Congress introduce bill to restrict manufacture of GLP1s.

[Foggy-Hollow]

This summer with the FDA to be "screening" all FDA-regulated packages starting July 9th, instead of just packages of a certain declared value, I was thinking that too was a possibility, even by now. But prices have never gone up before, ever, that I know of. Only down.

My favorite US warehouser is drifting up. Sigh. Found their presales in Oct and snagged a kit of T30 at import prices. The last month those have been 150% import.

I’m hoping it’s just a holiday spike. Who knows. Maybe the profits will be too sweet to wean off from.

 

[Calm Logic]

For GLPs, my ideal are smaller-mg vials (due to stacking with other GLPs) that are pre-tested by a domestic Uther reseller like PWGrove, which recently sold out of R20 for $135.

 

[Foggy-Hollow]

if zepbound became available to me and all I had to do was pay the $25 co-pay per month, I would seriously consider switching away from my current sema/reta combo.

With 70% of Americans being overweight or obese, there’s a whole lot of people that would.

If prices dropped to $25/mo, I think demand would outstrip production. Maybe I underestimate China’s ability to adapt and supply. $100 is often quipped online as a buy-in point.

Would you give up control over the dose? I’m not sure I could. After being shoehorned into standard doses since getting on mood meds in 2012 it’s been refreshing to have some say over step size and “just stick out the side effects” mentality.

 

[ThatNextGril]

Well, as someone who is stocked for about 2.5 years on her beloved tirz, I just went ahead and did a pre-order for reta 24. I've not used reta yet, and am hoping tirz keeps tirzing for me, but I'm sort of thinking it might be good to have a stash of the reta in the event I do plan to make the switch next year.

Funny enough, I went just to see if it was still available for preorder and it was still in stock as I mulled it over. This thread made me pop over there in the last 20 mins to make the purchase and I noticed the GLP names were all changed. They used to call out tirzepatide, semaglutite and retatrutude in full on the bottle images and listings, but they are now letter coded. Checked TG and sure enough they posted a pinned comment about the change to stay ahead of potential future regulatory requirements. Just thought it was interesting that they are also keeping a close eye on this news topic.

 

[Garbo]

I did a search and cannot find the text of the actual bill online or in Congresss.gov

Maybe all the file clerks got laid off.

 

[MsGizmo]

With 70% of Americans being overweight or obese, there’s a whole lot of people that would.

If prices dropped to $25/mo, I think demand would outstrip production. Maybe I underestimate China’s ability to adapt and supply. $100 is often quipped online as a buy-in point.

Would you give up control over the dose? I’m not sure I could. After being shoehorned into standard doses since getting on mood meds in 2012 it’s been refreshing to have some say over step size and “just stick out the side effects” mentality.

Well ... I only said I would consider it

As for the supply ... they could totally do it. The only real choke point on the supply chain was the plastic injection pens. Easily solved by giving us syringes and the vials. Lilly is already doing that.

 

[RadicalCrimson]

Alpha Omega Peptides (who I used to buy from before getting plugged into sites like this) sent an email this morning saying that due to regulatory changes, they’re getting out of all GLPs and marked their stock down 30%. (Of course that still makes their single vials just a little more than a whole kit from China.) So I agree, more people will be looking for supplies from other sources.

Kimera Chems sent the same email:

We’re reaching out with an important update regarding our product catalog.

Due to ongoing changes in the regulatory and compliance landscape, Kimera Chems will be discontinuing all GLP-class products from our catalog.

What’s changing

All GLP-class products will be removed from our website on January 1st, or sooner if inventory sells out.

This includes;

GLP-SM

GLP/GIP-TZ

GLP/GIP/GLU-RT

Cagrilintide

Cagri/GLP-SM

Cagri/GLP-RT

After removal, these items will no longer be available for purchase.

 

[RadicalCrimson]

I just saw a single vial of T100 for $268.

I just did a group buy of Uther T100 for $220. For 10 vials.

That's 12 times less.

Update: The email said $268, but the website says $291.

$218.25 if you buy 3+, though. What a bargain!

 

[Calm Logic]

I just did a group buy of Uther T100 for $220. For 10 vials.

That's 12 times less.

Yes, at PWGrove for $205 plus $15 flat shipping. It will be in small 3 mL vials like everything else.

 

[d0se1]

I got an email from Skye today. Looks like several are throwing in the towel.

 

[Calm Logic]

They seem to be really over-reacting.

Not knowing anything, I would venture that sales were already dropping (for the overpriced/ripoff resellers), so risk tolerance was lessening. Or someone they all know was busted or some other insider info.

