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The only reason I would be less conservative would be if you wanted more effects on labwork, like if you had high cholesterol or triglycerides, prediabetes, or elevated liver enzymes. Or if you have high blood pressure. But the weight loss alone would be helping as well.
 
Calm Logic said:
The only reason I would be less conservative would be if you wanted more effects on labwork, like if you had high cholesterol or triglycerides, prediabetes, or elevated liver enzymes. Or if you have high blood pressure. But the weight loss alone would be helping as well.
It's been a while since I have seen a doctor, but it is high on my list of priorities once I have time I can take away from work. Strictly off feel, I'm fairly certain I am in pretty decent health. I want to get a full checkup and blood panel done. What's the likelihood the doc or the vampire will be able to tell someone is using peptides from the bloodwork? That's something I haven't thought about before today. From your(collective) experiences, do you tell them you are injecting and what you are injecting? Do they ever care?
 
keangkong said:
folks who haven’t tried other GLP-1 drugs should start with an already approved GLP-1 drug because Reta hasn’t made it out of clinical trials. Yes, I know initial results seem promising, but that doesn’t make up for the lack of data and review so far. However, I don’t want to be too preachy: I do take Reta.
I'm not mad about starting with sema. I lost at least 17 pounds in the first month and a half. I'm going to try and stick with it for a bit by itself. If I stall maybe I'll add in a bit of reta to the mix. But that is for future me to deal with.
 
kaahhllll said:
It's been a while since I have seen a doctor, but it is high on my list of priorities once I have time I can take away from work. Strictly off feel, I'm fairly certain I am in pretty decent health. I want to get a full checkup and blood panel done. What's the likelihood the doc or the vampire will be able to tell someone is using peptides from the bloodwork? That's something I haven't thought about before today. From your(collective) experiences, do you tell them you are injecting and what you are injecting? Do they ever care?
No one gives a shit about us patients 🙂 And with no previous bloodwork to go by, they will have no clue.

I am on compounded tirz, but I will tell them the same when I am on reta. It's good to tell them you are on a GLP, and they will want to know the dose too. So in your case, I would tell them you are on 2.5 mg of compounded tirz (instead of 0.5 mg of reta).

In a perfect world, docs can help prevent uncommon GLP symptoms like pancreatitis. For example, high triglycerides above 500 are a risk factor for pancreatitis.
 
kaahhllll said:
https://a.co/d/8Mt2KFM

This is the exact scale I have been using for a couple years now.
It's amazing. I love using it and playing with the app (of the same name, Arboleaf). Thanks again.
 
PackmanJohnny said:
I dont plan on being on these forever. I ran a few sample packs of Ozempic I got from a doctor who gave me extra because I pretended like I was gonna pay him 1100$/month for it, I dont remember the exact dosage, 4 or 5 pens worth. It was cool to not be hungry, but I already take Adderall for ADD and dont have a snack/hunger problem, and my A1C is actually within range on my bloods. Also not a fan of some of the long term sides Ive seen from Sema (tirz seems ok).

Reta is attractive because of the GCGR agonist and Im SUPER interested in the liver fatty acid release/reduction in FLD risk I read in a study. if I was ONLY interested in straight up weight loss by any means necessary Id stick to Tesa/GH. I have a lot of muscle I want to retain and am in a place in life where Im just not training much and have accepted that - Thats really the only reason a GLP-1 looks super attractive to me.

GH is the real deal - Wish I could afford to be on it permanently and plan to one day. My experience was life changing. Only second to Test as far as quality of life increase lol
How is your heart rate? Adderall and reta are both known to increase heart rate. I wanted to try it, but feared the side effects of mixing both.
 
Calm Logic said:
It's amazing. I love using it and playing with the app (of the same name, Arboleaf). Thanks again.
Yeah I have been really happy with that scale and app. I appreciate the goal tracking at the bottom of the main page. There is a slight discrepancy between its composition readings and that of my galaxy watch. But its a good baseline to go off of. I'm glad I could help!
 
Mustafa said:
How is your heart rate? Adderall and reta are both known to increase heart rate. I wanted to try it, but feared the side effects of mixing both.
All GLP1s increase heart rate. Reta's increase is MAYBE 1-2bpm more than the others.
 
To quote the reta joke by @Morbius: KABOOM!

Even my experimental use of the heart stimulant clenbuterol (40 mg cycle) raised my resting heart rate by only 2 bpm. Like from 67 bpm (on tirz) to 69 bpm (on tirz plus clen).

OTOH, there are at least a few people in this forum who have discontinued reta over elevated heart rate. For milder cases where you have a whole kit of reta left, a beta blocker may help (even from telehealth or India).
 
zpped said:
All GLP1s increase heart rate. Reta's increase is MAYBE 1-2bpm more than the others.
此外,静息心率确实需要像健身手表这样的持续监测设备来追踪,任何低于100次/分的静息心率目前都没有已知的不良后果或因果关系。

每种GLP-1受体激动剂都会对静息心率产生影响,但由于每项研究的具体情况不同,因此很难进行比较。不过可以肯定的是,大多数服用GLP-1受体激动剂的人都会出现0-10次/分的暂时性静息心率升高。这种升高通常会随着时间推移而减弱。

