Consideration: There is no "stopping" these meds.

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I’m on this for life no matter how long that may be I’m 78. Thinking about why I was over eating it boils down to that feeling after a meal that I’m not satisfied and I need to eat something else. It’s like an empty feeling that you need to fill but don’t know with what. So far tirz has kept that feeling at bay and it feels soooooo good I can eat a meal and no longer need to search for something else to satisfy the longing
 
Just going back to the original topic of this thread. I truly think this is the case. I have tried to stop reta a few times and I feel so off balance and my digestive system gets messed up. Reta helps make me feel normal. (even though it raises my resting heart rate).
 
50ShadesGreyMarket said:
If group 2 uses the peptides to develop healthy habits couldn’t it work? I joined a gym and got a personal trainer after having my youngest just so I could have a strict regimen to drop the last of the baby weight. Once I was back in shape I invested in a home setup and used the Peloton app.

If you use your time learning how to cook healthy meals and creating a workout routine you enjoy then it seems you would have a much better chance of keeping the weight off. I agree they’ll struggle, but I don’t see it as impossible. I’ve known people who lost weight unassisted and were able to keep it off. It’s not easy but if you change your lifestyle it’s not impossible.
Yeah nice dream. Maybe a select group, just like with any diet a select group will make lifestyle changes and keep their weight off forever. But look at the statistics for that. Not at all good, 80-95% of people gain the weight back and then some. I have eaten "real food" that I cooked myself and exercised my whole life and I was still fat. I already had a good lifestyle, what should have given me, so the story goes, a perfect weight using the calories in, calories out model, didn't. I've been chasing it for 40 years. This med somehow gives me the edge that I never had before. I'm not eating that much less than I was before, maybe the slowdown of the stomach emptying, and therefore keeping glucose regulated and insulin controlled, I don't know, but it works.
 
50ShadesGreyMarket said:
If group 2 uses the peptides to develop healthy habits couldn’t it work? I joined a gym and got a personal trainer after having my youngest just so I could have a strict regimen to drop the last of the baby weight. Once I was back in shape I invested in a home setup and used the Peloton app.

If you use your time learning how to cook healthy meals and creating a workout routine you enjoy then it seems you would have a much better chance of keeping the weight off. I agree they’ll struggle, but I don’t see it as impossible. I’ve known people who lost weight unassisted and were able to keep it off. It’s not easy but if you change your lifestyle it’s not impossible.
Do you have this same attitude with people who need BP medicine?
 
Nailedit said:
Yeah nice dream. Maybe a select group, just like with any diet a select group will make lifestyle changes and keep their weight off forever. But look at the statistics for that. Not at all good, 80-95% of people gain the weight back and then some. I have eaten "real food" that I cooked myself and exercised my whole life and I was still fat. I already had a good lifestyle, what should have given me, so the story goes, a perfect weight using the calories in, calories out model, didn't. I've been chasing it for 40 years. This med somehow gives me the edge that I never had before. I'm not eating that much less than I was before, maybe the slowdown of the stomach emptying, and therefore keeping glucose regulated and insulin controlled, I don't know, but it works.
This is really the crux of it and applies to virtually every chronic health condition (or anything in life, really): you can do everything 'right' and still have the issue. There's a very, very popular idea that if we only change this, or fix that, or become more disciplined or just .. figure something out we'll be able to solve once and for all whatever the problem was.

It's just not true though, at least for many things in life.
 
mlke6 said:
Do you have this same attitude with people who need BP medicine?

mlke6 said:
Do you have this same attitude with people who need BP medicine?
It’s not an attitude. If someone maintains disregulated blood pressure then they should continue to take medication. If their lifestyle habits and diet are able to get them to a place where their doctor thinks it a good idea to try stepping down to go their medication then I think it should be up to the patient and doctor. I had medical issues that required surgery in 2022 and my endocrinology team stepped me off of the medication I was on as it was no longer needed.

If someone absolutely wants to be on medication that’s between them and their doctor. I just think it’s ridiculous to insist everyone who’s ever taken a peptide protocol is stuck on it for life. I don’t agree with strangers telling one another they must continue to be on something until they die, it takes the autonomy away from the individual.
 
50ShadesGreyMarket said:
It’s not an attitude. If someone maintains disregulated blood pressure then they should continue to take medication. If their lifestyle habits and diet are able to get them to a place where their doctor thinks it a good idea to try stepping down to go their medication then I think it should be up to the patient and doctor. I had medical issues that required surgery in 2022 and my endocrinology team stepped me off of the medication I was on as it was no longer needed.

If someone absolutely wants to be on medication that’s between them and their doctor. I just think it’s ridiculous to insist everyone who’s ever taken a peptide protocol is stuck on it for life. I don’t agree with strangers telling one another they must continue to be on something until they die, it takes the autonomy away from the individual.