 

[tubby]

They seem to be really over-reacting.

Not knowing anything, I would venture that sales were already dropping, so risk tolerance was lessening. Or someone they all know was busted or some other insider info.

I mean there are two ways the soon to be new law plays out:

Either it's written narrowly such that compounding pharmacies only get in trouble if they sell "counterfeit" products that are fully reconstituted OR they decide that the law applies to anyone selling "counterfeit" GLP1-related products and nail domestic sellers with running an unlicensed pharmacy (and whatever additional charges might apply there) while they're at it.

If I was in their shoes I wouldn't want to take the gamble on which way it plays out. Not sure how old you are, but it feels strangely reminiscent of back in the day when the RIAA went after Napster (and other file sharing services).

If 5% to 10% of users are going through non-pharma channels, they probably wouldn't care, but when it's gotten to the point where Tiktok users are actively encouraging Lilly's potential customer base to buy elsewhere, pharma is going to put their full weight behind crushing the non-official US supply chain to whatever extent they're able to.

 

[Calm Logic]

If I was in their shoes I wouldn't want to take the gamble on which way it plays out. Not sure how old you are, but it feels strangely reminiscent of back in the day when the RIAA went after Napster (and other file sharing services).

If 5% to 10% of users are going through non-pharma channels, they probably wouldn't care, but when it's gotten to the point where Tiktok users are actively encouraging Lilly's potential customer base to buy elsewhere, pharma is going to put their full weight behind crushing the non-official US supply chain to whatever extent they're able to.

They have always been taking risks, so why stop exactly now? As others have said here and elsewhere, first, there has to be a law. Then it has to be implemented. Congress is slow, the FDA is underfunded, etc. So there is more to the story.

Selling sema at $10 a mg is sleazy anyway (as with Kimera Chems for a vial of sema 5 mg), so good riddance, though GLPs will be back by some of these guys who are just temporarily on the bangwagon to create marketing buzz/urgency.

These guys are all with public websites, so Cain will just get more business in the meantime, including maybe even his EZPeptides site with reta 48-mg kits for over $1800. Until Cain ever gets busted, wisely retires, or stops having a very public website, Cain seems invincible, though so did Napster. But one way the Napster situation was different was that every young person was using it.

 

[Waclive]

I'm not even using a GLP-1 yet and this makes me want to buy and hold on to a large supply right now.

 

[Calm Logic]

For the most part, it's a fictional crisis to extract more from the vulnerable by the greediest people in grey:



It's an excuse to increase demand and temporarily lower prices. More people are becoming informed that these vendors charge same/more than some newbie-friendly compounding pharmacies.

Sooner than later, orfoglipron pills by Elli Lilly will be out for $150 per month self-pay, which is another stressor for these sleazy vendors:

 

[Jellybelly54]

Here is the six page bill. Just another bill to protect Eli Lilly and Novo Nordisk. Send a message to your congressman asking them to vote against it. That’s all you can do .

https://d12t4t5x3vyizu.cloudfront.net/yakym.house.gov/uploads/2025/12/SAFE-Drug-Act-Final-Bill-Text.pdf

 

[Waclive]

Here is the six page bill. Just another bill to protect Eli Lilly and Novo Nordisk. Send a message to your congressman asking them to vote against it. That’s all you can do .

https://d12t4t5x3vyizu.cloudfront.net/yakym.house.gov/uploads/2025/12/SAFE-Drug-Act-Final-Bill-Text.pdf

Sourcing alternatively is probably the most effective thing to do, sadly. Does anyone remember when congress worked for the people? Meh, me either.

 

[keangkong]

Have you guys seen the below video on this?

View: https://www.youtube.com/watch?v=1aYpPTDqeLM&t=13s

https://www.whitehouse.gov/fact-she...-favored-nation-pricing-to-american-patients/

My quick read of the proposed bill mentioned in this thread is that it only applies to compounding pharmacies that are selling their stuff out of state. It may be mean that people who get compounded GLP-1 drugs will have to get them in-state.

 

[yrrdead]

Sourcing alternatively is probably the most effective thing to do, sadly. Does anyone remember when congress worked for the people? Meh, me either.

Well you work for who pays you , same with congress. Unfortunately their paycheck from the people is dwarfed by lobbying/corporate dollars.

Don't worry as Citizens United showed us , Corporations are people too.

 

[Waclive]

Well you work for who pays you , same with congress. Unfortunately their paycheck from the people is dwarfed by lobbying/corporate dollars.

Don't worry as Citizens United showed us , Corporations are people too.

The good ole American conflict of interest.