Dosing schedule

[Crowreap]

The glucagon effect is interesting and amazing. What are you working on at the gym? Did you notice anything with your heart rate that caused any concern?

At the gym, it's nothing complicated. I just do the push-pull legs split. And I feel like I can definitely feel the glucagon effect because earlier in the year, when I was doing 1500 calories daily, and this was without taking reta, I noticed that my sleep quality was pretty good, but now I'm back on 1500 with reta and I noticed that my sleep quality is kind of weird. I'm really tired, more tired than I used to be. And it could be that my metabolism has increased because the beats per minute is increased, I think by reta, so I just am overall more tired before bed, and I sleep more now than I used to. But I did not notice anything that caused any concern regarding the heart rate. I just am noticing on reta my metabolism is a lot faster, but since I am on it, I don't feel any appetite. So I guess that's really good.

 

[Crowreap]

I do metabolic conditioning 4 days a week and wear HR monitor. I haven’t noticed any changes in my HR working out. My resting HR was 60 and over the last 5 days it’s gone down to 52. Kinda weird.

I think that makes sense that it has gone down because you are losing fat and leaning out, so that's what I've noticed, that my resting heart rate has gone down quite a bit. And I find doing cardio so much easier now because I've lost quite a lot of weight. So for example, the treadmill or the stairmaster, it's like easy mode now, and I could go on for much longer.

 

[kobeanbry24]

At the gym, it's nothing complicated. I just do the push-pull legs split. And I feel like I can definitely feel the glucagon effect because earlier in the year, when I was doing 1500 calories daily, and this was without taking reta, I noticed that my sleep quality was pretty good, but now I'm back on 1500 with reta and I noticed that my sleep quality is kind of weird. I'm really tired, more tired than I used to be. And it could be that my metabolism has increased because the beats per minute is increased, I think by reta, so I just am overall more tired before bed, and I sleep more now than I used to. But I did not notice anything that caused any concern regarding the heart rate. I just am noticing on reta my metabolism is a lot faster, but since I am on it, I don't feel any appetite. So I guess that's really good.

More sleep = more muscle recovery. I agree, sound like good effects to me. 2nd day on reta and I'm sleeping earlier which personally I like, if I'm out before 930pm I'm a happy camper. Woke up a bit lethargic today but I'm also taking 10mg melatonin and 500 mg Mag Gly. Might cut the melatonin dosage in half and see if it changes anything. It's good to know you didn't notice anything concerning with your heart rate. Cheers

 

[birdwhacker]

Reading about these doses are always crazy to me. I started on 0.5mg... Then did another 0.5 every two days until I hit 2mg for the week.

Then I stayed at 1mg per three days for a month, and now I'm on 2mg every three days. I suppose it wouldn't be neccessary to take as much if I didn't need to counter hunger/"food noise" so much, but still.

When I hear about people getting strong side effects at 0.5, I have to wonder if they're getting proper supplemental nutrition. My first dose of 0.5mg I noticed some muscle twitching, skin sensitivity, heightened sense of smell, a handful of other things, but the only thing that persisted was the heightened sense of smell, and of course the intended effects like suppressed hunger/thirst and sickness after overeating.

 

[kobeanbry24]

I think that makes sense that it has gone down because you are losing fat and leaning out, so that's what I've noticed, that my resting heart rate has gone down quite a bit. And I find doing cardio so much easier now because I've lost quite a lot of weight. So for example, the treadmill or the stairmaster, it's like easy mode now, and I could go on for much longer.

I'm looking forward to cardio becoming easier. I have massive calves so being about 40 lbs overweight makes even just 3 mins of jumping rope sets my calves on fire. Also, also I enjoy a nice run, with the extra weight, running can become a pain in the knees. Also, getting rid of the abdominal fat should help with my back pain.

 

[kobeanbry24]

Reading about these doses are always crazy to me. I started on 0.5mg... Then did another 0.5 every two days until I hit 2mg for the week.

Then I stayed at 1mg per three days for a month, and now I'm on 2mg every three days. I suppose it wouldn't be neccessary to take as much if I didn't need to counter hunger/"food noise" so much, but still.

When I hear about people getting strong side effects at 0.5, I have to wonder if they're getting proper supplemental nutrition. My first dose of 0.5mg I noticed some muscle twitching, skin sensitivity, heightened sense of smell, a handful of other things, but the only thing that persisted was the heightened sense of smell, and of course the intended effects like suppressed hunger/thirst and sickness after overeating.