I believe the discussion was centered on whether people who lose weight on these drugs should generally be on them for life. You seem to be attacking something that no one advocated - that once a person takes these drugs that the person should necessarily be on the drugs for life. Just as a person may lose 100 pounds of weight without these medications and keep it off, it's also possible for someone to lose that 100 pounds with medications and keep it off without. It's just not that likely. There is research already existing showing that people who stop these medications usually regain the weight. We still don't know much about the exceptions - how frequent they are and what can be done to help someone succeed without the medication.
 
keangkong said:
I believe the discussion was centered on whether people who lose weight on these drugs should generally be on them for life. You seem to be attacking something that no one advocated - that once a person takes these drugs that the person should necessarily be on the drugs for life. Just as a person may lose 100 pounds of weight without these medications and keep it off, it's also possible for someone to lose that 100 pounds with medications and keep it off without. It's just not that likely. There is research already existing showing that people who stop these medications usually regain the weight. We still don't know much about the exceptions - how frequent they are and what can be done to help someone succeed without the medication.
I didn’t “attack” anything. If you want to be on any peptides the rest of your life then do so. If someone else doesn’t want to stay on them until they die then I think that is their prerogative. I work in biosciences and have seen plenty of adults make their own decisions. If you believe that you can’t live without something then that is true, but only for you. Not everyone has to live by your standards, that was the point I was making.
 
Having been a fitness instructor previously for many years and helped so many people lose weight I know how difficult it is for the majority of them to keep the weight from going back on. I have researched why this happens and it’s quite complicated and my brains too tired to explain it. So we do know for certain many people of glp1/2s will need to be using them for at least 10 years to help keep the weight off but what we don’t know is what the effects of this long usage will be on our bodies. Will we need higher and higher doses which may bring about issues or will we be able to keep at a dose which is suitable. It’s exciting as time goes on to discover more and more about we are subjecting our bodies to and the results we will get
 
Summer48 said:
Having been a fitness instructor previously for many years and helped so many people lose weight I know how difficult it is for the majority of them to keep the weight from going back on. I have researched why this happens and it’s quite complicated and my brains too tired to explain it. So we do know for certain many people of glp1/2s will need to be using them for at least 10 years to help keep the weight off but what we don’t know is what the effects of this long usage will be on our bodies. Will we need higher and higher doses which may bring about issues or will we be able to keep at a dose which is suitable. It’s exciting as time goes on to discover more and more about we are subjecting our bodies to and the results we will get
That’s why my original comment started with me posing a question. I later used the example of someone who can successfully change their lifestyle habits. I didn’t say “everyone should stop taking peptides”, I was very clear in the way I approached the subject. I’ve seen ‘My 600 lb Life’, I’m well aware there is a huge segment of our population that is full-blown addicted to gravy and fried foods and if they can’t have it they’ll become violent. My comment was in regards to those who use their time losing weight to make radical changes.

Regarding dosage, I think that is different for everyone. I know someone with diabetes who lost a significant amount of weight with Ozempic and has kept it off despite being on only 1mg for more than a few years now. I have been on .2mg Sema and .7mg Reta weekly since August. I have no plans to increase based on a schedule. However there are plenty of folks who titrate up to the maximum dosage as quickly as possible and no longer find it efficacious.
 
50ShadesGreyMarket said:
It’s not an attitude. If someone maintains disregulated blood pressure then they should continue to take medication. If their lifestyle habits and diet are able to get them to a place where their doctor thinks it a good idea to try stepping down to go their medication then I think it should be up to the patient and doctor. I had medical issues that required surgery in 2022 and my endocrinology team stepped me off of the medication I was on as it was no longer needed.

If someone absolutely wants to be on medication that’s between them and their doctor. I just think it’s ridiculous to insist everyone who’s ever taken a peptide protocol is stuck on it for life. I don’t agree with strangers telling one another they must continue to be on something until they die, it takes the autonomy away from the individual.
I have yet to see anyone claiming that we all MUST stay on GLP1s for life. What I have seen is some people saying that they are planning on it for themselves. I am in that group. We have accepted that it is what WE probably need. Sure inactivity and poor eating habits have played its part ... but there are many other causes of obesity and for most of us we are dealing with MULTIPLE causes.

Frankly .. at the end f the day what we do is none of your business. Just like you don't want anyone telling you that you MUST be on a drug for life .. YOU don't get to tell anyone that they shouldn't continue taking something that is helping them. Be it real or imagined.
 
MsGizmo said:
I have yet to see anyone claiming that we all MUST stay on GLP1s for life. What I have seen is some people saying that they are planning on it for themselves. I am in that group. We have accepted that it is what WE probably need. Sure inactivity and poor eating habits have played its part ... but there are many other causes of obesity and for most of us we are dealing with MULTIPLE causes.

Frankly .. at the end f the day what we do is none of your business. Just like you don't want anyone telling you that you MUST be on a drug for life .. YOU don't get to tell anyone that they shouldn't continue taking something that is helping them. Be it real or imagined.
If you read my original comment and the reply that implied I was saying something I wasn’t it puts it in context. I think each person has their own journey with peptides, for some that will be lifelong but for others, I don’t think that has to be the case. I posed that scenario in my first response to the thread. I never said anybody should or shouldn’t do anything. I was the one pushing back against the “must be on forever” narrative. I think it’s up to the individual.

