Smiter
New member
You're welcome but whats TIL?bogardbilla said:
Best peptide for body recomposition?
- Thread starter RanHerOver
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bogardbilla
GLP-1 Apprentice
"Today I Learned" - I wasn't aware such a peptide existed.Smiter said:
Smiter said:
Hoooooold up. Hold up. Wait.
So, in terms of muscle gain and/or retention, PEG-MGF is the best?
What about HGH, IGF-1 LR3, IGF-1 DES, CJC/IPA? I'm assuming CJC/IPA ranks last, but what about the others??
bogardbilla
GLP-1 Apprentice
Seems like they complement the PEG-MGF:dancs said:
https://swolverine.com/blogs/blog/peg-mgf-for-beginners-muscle-repair-dosing-and-stacking-guide
There are two elements to body recomp; body fat reduction and building muscle. No peptide will build your muscle for you, so just focusing on fat reduction: GLP1s and whatever helps you either exert more energy or eat less - and this could be different for everyone. But if you're not on HGH, you are missing out. Tesa would work, but the ROI compared to HGH is laughable. CJC/Ipa are not even in the same league.
Smiter
New member
Beat me to it.Dos-Dox said:TIL what TIL means!
One of my main goals is to avoid HGH as much as Possible. Yes, many folks use HGH for its anabolic Profile. The hyPerglycemia and insulin resistance caused by HGH may be mitigated by the GLPs. Nonetheless, I do NOT want to take any risk with insulin resistance as an ex-diabetic. Similarly, the acromegaly-like symPtoms of increased organ size, along with water retention that I'm Prone to, joint irregularities, etc., make HGH appear very ugly to me. It literally murders my hard-on.miameow said:
Besides, the OP's question was about the best Peptide for body recomPosition. I decided to answer this by taking quality of recomPosition as the defining metric, as opposed to quantity. This is obviously a Personal choice, and despite the irksome TLDR effect, I will elaborate.
My understanding of all the anabolics out there, including TRT, HGH, AAS, etc., is that they work primarily by enhancing IGF-1 signaling, and in the case of AAS, it triggers androgen receptor signaling by triggering gene expression in myocytes. It also works on muscle satellite cell Progression.
I had a sleeve gastrectomy in 2022 and by 2025, the resulting weight loss made me lose all the hard-earned muscle I had. In June, I went to India and had a stem-cell + PRP treatment for my left rotator cuff tears and left bicePs tendinosis. While I was recuperating, I came to know that the Indian national armwrestling tournament was being held in the first week of July. Now, I hadn't taken Part in armwrestling since 2016, and was in no condition to participate in even a local tournament. In mid-June, I decided to "fvck it" and take Part. My competition weight prior to 2016 was 135 kg. I was 112kgs in 2025 June.
Now, I know that the BPC-TB-500 stack is called Wolverine because of the Marvel character's legendary healing skill. But, highly educated and intelligent folks will know that there are others who have a greater healing and regeneration ability such as the Incredible Hulk.
Tangent explored aside, I started to stack my Wolverine with PEG MGF on 14th June and started training. I was bicep curling 20lb dumbbells with difficulty. I used to do it with Eighty-five lb dumbbells. Anyway, in July I got 3rd in the Masters suPerheavyweight category weighing 115kilograms. That's 254lbs for the metrically challenged folks.
Anyway, the key Part is that my 3 weeks of PEG MGF usage finished and I returned to being a waste without strength. Then in Feb of this year I restarted working out in the Golds gym here with the same 20lb dumbbell. I was doing barbell curls with 40lbs. I started taking Retatrutide on May 1st. Before that, I did 3 rePs of cheat curls on the 110 lbs barbell and 6 rePs of Proper curls on the 100lb barbell. This time I was taking BPC-TB500 and no PEG MGF. Obviously, it is due to muscle memory.
This is where muscle satellite/stem cells come into Play. While testosterone or AAS boosts this, PEG MGF targets this function. It increases the amount of satellite cells transcribed into muscle, permanently increasing the number of myonuclei in muscle cells. I won't go into details about why that is a humongous advantage [this is already too long].
In terms of body recomposition, I consider sublime quality to be permanent increases in myonuclei, sarcomere count, and tendon strength via Young's modulus, not cross-sectional area.
And this is why I chose PEG MGF as the best 'PePtide'.
I would stack it with BPC, TB-500 for local subq shots.
Reasoning:- After GLP-1-derived weight loss, when I would have to gain muscle, I want to minimize the fat and water retention that will accompany the bulking Phase. I also want to permanently increase my muscle strength, density, and tendon strength.
For all the enlightened members here, I have named the BpC-TB500-pEG MGF stack as the Doomsday stack- after the DC comics Superman-killer. You guys know his main superpower -[psst...evolution...sshhh!]
lastresort
GLP-1 Enthusiast
Good point.Smiter said:
Taking one poison only to counter it with another, unless therapeutically necessary (very rare), is a waste of money and an unnecessary gambling.
Smiter
New member
precisely, and as a strategist, I'm for maximal gain for minimal effort. And when using a tool for one of its downstream effects, I would rather use the tool that specifically provides the target effect. No hepatotoxicity, no messing with endogenous test, estrogen, GH, IGF levels.lastresort said:
DustAndDignity
GLP-1 Apprentice
I’m a huge fan of Tesa. I’m currently running it and it’ll probably stay a staple for me moving forward. I’ll forever lean biased toward it being superior to CJC-1295.CMA Pooky said:
That said… I wouldn’t be so quick to completely write CJC off either.
As already mentioned, Tesa was specifically studied for reducing visceral fat in individuals with HIV associated lipodystrophy. On average those individuals were carrying a much higher level of visceral fat than your average Joe/Jill looking for body composition improvements.
I don’t believe we’ve seen that same type of study done with CJC-1295, so I’m not sure it’s really a clean apples to apples comparison yet. Especially when people are stacking it with Ipa.
I personly wouldn’t be surprised at all if you could see pretty comparable outcomes over time depending on the individual, diet, training, dosing consistency, starting BF%, etc.
I haven't used anything other than reta, and I don't know if I'm missing anything, but what I've noticed is I've been losing 1 - 1.5 lbs per week since I started, four weeks ago, and I've seen an insane body recomposition. I've gained so much muscle and lost so much fat. But if there are any other peptides, I'm not sure it would even help because At the end of the day, for body recomposition, you gotta be gaining muscle and losing fat at the same time, which you can do easily, and especially with reta. So what you can do is just find your maintenance dosage and maintain your body weight, or even go on a decent calorie deficit. So long as you're eating enough protein and getting in enough carbohydrates for recovery, then you should easily be able to body recomp nicely. Tracking your number on the scale and calories helps a lot as well so you can fine tune and adjust things.
lastresort
GLP-1 Enthusiast
one reason that adipotide clinical study was halted in phase 1 was potential kidney damages.FlowerFairy said:
Did you ever check your kidney markers?
FlowerFairy
GLP-1 Enthusiast
I was getting regular labs. My kidney markers were normal. This is why I was super careful to calculate the dose based on my weight. I was using slightly less than the “safe max dose.”lastresort said:
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