People react differently to different things. My wife, all her side effects so far were positive, increased energy and seemingly better mood. For me, the side effect was a slight headache and fatigue, the fatigue surprised me because I just had TRT pellets put in 10 days ago. It seems I'm more sensitive to reta than my wife. But on a positive note we both have already experienced the intended effect of appetite suppression and less food noise.

My wife has decided to step up to 1mg in week 2. I'm still on the fence and leaning towards another week at .5 before stepping up to 1mg. For me, supplementation isn't an issue, I'm eating clean, taking my vitamin stack and drinking my water and electrolytes.

 

[Crowreap]

More sleep = more muscle recovery. I agree, sound like good effects to me. 2nd day on reta and I'm sleeping earlier which personally I like, if I'm out before 930pm I'm a happy camper. Woke up a bit lethargic today but I'm also taking 10mg melatonin and 500 mg Mag Gly. Might cut the melatonin dosage in half and see if it changes anything. It's good to know you didn't notice anything concerning with your heart rate. Cheers

thanks! 9:30 p.m. is like staying up late for me. LOL. I go to sleep at around 8 o'clock. Does the melatonin make a difference? I also heard there's another peptide called DSIP that is supposed to induce some sort of sleep state. I'm thinking that might be something good to add on. I still gotta do a lot more research on it, though.

 

[Crowreap]

I'm looking forward to cardio becoming easier. I have massive calves so being about 40 lbs overweight makes even just 3 mins of jumping rope sets my calves on fire. Also, also I enjoy a nice run, with the extra weight, running can become a pain in the knees. Also, getting rid of the abdominal fat should help with my back pain.

Yeah, it's so insane, the cardio becomes effortless. Like I can stay on those machines forever. That's what it feels like at least. Previously, without reta, while on those cardio machines, I would get so hungry. It was insane. Now I have maximum energy, and it's so weird because I'm sweating like crazy, yet I don't feel any of the effects like fatigue and hunger and those kinds of things that typically want you to stop the cardio. Also, if running is a pain, what you could do is, what I do is incline treadmill at a decent pace, so that it doesn't wreck your ankles and knees.

 

[kobeanbry24]

thanks! 9:30 p.m. is like staying up late for me. LOL. I go to sleep at around 8 o'clock. Does the melatonin make a difference? I also heard there's another peptide called DSIP that is supposed to induce some sort of sleep state. I'm thinking that might be something good to add on. I still gotta do a lot more research on it, though.

The melatonin has quite the effect on me. I take it in gummy form. About 10 minutes after I take it, I'm asleep, unless I'm on my phone or have the TV on, of course. It's also a powerful anti-oxidant to boot. I also put on some rain sounds to cue for my brain that it's time to sleep. Quality of sleep has become so precious to me so I have black out curtains, I've learned the less light in the room the better your quality of sleep.

 

[Crowreap]

Reading about these doses are always crazy to me. I started on 0.5mg... Then did another 0.5 every two days until I hit 2mg for the week.

Then I stayed at 1mg per three days for a month, and now I'm on 2mg every three days. I suppose it wouldn't be neccessary to take as much if I didn't need to counter hunger/"food noise" so much, but still.

When I hear about people getting strong side effects at 0.5, I have to wonder if they're getting proper supplemental nutrition. My first dose of 0.5mg I noticed some muscle twitching, skin sensitivity, heightened sense of smell, a handful of other things, but the only thing that persisted was the heightened sense of smell, and of course the intended effects like suppressed hunger/thirst and sickness after overeating.

I just pin one 1 mg per week. I've seen a lot of people, such as yourself, do every x amount of mg per days, like every two days or every three days. Does that make any difference? For me, that 1mg, it does pretty well for me. I don't experience anything that I would need to re-pin again in the same week, but I think everyone's different.

 

[birdwhacker]

I just pin one 1 mg per week. I've seen a lot of people, such as yourself, do every x amount of mg per days, like every two days or every three days. Does that make any difference? For me, that 1mg, it does pretty well for me. I don't experience anything that I would need to re-pin again in the same week, but I think everyone's different.