In the real world, if you insist someone can or cannot achieve a goal when you know nothing about them they would probably tell you to go F*** yourself. Most folks don’t put up with that.
 
This month is my 25th anniversary of HAVING MY LIFE BACK!!

Over 25 years ago, I was diagnosed with a serious medical issue that will remain private. Multiple hospital stays. Doc was supportive. Then Doc retired, new doc took over my care. New Doc decided to change my meds based on some recent studies. Yeah whatever.

But I started getting better .

And after about 3 months, I was back to doing most of the things I was doing before I was diagnosed!! My disorder is contained!! I FINALLY HAD MY LIFE BACK!!

I still have the disorder. The meds are (still) expensive. They are sometimes a PITA to get, yes. even with a completely legal above-board Rx. Rare disorders == rare medication. It's a very not-fun thing to deal with. BUT I HAVE MY LIFE BACK!!

A longtime, dear friend of mine grew up in India. They meant well when they said "I pray that someday you don't have to take those pills."

I said, I don't. I thank the heavens that I HAVE MY LIFE BACK!!!!

I don't like medication. I generally resist taking it. Aside from this particular treatment, the only other rx I took was for hypertension -- my blood pressure is too high, I'm fat, I'm getting older, and I don't exercise enough.

And now, I have GLP-1 in the mix. This is just my first week. But now that I have life without food noise? This may be another reason to shout.

I guess what I'm taking a very long time to say is -- a med for life is OK with me, if it means I have more of my life back. I am in my 50s. The number of meds I am taking is unlikely to go down anytime soon.
 
4StrandKnot said:
This month is my 25th anniversary of HAVING MY LIFE BACK!!

Over 25 years ago, I was diagnosed with a serious medical issue that will remain private. Multiple hospital stays. Doc was supportive. Then Doc retired, new doc took over my care. New Doc decided to change my meds based on some recent studies. Yeah whatever.

But I started getting better .

And after about 3 months, I was back to doing most of the things I was doing before I was diagnosed!! My disorder is contained!! I FINALLY HAD MY LIFE BACK!!

I still have the disorder. The meds are (still) expensive. They are sometimes a PITA to get, yes. even with a completely legal above-board Rx. Rare disorders == rare medication. It's a very not-fun thing to deal with. BUT I HAVE MY LIFE BACK!!

A longtime, dear friend of mine grew up in India. They meant well when they said "I pray that someday you don't have to take those pills."

I said, I don't. I thank the heavens that I HAVE MY LIFE BACK!!!!

I don't like medication. I generally resist taking it. Aside from this particular treatment, the only other rx I took was for hypertension -- my blood pressure is too high, I'm fat, I'm getting older, and I don't exercise enough.

And now, I have GLP-1 in the mix. This is just my first week. But now that I have life without food noise? This may be another reason to shout.

I guess what I'm taking a very long time to say is -- a med for life is OK with me, if it means I have more of my life back. I am in my 50s. The number of meds I am taking is unlikely to go down anytime soon.
One thing that I've noticed over the years is that people without an illness are often the one most critical of those who have one. Thin people complain the loudest about GLP1 drugs while at the same time criticize us for being fat in the first place.
 
I’ve appreciated the engagement in this discussion. It’s been a good read so far. I agree with some bits and disagree with others. I don’t dismiss the bits I disagree with off hand, and someday I may find that in fact I have changed my mind and see them as truth! We all want our cake and to eat it too. That’s human nature.

Sometimes the body heals with time and support, like a cast on a broken limb. Other times it needs ongoing help, like eyeglasses or contacts. In some cases a permanent fix exists, such as eye surgery or joint replacement. Most of these interventions don’t return you to brand-new condition, but they usually leave you better off than doing nothing. And when possible, many people would rather put in the effort, make changes, and build habits that let them live well with less medical intervention.

It’s important for each of us to take responsibility for our own health. Professionals, medications, circumstances, and tools all inform our choices, but they don’t replace them. Handing those choices off completely is an illusion. You remain in the driver’s seat whether you acknowledge it or not, and you are the one who lives with the outcome. When you use outside input to guide your path, the responsibility still rests with you.

Can we step off these peptides and keep the progress on our own? I hope so. It may not be possible for everyone. That reality shouldn’t stop anyone from trying. Refusing to try closes the door on growth before it begins. At the same time, if continued therapy ends up being the right path, that isn’t discouraging or shameful. It’s simply information about what your body needs. Other people’s successes or decisions don’t threaten your path. They offer data, perspective, and possible ideas for the next step.

Your path is unique. Your body carries its own history, and potential. It deserves honesty rather than judgement. If long-term therapy remains part of your current reality, make it a deliberate choice to keep moving forward. If you’re able to taper off and hold your gains, that’s progress too. What matters is acting with intention and working within the reality you live in. When the road bends, turning too early is as disastrous as not turning at all. Progress is personal, and it’s only real when you claim it.
 
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