bolstering cortisone guided injection with Wolverine Stack or GH agonists?

[nwark]

Having a guided cortisone shot to deal with a spine issue. Wondering if anyone has any research data or anecdotes on bolstering effectiveness of cortisone shots with peptides such as TB500/BP157 or any GH agonists? Or is it best to just let the cortisone do its thing?

 

[yrrdead]

Having a guided cortisone shot to deal with a spine issue. Wondering if anyone has any research data or anecdotes on bolstering effectiveness of cortisone shots with peptides such as TB500/BP157 or any GH agonists? Or is it best to just let the cortisone do its thing?

While cortisone can reduce inflammation and provide some needed relief, it is a temporary solution at best. At least that has been my understanding. Whilst a combination of BPC/TB and maybe KPV would seem to be a superior treatment.

*not a dr, listen to professionals not idiots on the internet.

 

[lessthanhalf]

I do not see any possibility of getting a doctor to inject something they have not prescribed, does not have guaranteed sterility, does not have solid science behind it and is not registered for therapeutic use in Australia. If something went wrong they would not have a leg to stand on in court trying to defend against malpractice. It might be bad enough to qualify as criminal negligence or cause them to lose their medical license. The uncertain sterility issue alone is an extremely good reason to never inject anything peptide like anywhere except under the skin, unless it came from a proper pharmacy company with standards and inspections etc. If you get a small infection just under the skin from a few bugs, it is very unlikely to kill you, the same near the spine is an incredibly serious infection, that could kill, cause permanent damage or at least require weeks of intravenous antibiotics in hospital.

I personally do not think those peptides ( TB500/BP157 ) have good evidence that they work, are minimally if at all tested in humans, despite everyone online saying how great they are. If you want to use them - orally or subcutaneously , if s/c somewhere sensible like the stomach, nowhere near any joints. HGH probably does improve healing but also has side effects. Doctors do not use it for faster healing as the risk to benefit ratio is not thought to be worthwhile.

 

[RubbaDubba1]

Having a guided cortisone shot to deal with a spine issue. Wondering if anyone has any research data or anecdotes on bolstering effectiveness of cortisone shots with peptides such as TB500/BP157 or any GH agonists? Or is it best to just let the cortisone do its thing?

I've had over 100 shots of Cortisone in my life to this point, if it's in the right spot and stays within the joint (so to speak) If your diabetic, watch your blood sugar! It can definitely help for a period and even a year for me in some cases. Cortisone is great, in that it provides fast relief vs peptides and regenerative medicine Prolotherapy, PRP, Stem cells, etc. It's when you start to get repeated injections, more frequently and over a few years it will start to break down soft tissue (Cartlidge) Then your Arthritis, bone on bone and or Spondylosis (Bones fuse) and the pain really starts to go up.

Normally insurance covers a cortisone injection for 45-90 days, you could cancel it and run a course of BPC/TB and see if it helps. If not, then go back and get the Cortisone shot. But, personally I would go ahead with the Cortisone shot, see what/if level of relief you get and hopefully it helps. When you feel the Cortisone wearing off (you will) and you start to get close to when you 1st considered a cortisone shot. Then run your course of BPC/TB, try it then and see what that does for you. Don't know about GH for spine, run them all separately to see what works doesn't. Some people are non responders to peps or it's awesome. It's mild for me, but enough to where I will stay on it, as I need all the help I can get with my Arthritic load, as I can't take Nsaids. Just had my shoulder operated on: [archived internal link]

Good luck

 

[yrrdead]

I do not see any possibility of getting a doctor to inject something they have not prescribed, does not have guaranteed sterility, does not have solid science behind it and is not registered for therapeutic use in Australia. If something went wrong they would not have a leg to stand on in court trying to defend against malpractice. It might be bad enough to qualify as criminal negligence or cause them to lose their medical license. The uncertain sterility issue alone is an extremely good reason to never inject anything peptide like anywhere except under the skin, unless it came from a proper pharmacy company with standards and inspections etc. If you get a small infection just under the skin from a few bugs, it is very unlikely to kill you, the same near the spine is an incredibly serious infection, that could kill, cause permanent damage or at least require weeks of intravenous antibiotics in hospital.

I personally do not think those peptides ( TB500/BP157 ) have good evidence that they work, are minimally if at all tested in humans, despite everyone online saying how great they are. If you want to use them - orally or subcutaneously , if s/c somewhere sensible like the stomach, nowhere near any joints. HGH probably does improve healing but also has side effects. Doctors do not use it for faster healing as the risk to benefit ratio is not thought to be worthwhile.

I didn't think that I even implied injecting peptides into a joint. Nor did the OP.

I was mainly trying to highlight how little good cortisone does. In addition to causing degeneration in some studies after only a single injection.

 

[Jfrick11]

Having a guided cortisone shot to deal with a spine issue. Wondering if anyone has any research data or anecdotes on bolstering effectiveness of cortisone shots with peptides such as TB500/BP157 or any GH agonists? Or is it best to just let the cortisone do its thing?

I would actually be cautious of adding either with cortisone.

The steroid is an anti-inflammatory that's meant to calm nerve irritation and swelling. It's not really about healing tissue, it's more about symptom control...reducing inflammation so the body and (therapy) can work better.

BPC-157 / TB-500 is used to increase blood flow and stimulate angiogenesis to promote tissue repair and reduce inflammation.

So the flag issue I see is that the mechanisms may actually conflict.

Cortisone suppressed inflammation and some healing signals

BPC/TB stimulate healing and inflammatory pathways, so theoretically, you could be working against the steroids mechanism.

The other thing is BPC/TB is more known for soft tissue injuries, (tendons, muscles...so if it's that you may be on to something), but not disc compression issues, disc bulging, nerve issues or really spine in general. Here timing would matter so you're not working against each other.

GH, kind of similar unless it's a soft tissue injury like instability, weak supporting muscles of chronic strain. But timing here would be really important here too because Cortisone is catabolic (it breaks down tissue and suppresses repair signals, while GH is anabolic (it builds tissues).

**So if you use them together... you’re basically hitting the gas and the brake at the same time

 

[nwark]

Much appreciate the discussion, it is why i asked the question. My issue is actually a synovial cyst at the facet joint. Neurosurgeon wants me to have the guided shot before moving to surgical removal should it be unsuccessful (he rates it a 50% chance.)

The potential bolstering is not his idea, but me wondering if there is anything I can do to help improve the 50 50 to 60 40 or better. The feedback here suggests maybe no.

 

[lessthanhalf]

Yes, Sorry I did misread the original post.