Day 3 of Selank and blown away

[datassica]

I've been injecting selank subq 500 mcg a day for about a week. One way I knew it worked was my scalp would start feeling a bunch of pressure shortly after injection.

I'm now realizing that pressure was probably DHT itch. Hair falling out at elevated levels despite taking finasteride. Either my anxiety levels weren't very bad or I didn't feel much of a difference. Gonna end my little lab project here.

 

[pddz9]

I've been injecting selank subq 500 mcg a day for about a week. One way I knew it worked was my scalp would start feeling a bunch of pressure shortly after injection.

I'm now realizing that pressure was probably DHT itch. Hair falling out at elevated levels despite taking finasteride. Either my anxiety levels weren't very bad or I didn't feel much of a difference. Gonna end my little lab project here.

Second this, i noticed it at work, i dont care much and also at home, i dont care about anything, i will stop using it, and will only use it for big events

 

[Chili777]

Second this, i noticed it at work, i dont care much and also at home, i dont care about anything, i will stop using it, and will only use it for big events

Did you scale back on the number of sprays? I think IN definitely gives you more dosage control as you can go up or down more easily, depending on response.

 

[pddz9]

Did you scale back on the number of sprays? I think IN definitely gives you more dosage control as you can go up or down more easily, depending on response.

I didn't used it this week because of the " i dont care" thing, but will try it like you mentioned, maybe 2 sprays instead of 4

 

[JoonyO]

the " i dont care" thing...

Neurobiological mechanisms of anhedonia - PMC

Anhedonia refers to the reduced ability to experience pleasure, and has been studied in different neuropsychiatrie disorders. Anhedonia is nevertheless considered as a core feature of major depressive disorder, according to DSM-IV criteria for major ...

pmc.ncbi.nlm.nih.gov

Not sure if this fits what you're saying is going on or not but you may find some useful info there.

 

[jw717us]

Did you scale back on the number of sprays? I think IN definitely gives you more dosage control as you can go up or down more easily, depending on response.

I'm going out on a limb and suggesting then you might not need it or benefit from it. In all the studies I've read I haven't see a direct relation to anhedonia or emotional blunting. In gross oversimplification it modulates triggering responses. For someone with high anxiety it modulates the trigger point so they are not immediately launched into fight or flight.

Some animal studies go as far as to show it can have a very mild anti-depressive effect in anhedonia implying it might even improve capacity for joy in a stressed system.

If you aren't having those issues then maybe this isn't the right tool to grab from the box?

 

[timj382]

That's so great !

I know about denial or just not knowing. I'm a medical doctor, and I didn't realize until I was 42 that I have anxiety. It just didn't occur to me, until my GP said it. I was like : no you are mistaken ! ' So what do you think those symptoms are ?' lol

But I also didn't realize, I'm ADD until 47 or 48, because I was always told : no one goes through medical school if they have ADD/ADHD. No one has those jobs and do those functions with ADD/ADHD. Well, I do have A LOT of co worker with that or autism. So common in my profession.

Anxiety is just one of the most common feelings / disorders, and it comes it so many forms and shapes.

I do have selank, and it shuts my brain up too.

When you say “it shuts my brain up” do you feel like there’s any blunting of mental sharpness or acuity?

 

[miss-sanne]

Got my NA selank and semax, so will try it out from tomorrow.

Excited !

I did have a pause in those peptides now for maybe 2 weeks.

My nasal spray wasn't working, so I overdosed Selank, because of hitting it too many times.

Oh man, I was like in a fog for a whole saturday.... don't do that again

 

[miss-sanne]

When you say “it shuts my brain up” do you feel like there’s any blunting of mental sharpness or acuity?

No, the opposite. Except when I overdosed. ;-)

I feel sharper, an example : I can keep the time better when I have patients in consultation. I can't really explain it, it just happens naturally. Like I have a maybe more 'normal brain function', not being disturbed all the time from my weird thoughts, lol.

 

[timj382]

No, the opposite. Except when I overdosed. ;-)

I feel sharper, an example : I can keep the time better when I have patients in consultation. I can't really explain it, it just happens naturally. Like I have a maybe more 'normal brain function', not being disturbed all the time from my weird thoughts, lol.

That's amazing. Thanks for sharing your experience.

Now I'm curious what you do that you have patients.

 

[miss-sanne]

That's amazing. Thanks for sharing your experience.

Now I'm curious what you do that you have patients.

Bonus info: it also helps me with my lag of 'executive function'. it's just easier for me to get the shit done at home fx.

I'm a GP, a medical doctor in Denmark. My everyday worklife is highly stressful and eventful, but with the two peptides, I come home and have maybe 15 % energy left to do stuff. Before these I was usually all wiped out.

It's become worse because I've gone into perimenopause.

Yes I should see a psychiatry about it. No, I don't really want to, because I don't like stimulants for myself.

 

[timj382]

Bonus info: it also helps me with my lag of 'executive function'. it's just easier for me to get the shit done at home fx.

I'm a GP, a medical doctor in Denmark. My everyday worklife is highly stressful and eventful, but with the two peptides, I come home and have maybe 15 % energy left to do stuff. Before these I was usually all wiped out.

It's become worse because I've gone into perimenopause.

Yes I should see a psychiatry about it. No, I don't really want to, because I don't like stimulants for myself.

