Are reta and other weight loss drugs meant to be long term use? Whats it like coming off them?

[zpped]

Hey zpped, i wanted to message you this but dont think i can cuz how new my account is.

I understand my permissions are a bit limited but can i make a post asking about peoples opinions on endotoxin testing and how essential it is? and ask for peoples opinion on MZ biolabs and to see if they have other budget but reliable options?

I finally got my peptides a couple days away from me (from a board sponsor) and im hoping to send for testing pretty much immediately since the vial im currently using is already a month old and figure i got another 2-4 weeks on it before i need a new vial. So want to get this done asap so i can start using the new stuff asap too. im set on testing for ID/Purity and content but that endotoxin is not cheap....so wondering if folks see it as a must since from my understanding you wont IMMEDIATELY die (LOL) from endotoxins

You can ask about endotoxin testing in an apropiate place. Or just go read the big thread about it and you'll get a lot opinions already.

You can't ask about sources until you're off of probation.

 

[indolent]

asking about peoples opinions on endotoxin testing and how essential it is? and ask for peoples opinion on

your best bets are two-fold:

search this very website for endotoxin testing and find lots of opinions

search this very website for group testing, learn about and join one or more of the (external) third-party group testing platforms, and see if your particular batch of the peptides you ordered has already been tested by a group. Give back & pay forward on those testing groups! Never trust vendor-provided CoAs.

By using search (and, BTW, the table of contents structure linked in the big logo at the top), you can avoid treating the boards (as many do) as a one-to-one chatbot. Which I don't mean as an insult, just a perspective.

 

[bockscar]

You can ask about endotoxin testing in an apropiate place. Or just go read the big thread about it and you'll get a lot opinions already.

You can't ask about sources until you're off of probation.

gotcha and thanks for the quick reply. im just gonna bite the bullet and do it cuz my probation doesnt let me in the testing sub forum yet . Ive heard cases both ways that made sense to me so im just gonna do it.

 

[FamousGoodkitty]

One thing to keep in mind - Obesity is a chronic disease. Sometimes a chronic disease requires medication for life in order to keep the chronic disease under control. Mine does, and thus I will be on this for life. In maintenance, yes, but still - needing to keep the chronic disease under control.

 

[Vriende]

... Or just go read the big thread about it and you'll get a lot opinions already...

... By using search (and, BTW, the table of contents structure linked in the big logo at the top), you can avoid treating the boards (as many do) as a one-to-one chatbot. Which I don't mean as an insult, just a perspective.

Click to expand...

@indolent -- Thanks! I finally get it! I have been puzzled for months about the naive or pesky questions we see here over and over

-- you have opened my eyes -- people treat this forum like a one-to-one chatbot !

For those of us who have used the internet for at least a decade -- we have learned to search.

Perhaps there is a whole new generation of people coming on board who just turn to chatbots?

Do we need to provide a "Search 101" tutorial ;-) Is it a lost art?

 

[bockscar]

@indolent -- Thanks! I finally get it! I have been puzzled for months about the naive or pesky questions we see here over and over

-- you have opened my eyes -- people treat this forum like a one-to-one chatbot !

For those of us who have used the internet for at least a decade -- we have learned to search.

Perhaps there is a whole new generation of people coming on board who just turn to chatbots?

Do we need to provide a "Search 101" tutorial ;-) Is it a lost art?

you know you all can just scroll past right? im not sure your crusade will be as fruitful as you all might hope.

 

[zpped]

you know you all can just scroll past right? im not sure your crusade will be as fruitful as you all might hope.

Nah, they are right. I was feeling generous and answered your question. But this wasn't the right place for it and all your answers were easily available if you'd just looked around.

 

[bockscar]

Nah, they are right. I was feeling generous and answered your question. But this wasn't the right place for it and all your answers were easily available if you'd just looked around.

Ive used the search function. I see no table of contents that hes talking about. I cant comment or message anyone in the testing groups. How do I do half of what he is saying when its not currently possible due to my account status?

 

[indolent]

I see no table of contents that hes talking about.

tap the big GLP1forum banner at the top of any page

 

[bockscar]

Thank you zpped and/or FamousGoodKitty

 

[Shittersfull]

I'm so glad I didn't realize that glps should be a lifetime decision. If I would have known that, I would not have tried reta. I just don't like the idea of being on something forever. Thank God of my ignorance. Reta for wieght loss, probably tirz for maintenance. Glps probably best decision of my life. Now I'm not going to be on a bunch of meds for my entire life. Just joined a gb for 3 kits of r and 4 kits of t. That's about a decade of health right in front of me. Costs less than a cup of coffee a week.

 

[lessthanhalf]

One fairly simple way to work out if staying on GLP drugs long term is a good idea is to use an online calculator or a doctors visit to get an estimate of your absolute cardiovascular risk. The largest risk factor by far is age, so results are going to be heavily influenced by that. But if you know your age, blood pressure and lipids, smoking and family history and ideally blood sugar, that should be all you need. If absolute cardiovascular risk is high, then staying on them is definitely a good idea, and probably high rather than low doses if tolerated. If younger then it is less critical, as you are just a lot less likely to have heart attacks or strokes in your 30's or 40 's as compared to people in their 60's or 70's, but you can be guided by relative risk for age, if very high, then staying on GLP's is also likely a good idea, with the aim of not having those problems as you get older.

Just for example, If your absolute risk is 20% over the next 10 years, which is not that unlikely if above 50 and obese with metabolic syndrome, then GLP's reduce that down to about 14%, and you would also likely need statins etc with that level of risk, overall you can likely drop those odds in half. Reducing the chances of a heart attack by 50% over the next 10 years, or changing the odds from 1/5 to 1/10 is a lot and not so far off that it does not seem real, and hopefully the 1/5 sounds scary enough to convince people that it is worth considering as most people find long term risks confusing and hard to relate to in a personal sense. And this is just the effect on heart attacks, they prevent a lot of other problems, many just as nasty like strokes as well.

 

[HereKittyKitty]

So im a bit older and got on reta to jump start my weight loss with plans for a 3-6 month cycle before stopping use and just maintaining a lower daily calorie intake than I was eating before I got on the reta. I understand it's going to be hard, but I think it's doable. BUT I dont know what it's like after getting off reta. Is it a lot tougher than I am expecting? Food noise was never too bad....except for weekends. Weekends ruin me and the reta has really helped with that.

Also, are reta and the rest of these weight loss drugs meant to be used long term...or potentially even for life? I cant imagine the answer is yes to the permanent one...but im wondering if maybe 1-3 or even 5 years on is how doctors prescribe these drugs?

These are lifelong medications. Obesity is not a willpower issue. It is a metabolic and hormonal physiological condition.

 

[HereKittyKitty]

Its sad that asking for citations to read is taken negatively. Trust but verify isnt a bad thing and i didnt come in here to tell other people they dont know what theyre talking about, its the literal opposite. I came in here to reduce my learning curve.

And @domin8brix posted a slew of resources for you. So, enjoy them and learn from them. And thank them for providing such an exhaustive list of articles.