sleep interruption.
 
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