It's encouraging to see a GP here.

Peptide sounds great.

My primary (our US word for it) prescribes Modafinil for me and it's been a game changer. Sounds like similar results. Maybe a bit more… turbo driven. Haha.

 

[miss-sanne]

It's encouraging to see a GP here.

Peptide sounds great.

My primary (our US word for it) prescribes Modafinil for me and it's been a game changer. Sounds like similar results. Maybe a bit more… turbo driven. Haha.

I did Modafinil daily, but after 7-10 days, I become depressed and anhedone.

So I only use it sometimes.

I would MAYBE want to try Atomoxetin, but right now I'm happy with peps.

 

[reyqaz]

This is so interesting and thank you for sharing the experience with Selank. Have Selank and Semax in line for research and wondering what's the route to go, Intranasal vs IM for OCD / Anxiety, overthinking

 

[FlowerFairy]

RS is on day three of research and in our experience this is gaming changing for my subject. They didn’t know they needed it. Apparently they have been in anxiety denial their entire life. A recent major life impact sent them into a spiral and we decided to try it just to see if it would help.

Three days ago we reconstituted 10mg with 10ml sterile saline in a 10ml nasal spray bottle that disburses .1ml per spray.At lunch time RS sprayed in each nostril and within the hour saw a notable shift in mindset. Constant background concerns faded away to a feeling of control and calm. RS will be trying 4 weeks on, 2 off for several cycles.

The past 3 days suggests that if someone has the right brain chemistry, it will have an immediate impact for. After the first day, RS learned they had been conning myself about things in my life. Apparently RS was a bit of an anxiety ridden mess that lied to myself that I was just always ready for the worst case. It was viewed as a good thing rather than a key sign of high anxiety. RS is high functioning and successful so they couldn’t possibly have anxiety, right??? Clearly wrong..

We just started the Peptide journey due to weight.. RS went from GLP1 via local through support via telemedicine. As we read we ended up going grey. After looking over a list of peptides we noticed comments about Selank for anxiety. We never….never…. bought into anxiety, at least in RS’s personal case. They brushed off a lot of signs and some friends suggesting it may be an issue. As we read more about Selank we realized that the people it helped in the Russian studies exhibited very similar symptoms to RS..

The more we read the more we realized RS was an absolute stereotype for anxiety. Every symptom showed could be traced back to childhood. That childhood experience primed RS for extreme anxiety and eventually cardiac issues in midlife despite being otherwise very healthy….weight aside and GLP1 helped dramatically there.

We decided to give it a shot….well a spray as it were. Within hours we noticed a fundamental difference to how RS was reacting. This is already too long so I’ll spare the details. I can only suggest if it has no, or minimal, effect on you then perhaps you are already wired normally and Selank isn’t the path for you.

I am genuinely optimistic for the remodeling effect exhibited in studies at this point, but the peace of mind it has already delivered is unbelievable. We are now looking at the possibility of adding Semax in the future.

Very good to hear! I’m trying to tell myself that I can tolerate nasal selank.. but my mom used to use some otc nasal spray on me as a child that smelled like male cat pee.. which left me very averse to ANYTHING nasal… so I’m having to work myself up to trying it..

 

[Chili777]

Very good to hear! I’m trying to tell myself that I can tolerate nasal selank.. but my mom used to use some otc nasal spray on me as a child that smelled like male cat pee.. which left me very averse to ANYTHING nasal… so I’m having to work myself up to trying it..

I don't think it has an odor, and I'm pretty sensitive to smells.

 

[FlowerFairy]

I don't think it has an odor, and I'm pretty sensitive to smells.

Most doesn’t.. but that childhood trauma is strong. I’m working on it..

 

[jw717us]

Very good to hear! I’m trying to tell myself that I can tolerate nasal selank.. but my mom used to use some otc nasal spray on me as a child that smelled like male cat pee.. which left me very averse to ANYTHING nasal… so I’m having to work myself up to trying it..

For my RS and RS's spouse there are no discernible odors or aftertastes. RS isn't sensitive but spouse is. Flonase for spouse was a disaster. For these it's no different than a saline spray.

 

[Chili777]

This is so interesting and thank you for sharing the experience with Selank. Have Selank and Semax in line for research and wondering what's the route to go, Intranasal vs IM for OCD / Anxiety, overthinking

If your goal is immediate effect and to be able dose flexibly, I think IN is the way to go. Bioavailability is higher (~90%) because IN bypasses the first-pass hepatic metabolism, which means your liver isn't breaking it down before it reaches your brain, so you can use less, and you're also placing the peptide more efficiently, closer to point of impact which is your brain and pituitary. All of this means the effects should be more acute. Also, I hope that was a typo and you mean Subq and not IM. Very, very few peptides are administered via IM.

 

[reyqaz]

If your goal is immediate effect and to be able dose flexibly, I think IN is the way to go. Bioavailability is higher (~90%) because IN bypasses the first-pass hepatic metabolism, which means your liver isn't breaking it down before it reaches your brain, so you can use less, and you're also placing the peptide more efficiently, closer to point of impact which is your brain and pituitary. All of this means the effects should be more acute. Also, I hope that was a typo and you mean Subq and not IM. Very, very few peptides are administered via IM.

Yep, I did mean subq, thanks for the info, much appreciated, any guide on creating this Intranasal saline spray? Thanks again.