Thanks for that link , I was not aware any results existed yet for this, and the results are amazing.
Elora 3 mg + TZP 5 mg: Weight loss -17.0%
confirms my guess that low dose elora plus low dose reta or tirz might work really well with low side effect rates ( presumed )
Elora 9 mg (3 mg start) + TZP 15 mg: Achieved retatrutide like -29.0% reduction in body weight (a treatment difference of -11.2%)
This is the best result ever seen for any GLP as far as I know, only 3 patients so preliminary but only over 32 weeks so almost zero chance this is at plateau, and it shows an added 11.2% weight loss over tirz alone, which while not truly additive might be enough to get a lot of more severely obese people to normal or near normal weights. There is a very good chance there could be an extra 10-15% more weight loss if followed for another 30-40 weeks, as it was already as effective as 72 weeks of 12mg reta. Plus if it was reta instead of tirz there could be an extra 5%, so in theory you might get to 40-45% weight losses over more than a year, and maybe as high as 50% with reta and elora. This could be enough for all but the extremely severe obese with BMI's of 50+, and definitely could rival surgery.
Elora 9 mg (3 mg) + TZP 15 mg (Combo)- Resulted in another retatrutide like weight loss of 25.5% 12/16 completed, 4 dropouts, maybe due to excessively fast weight loss is speculated
Really just confirms the previous result, but with more completed numbers and 25% in 6 months is amazing
These results were in those without severe obesity- Average BMI was low at 32.8 and 30.5, so are likely to be better in those more overweight, and it seems they might need to slow down the dosing increases as it is speculated in the article that weight loss rates could have been excessive causing withdrawls from the study.