So I use it purely for appetite control. There's a myth that dosing once weekly keeps receptors sensitive, and that's not true at all. You can dose every 3, 5, or 7 days as you feel comfortable. The half life is six days. I think if I wasn't worried about appetite control, I would probably be dosing every five or six days just to keep blood levels steadier.

But yeah, the big benefit to dosing every 3 days is appetite suppression. I become incredibly hungry 4 or 5 days after dosing. Since going up to 4.6mg per week, I've actually found the hunger even harder to deal with. I think it's mostly a discipline and lifestyle issue on my part, and a desire to sustain 3lbs/wk losses minimum, but it really does make me consider adding cagri or tirz to the mix.

 

[Crowreap]

The melatonin has quite the effect on me. I take it in gummy form. About 10 minutes after I take it, I'm asleep, unless I'm on my phone or have the TV on, of course. It's also a powerful anti-oxidant to boot. I also put on some rain sounds to cue for my brain that it's time to sleep. Quality of sleep has become so precious to me so I have black out curtains, I've learned the less light in the room the better your quality of sleep.

Yeah, I do exactly that. Pitch black room and there's a noise machine. I also make sure the room is pretty cold as well. So I fall asleep pretty fast since I'm tired from my early morning workout and then the fatigue catches up to me near my bedtime. My only issue is that I keep getting up to use the bathroom lol i gotta stop drinking too much water! But I cant because reta makes me so dehydrated so im just spamming water all day. . Are yall experiencing the dehydration as well?

 

[Crowreap]

So I use it purely for appetite control. There's a myth that dosing once weekly keeps receptors sensitive, and that's not true at all. You can dose every 3, 5, or 7 days as you feel comfortable. The half life is six days. I think if I wasn't worried about appetite control, I would probably be dosing every five or six days just to keep blood levels steadier.

But yeah, the big benefit to dosing every 3 days is appetite suppression. I become incredibly hungry 4 or 5 days after dosing. Since going up to 4.6mg per week, I've actually found the hunger even harder to deal with. I think it's mostly a discipline and lifestyle issue on my part, and a desire to sustain 3lbs/wk losses minimum, but it really does make me consider adding cagri or tirz to the mix.

Oh wow, that's a pretty aggressive weight loss schedule. Right now, I'm at about 1.5 to 2 pounds a week. Sometimes it goes to 1 pound a week, but it's slowing down now because I'm getting a bit too lean. It is pretty crazy, though, how you're experiencing appetite go up quite a bit because I haven't felt hunger since like two weeks ago, and I started three weeks ago. And I'm on such a low dose, just 1mg. whats your starting weight and goal weight and current weight?

 

[kobeanbry24]

Yeah, I do exactly that. Pitch black room and there's a noise machine. I also make sure the room is pretty cold as well. So I fall asleep pretty fast since I'm tired from my early morning workout and then the fatigue catches up to me near my bedtime. My only issue is that I keep getting up to use the bathroom lol i gotta stop drinking too much water! But I cant because reta makes me so dehydrated so im just spamming water all day. . Are yall experiencing the dehydration as well?

Yes, my lips have been dry and my legs ashy lol and I've been pounding electrolyte drink like crazy and using the bathroom alot. But I think my body is getting used to the reta because I'm doing better this afternoon, experiencing no side effects now.

 

[birdwhacker]

Oh wow, that's a pretty aggressive weight loss schedule. Right now, I'm at about 1.5 to 2 pounds a week.

Consistency is key. I haven't really lost anything this last week because my appetite has been getting the better of me, and I don't have access to a gym so I rely on cardio alone to push it along. I also have an extremely unfulfilling personal life and am unemployed; the earlier progress and the current plateau can both be attributed to this in a way, lol.

Sometimes it goes to 1 pound a week, but it's slowing down now because I'm getting a bit too lean.

That's a problem I wouldn't mind having.

It is pretty crazy, though, how you're experiencing appetite go up quite a bit because I haven't felt hunger since like two weeks ago, and I started three weeks ago. And I'm on such a low dose, just 1mg. whats your starting weight and goal weight and current weight?

I think appetite suppression was the best for me around the 3 week mark, at 2.3mg per week.

Starting weight was 236, current weight is around 217. 6 foot white male. Goal weight is 185, but when I get closer to 200 or the appetite suppression wears off I'm going to have to rethink my approach and gain access to a gym. I'm not a particularly motivated individual and I have poor self control, so this is all pretty difficult.