此外,还有一种与血压相关的瞬时心率效应。当血压下降时,心率会上升。这是身体适应新的血压之前的正常反应。这很可能是GLP-1受体激动剂导致静息心率升高的主要原因。

瑞达帕林似乎对血压有很强的抑制作用(以至于许多患者不得不停用所有降压药)。瑞达帕林一个非常常见的副作用是体位性低血压(快速站立时感到头晕)。这是血压短暂升高,同时心率也会相应加快。因此,人们会感觉心跳加速,但这并非静息心率,只要没有晕厥,就无需担心。随着身体逐渐适应新的血压,这种感觉也会逐渐消失。
 
zpped said:
此外,静息心率确实需要像健身手表这样的持续监测设备来追踪,任何低于100次/分的静息心率目前都没有已知的不良后果或因果关系。

每种GLP-1受体激动剂都会对静息心率产生影响,但由于每项研究的具体情况不同,因此很难进行比较。不过可以肯定的是,大多数服用GLP-1受体激动剂的人都会出现0-10次/分的暂时性静息心率升高。这种升高通常会随着时间推移而减弱。

此外,还有一种与血压相关的瞬时心率效应。当血压下降时,心率会上升。这是身体适应新的血压之前的正常反应。这很可能是GLP-1受体激动剂导致静息心率升高的主要原因。

瑞达帕林似乎对血压有很强的抑制作用(以至于许多患者不得不停用所有降压药)。瑞达帕林一个非常常见的副作用是体位性低血压(快速站立时感到头晕)。这是血压短暂升高,同时心率也会相应加快。因此,人们会感觉心跳加速,但这并非静息心率,只要没有晕厥,就无需担心。随着身体逐渐适应新的血压,这种感觉也会逐渐消失。
这就是我开始服用替泽帕肽时短暂经历的情况。大概持续了一周左右,也许更久。我的血压本来就比较低(我个子比较高),而且服用替泽帕肽后心率加快,快速起身时还会感到头晕。我当时很担心自己能不能坚持服用,但症状很快就消失了,我也就把这事儿忘了。
 
zpped said:
此外,静息心率确实需要像健身手表这样的连续监测器来跟踪,任何低于 100 的静息心率都没有已知的负面影响,也没有因果关系。
我超爱我的Galaxy Watch,它在这方面帮了我大忙。另外,使用GLP-1类药物时,平均心率增幅是多少?我目前只记录到心率增加了4bpm左右,但剂量非常低,所以🤷‍♂️
 
kaahhllll said:
I love my Galaxy Watch for this. Also, whats the average increase while using GLP1's? I'm only tracking an increase of about 4bpm, but super low dose so 🤷‍♂️
It's slightly dose dependent but not linearly. You might get up to 6bpm if you're already at 4.

Most people see 5+-2. It typically peaks after ~6 months and comes back down a bit.
 
Week 6:

I decided to continue at 0.5mg again, I'm still seeing good progress, though the rate has slowed. I am totally okay with it, as it is a healthier rate of loss!

I'm having no problem staying in a defecit. I eat when I am hungry, and stop when I am full. I'm no longer part of the clean plate club! I have broken that childhood eating disorder that my parents caused. "Don't waste food! Eat all your food, you want to be big and strong!" 🙄

I haven't been to the gym in about a week and a half, as i was going with my brother and he hurt himself. So I am not seeing any increase in muscle mass, but also not losing any. I am hoping to get back to the gym this week.

Down 2.8lbs this week, averaging 1300cal/day. Still feeling great every day. Getting much more restful sleep, have plenty of energy throughout the day. I am expecting to receive KLOW80, CJC-1295/IPA 5/5, and RT10 in the next week or so. I'm interested to see how the new peps affect my daily life.
 
Week seven:

Week six made me decide to titrate up. I am now at 1.0mg. My lowest recorded weight was 271.4, but came back up to 271.8. I forgot to weigh yesterday, but my tracker is as of this morning.

This entire process I have made sure to always eat when I am hungry. I'm not going to restrict myself and suffer silently, I'm going to eat, but track it for information purposes. I won't limit serving sizes, and if I finish a plate and I'm still hungry, I get more. I feel like if I didn't follow this behavior, I'd end up totally failing/binging/or giving up, or all three.

While I still lost a couple pounds this week, I was trending a lot higher in my calorie intake and gained a bit back.

First impressions after my dose last night, I've only eaten once today at about 600 calories and its been around 8 hours since then. I'm currently unable to find an appetite, nor do I feel hungry, so I will likely be forcing something into my face later as to not perish.

On a side note, I've added KLOW80, CP10, and Melanotan2 10mg to my stack. And started a pretty hefty vitamin and mineral stack as well. I'm feeling pretty damn good overall. A lot more energy, not needing as much sleep. My chronic knee and ankle pain has subsided (severed ACL, bucket handle tear in meniscus both on left knee, two ruptured ligaments in left ankle, all injuries range from 5-12 years old) and my acute shoulder injury is feeling less crunchy and gross.

Gym milestone:

Did legs yesterday and was able to rep my previous sessions failure weight on leg press. Previously failed at 3 reps at 478lbs, pushed out 2 sets of 10 last night. So definitely gaining muscle!

I've started using Samsung Health's medication tracker and it is pretty damn nice. I'd recommend it any day.
 
Keep in mind that Melanotan is a strong appetite suppressant.

Since you've started CJC/Ipa are you monitoring your igf-1 levels with blood work? Also, many people put on a little water weight with GH secretogues. It's not a bad thing but something to be aware of while tracking your fat loss.
 
zpped said:
Keep in mind that Melanotan is a strong appetite suppressant.

Since you've started CJC/Ipa are you monitoring your igf-1 levels with blood work? Also, many people put on a little water weight with GH secretogues. It's not a bad thing but something to be aware of while tracking your fat loss.
As far as MT2, today will be day 7 of 0.5mg/day and I will be moving to 0.5mg twice per week for maintenance. I am currently not feeling much appetite suppressant difference.

I am scheduling a lab visit in the next week or so, how frequently would you suggest getting labs done moving forward? That also may explain the plateau/gain over the last few days.
 
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