Eli Lilly’s new medication for alcoholism?

[LabTesting]

I saw a TikTok the other day about a new GLP drug for alcoholism that was entering Phase 3 trials.

Now I can’t find the name of it, and I wanted to know what makes it different from the others (what specifically makes it for alcoholism).

I’ve searched and can’t find it, maybe its not real?

I want to look into it more for people I know who are fighting alcoholism.

if real until its out on a grey market even does anyone know what glps seems to be the best for alcoholism?

 

[nevets]

I believe there's been evidence that GLP1 drugs affect dopaminergic pathways (think of how you feel while you are eating food and food noise) and the effect carrying over to alcohol use disorder. I'm not sure about the specific mechanism that targets alcohol use disorder but I also do remember seeing something about it. I'd assume the current GLP1's like tirzepatide could be helpful with alcohol use disorder

 

[high-tide]

Not sure about alcoholism but when I started reta, my desire to drink alcohol really vanished. It was odd but I'm looking at some delicious IPA's in my fridge and not enticed in the least

 

[LabTesting]

Not sure about alcoholism but when I started reta, my desire to drink alcohol really vanished. It was odd but I'm looking at some delicious IPA's in my fridge and not enticed in the least

yes there is a lot of chatter and stories of the same!

In fact my first post here was about it . I have friends who have said what you are saying and this Thread goes into it:

[archived internal link]

But i seen a specific one for it but maybe is was BS

 

[chmuse]

Sema curbed my alcohol cravings significantly when I first started. I managed to spend a good amount of time sober, which was about a 90% improvement over my previous consumption. That being said, life events did eventually overpower the aversion. I'm still drinking less, but I'm also drinking almost daily again- I'd say 50% of what I had before starting a glp.

I was technically started on sema for metabolic syndrome (I was on a medication for years that is known for causing it) but the reason I requested it was I knew I was approaching a life ruining amount of liquor. If you can figure out which one it is, I'd love to hear about it. I'm so excited for SUD to be a legitimate reason to be prescribed. It will be life changing for people.

 

[tncc_rn]

I believe there's been evidence that GLP1 drugs affect dopaminergic pathways (think of how you feel while you are eating food and food noise) and the effect carrying over to alcohol use disorder. I'm not sure about the specific mechanism that targets alcohol use disorder but I also do remember seeing something about it. I'd assume the current GLP1's like tirzepatide could be helpful with alcohol use disorder

This....

And Eli Lilly is looking for new indications for Trizepatide to gain patent extensions.

Went through this with Allergan doing Botox P.E. studies working for my Ex.

She gave them 28 years worth of patent extensions with the studies she submitted to FDA.

It's a real thing....

 

[mlke6]

it was like the third result on google. Maybe Brenipatide?

 

[lessthanhalf]

Yes Lily is researching Brenipatide for alcohol use disorder. There is a phase 3 trial happening , but no results yet. I was a bit surprised they are researching a separate drug for this, as all of the GLP-1 drugs have this effect, but I can only guess they don't want to confuse or put off their customers for tirzepatide. While it is not yet proven enough to be generally recommended as a treatment for alcoholism, there is a ton of preclinical evidence that it works and lots of statistical reanalyses of studies of glp-1 drugs that show reductions in drug and alcohol use, reductions in hospital admissions and reductions in overdoses. Once studies like the one Lily is doing and no doubt many others, it will possibly end up as the most effective treatment there has ever been for alcoholism and possibly also opiate and other drug abuse as well.

In terms of which one is better, I do not think there is any solid science yet, but the effect has been shown for tirzepatide and semaglutide in studies and from a huge number of anecdotal reports on this forum, that the medication has reduced their drinking.

 

[peptidepower77]

Not sure about alcoholism but when I started reta, my desire to drink alcohol really vanished. It was odd but I'm looking at some delicious IPA's in my fridge and not enticed in the least

Yah, I used to get bored from time to time and go down to the local pub for a few pints. Even though I still get bored, whenever I think of going down for a beer I just lose interest now. I don't really have any desire to drink these days.

 

[miss-sanne]

Are you thinking about Brenipatide ?

It's also in trial for astma, I think.

 

[LabTesting]

it was like the third result on google. Maybe Brenipatide?

I searched alot and did 2 ai searches Grok and Chat. NOTHING came up

thank you

 

[LabTesting]

Are you thinking about Brenipatide ?

It's also in trial for astma, I think.

Yes! as i said in the comment above I searched with no luck. I don't know how i missed it

You guys are great! thank you

 

[latviantower]

Tirz killed my desire to drink. Coming up on 3 year sobriety milestone. GLP’s better than Naltrexone.

 

[desinr-gal]

I believe there's been evidence that GLP1 drugs affect dopaminergic pathways (think of how you feel while you are eating food and food noise) and the effect carrying over to alcohol use disorder. I'm not sure about the specific mechanism that targets alcohol use disorder but I also do remember seeing something about it. I'd assume the current GLP1's like tirzepatide could be helpful with alcohol use disorder

absolutely. I haven't even wanted a drink since I started. Im 6.5 months zero alcohol.

 

[brettbierjunkie]

On reta, but I don't desire drinking unless I'm craving a certain flavor(depends on general feel/vibes) or I am on vacation and it's social drinking hours. Even then, I still drink a lot less as I get buzzed quicker. Was difficult before as my husband is a big craft beer drinker and my personal stash is sitting in the garage fridge. If I feel shitty or spent, I sleep or do something else now. Used to not be that way at all.

 

[desinr-gal]

Sema curbed my alcohol cravings significantly when I first started. I managed to spend a good amount of time sober, which was about a 90% improvement over my previous consumption. That being said, life events did eventually overpower the aversion. I'm still drinking less, but I'm also drinking almost daily again- I'd say 50% of what I had before starting a glp.

I was technically started on sema for metabolic syndrome (I was on a medication for years that is known for causing it) but the reason I requested it was I knew I was approaching a life ruining amount of liquor. If you can figure out which one it is, I'd love to hear about it. I'm so excited for SUD to be a legitimate reason to be prescribed. It will be life changing for people.

I love your new avatar

 

[desinr-gal]

absolutely. I haven't even wanted a drink since I started. Im 6.5 months zero alcohol.

9 months..0 alcohol

 

[Sasquatch]

Yep. I saw some bald guy hawking something on TV. Three letters? Looked like some compounding health and wellness dude. Yawn.

I also used to love my martinis. Tirz. took that away. Also 70lbs. so can i bitch?

 

[DazDillinger]

I used to and enjoyed getting hammered every Saturday. Wife and I would have some wine but I wanted to get lit so I would always sneak some hard booze and drink extra. Started Reta in June. I have no interest in alcohol and haven’t been drunk since July. We will open a bottle of wine and sometimes I don’t even finish the first glass I just dump it out and I’m perfectly content doing so

 

[Minkster]

I believe there's been evidence that GLP1 drugs affect dopaminergic pathways (think of how you feel while you are eating food and food noise) and the effect carrying over to alcohol use disorder. I'm not sure about the specific mechanism that targets alcohol use disorder but I also do remember seeing something about it. I'd assume the current GLP1's like tirzepatide could be helpful with alcohol use disorder

Since starting Reta I have absolutely zero interest in alcohol. Tried to drink some Xmas day and really couldn't the feel the alcohol at all but then later just generally felt like crap.