Thanks for asking me about my favorite topic

 

[birdwhacker]

Yes, my lips have been dry and my legs ashy lol and I've been pounding electrolyte drink like crazy and using the bathroom alot. But I think my body is getting used to the reta because I'm doing better this afternoon, experiencing no side effects now.

Dry lips and pounding electrolyte drinks sounds like dehydration to me.

Let me red pill you on electrolytes, pretty please:

Any electrolyte drink with less than 800mg of potassium in the bottle is a scam. Coconut water is one of the best sources for potassium, and most people don't have trouble getting enough sodium.

You can take out the guesswork on potassium with a product like "Dr. Berg Electrolyte Powder" from Amazon. It has 1000mg of potassium, which is enough to be effective but not enough to be dangerous (some products have 2g of potassium). The RDA for potassium is in the neighborhood of 4g per day. I would personally add salt to a product like this. In-fact I do so every morning.

Don't sleep on salt. A bit fucking pinch of table salt in a glass of water first thing in the morning will solve 90% of your electrolyte problems and likely be more effective than expensive fruity hydration drinks. Enough that the water tastes somewhat salty and not just a little weird, but not salty like seawater. Enough that you can say, "yes, this is indeed salt water." That's your morning dose. Any product with less than 200mg of sodium isn't effectively hydrating along that route.

I usually just shake an assload of salt into a glass along with potassium salt in the morning, eyeballed in a 1:3 ratio. If I drink this, I rarely need more electrolytes later in the day unless I'm sweating a ton.

This ball knowledge has been life changing for me and I hope you take it to heart.

 

[kobeanbry24]

Dry lips and pounding electrolyte drinks sounds like dehydration to me.

Let me red pill you on electrolytes, pretty please:

Any electrolyte drink with less than 800mg of potassium in the bottle is a scam. Coconut water is one of the best sources for potassium, and most people don't have trouble getting enough sodium.

You can take out the guesswork on potassium with a product like "Dr. Berg Electrolyte Powder" from Amazon. It has 1000mg of potassium, which is enough to be effective but not enough to be dangerous (some products have 2g of potassium). The RDA for potassium is in the neighborhood of 4g per day. I would personally add salt to a product like this. In-fact I do so every morning.

Don't sleep on salt. A bit fucking pinch of table salt in a glass of water first thing in the morning will solve 90% of your electrolyte problems and likely be more effective than expensive fruity hydration drinks. Enough that the water tastes somewhat salty and not just a little weird, but not salty like seawater. Enough that you can say, "yes, this is indeed salt water." That's your morning dose. Any product with less than 200mg of sodium isn't effectively hydrating along that route.

I usually just shake an assload of salt into a glass along with potassium salt in the morning, eyeballed in a 1:3 ratio. If I drink this, I rarely need more electrolytes later in the day unless I'm sweating a ton.

This ball knowledge has been life changing for me and I hope you take it to heart.

Love it, thanks for the great information

 

[birdwhacker]

Love it, thanks for the great information

That's what I'm here for Pimp.

 

[kobeanbry24]

That's what I'm here for Pimp.

Playa to playa, pimp to pimp

 

[dondada109]

I'm not overweight I'm actually fairly lean with a good amount of muscle. I'm 1.82m tall, weigh around 78kg, and sit at roughly 14% body fat. The problem is that it takes a lot to fight the food noise. I'm usually someone who can easily eat 5,000 calories a day without even feeling bad, so I started Retatrutide, to go for a little cut.

I started on April 23rd with 0.5mg. Three days later (April 26th), I took another 0.5mg because I felt like there was a slight peak in appetite suppression, but it faded pretty quickly.

Then on April 29th, I took 1mg straight, and last Sunday I did 1.5mg. After five days from Sunday, I'm planning to increase the dose to 2mg. Honestly, I feel pretty good on my cut right now. I still have food noise, but it's much easier to control.

The biggest difference I've noticed is digestion. When I eat a meal, it feels like it takes forever to digest, so I stay full way longer than my body is used to and my body reacts way better to carbs as pre workout, sometimes even better with an intra drink like maltodextrin, way more consistent power throughout the workout.

I'll keep track of my journey and would love to follow yours as well. I think my dose will probably end up around 3mg within the next 3–4 weeks. I'll keep you updated!