I don't know how old your wife is, but a lot of women these days experience perimenopausal symptoms from their mid-late thirties and the first thing they experience is sleep disturbance. If she is around 40 and isn't on HRT, this could be something to look into as well.DragonOfTheSea said:
Epithalon
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DragonOfTheSea
GLP-1 Enthusiast
Oh for sure. She is 43 and yes has been experiencing perimenopausal symptoms for about 2 years now. While her sleep has been worsening during this time, what it’s been like since starting GLPs was definitely a sudden, dramatic and consistent shift which is why I’m these options for her.miameow said:
We’re definitely looking into HRT as well, her 2 sisters-in-law are both a couple years older and both on it- chirping in her ear about it. I appreciate the suggestion
trojanpeptide
GLP-1 Enthusiast
I was just reading that one of the best longevity products for women is ... HRT.I saw that recently. (linked)miameow said:
DragonOfTheSea
GLP-1 Enthusiast
Interesting read, thank you. Seeing a lot more about Tadalafil as well lately..
Peptoidian
GLP-1 Apprentice
I cycle it EOD with DSIP. The combo works best for me. Reliably doubles my deep sleep as measured by my Apple watch.
I’m glad to hear it’s on her radar. Progesterone drops first, before estrogen, and many women experience significantly better sleep from oral micronized progesterone alone. Weight loss will throw off an already declining e/p/t - and it’s a well-known fact that even young female bodybuilders go on hrt during aggressive cuts. Hope you find something that works for her.DragonOfTheSea said:Oh for sure. She is 43 and yes has been experiencing perimenopausal symptoms for about 2 years now. While her sleep has been worsening during this time, what it’s been like since starting GLPs was definitely a sudden, dramatic and consistent shift which is why I’m these options for her.
We’re definitely looking into HRT as well, her 2 sisters-in-law are both a couple years older and both on it- chirping in her ear about it. I appreciate the suggestion
DragonOfTheSea
GLP-1 Enthusiast
Yeah one of her SIL gave her some PR pills and an Estradiol Patch to test run.. she hasn’t used either yet.miameow said:
… what were we talking about? Oh right Epithalon
kinda went OT here, sorry folks!Well, whatever gets her to sleep. Epi could be beneficial, but at the end of the day, hormones need to be the foundation. I’ll check back in when I get my epi shipment as I’ve not been on it, yet!DragonOfTheSea said:Yeah one of her SIL gave her some PR pills and an Estradiol Patch to test run.. she hasn’t used either yet.
… what were we talking about? Oh right Epithalon
laansasa
GLP-1 Enthusiast
I am 46 struggling with the same. Before considering HRT, I plan too try kisspeptin (which I just received). It is supposed to signal your hypothalamus to produce sex hormones.DragonOfTheSea said:Yeah one of her SIL gave her some PR pills and an Estradiol Patch to test run.. she hasn’t used either yet.
… what were we talking about? Oh right Epithalon
laansasa
GLP-1 Enthusiast
Good to know, thank you! I wonder if cycling it through the month would be ok.CandyCap said:
cheaperseeker
GLP-1 Enthusiast
Note to self: Wait until you're in full-on menopause to try kisspeptinCandyCap said:
It has been used in fertility clinics to bring on ovulation in those struggling with things like PCOS. I would definitely research a bit more on dosages, etc. Many studies use Kisspeptin-54, instead of the weaker Kisspeptin-10 that we have access too. You could also try making a nasal spray with it (it crosses the blood/brain barrier), which would lesson dosage a bit.laansasa said:
laansasa
GLP-1 Enthusiast
A nasal spray is a great idea since I dread pinning and adding more to the pile is one of the reasons I haven't started yet... thank you!CandyCap said:
Celestar62
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Mind sharing where?vale113 said:
CNCCurrency
GLP-1 Specialist
laansasa said:
https://pep-pedia.org/peptides/kisspeptin
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