Alternating TSM10, IP10, and CP20 because they overlap in metabolic lanes. What are your thoughts on how to best optimize this stack? I'm not saying it is right, I'm saying I'm confused now, and would appreciate the wisdom and expertise of this community.
A.I. told me this was the optimal stack schedule, I'm skeptical
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lessthanhalf
GLP-1 Specialist
What AI are you using?
What are you trying to achieve with the peptides?
I use chatgpt in research scholar mode, plus extra prompts for improved scientific accuracy . And include "do not agree with me unless you can provide evidence". I guarantee it would not recommend that stack , it would say there is no human clinical trial evidence of safety or efficacy for those peptides, for general health or in any specific disease state. ( except tesamorelin for HIV lipodystrophy )
If you ask it the question for each of those peptides. " what is the evidence and quality of the evidence for use in humans of those peptides" you will get a much more complex answer and it is more likely to be scientifically accurate. Though they can still sometimes hallucinate.
AI's in general have a bad habit of agreeing with you, and can prefer a nice coherent story over actual accuracy of the information. An unprompted base model free AI can give pretty bad medical/health/pharmacology advice, or it can give excellent advice, but if it is not telling you basic science like not tested and safe in humans, then it is giving bad advice. It does not always mean peptides are a bad idea, but it is essential that you be given that basic information so you know these are not standard or recommended therapies, are experimental and there are risks, and it needs to tell you what those risks might be, not give you a nicely written out plan that strongly implies it is all perfectly harmless.
And if you decide to use those peptides in that stack or any other way you need to research them and know what they can do and what harms they could cause.
What are you trying to achieve with the peptides?
I use chatgpt in research scholar mode, plus extra prompts for improved scientific accuracy . And include "do not agree with me unless you can provide evidence". I guarantee it would not recommend that stack , it would say there is no human clinical trial evidence of safety or efficacy for those peptides, for general health or in any specific disease state. ( except tesamorelin for HIV lipodystrophy )
If you ask it the question for each of those peptides. " what is the evidence and quality of the evidence for use in humans of those peptides" you will get a much more complex answer and it is more likely to be scientifically accurate. Though they can still sometimes hallucinate.
AI's in general have a bad habit of agreeing with you, and can prefer a nice coherent story over actual accuracy of the information. An unprompted base model free AI can give pretty bad medical/health/pharmacology advice, or it can give excellent advice, but if it is not telling you basic science like not tested and safe in humans, then it is giving bad advice. It does not always mean peptides are a bad idea, but it is essential that you be given that basic information so you know these are not standard or recommended therapies, are experimental and there are risks, and it needs to tell you what those risks might be, not give you a nicely written out plan that strongly implies it is all perfectly harmless.
And if you decide to use those peptides in that stack or any other way you need to research them and know what they can do and what harms they could cause.
lessthanhalf
GLP-1 Specialist
For more specific answers would need to know age, height, start weight, target weight, current weight, lost over how long, any other drugs/peptides/health problems that are relevant etc, exercise level?
I appreciate your detailed response!lessthanhalf said:
Age 56
Height 6'5'
Weight :
Starting 301
Target 240
Current 277
Time it took to lose : ten weeks,
Peps : that's essentially my stack up there.
Exercise : Lift 5-6 days a week, walk/run/hike (treadmill) 3-4 days a week.
Eating real light, mosttly protein, in a solid caloric deficit.
Healthy as a horse, just a touch fat. Sleep like the dead.
Gt3294a
GLP-1 Enthusiast
AI was hallucinating.jason370 said:
Smiter
New member
Keep it simple. If you are at this stage already, even enjoying such an envious sleep state, stick to Reta and Tesa first thing in the morning fasted. After nearing your visceral fat goal, IF needed, IF no joint pain, water retention, or any other sides, you can choose the CJC for fun. Right now, you can try eating 30 grams of collagen, vitamin C, and hyaluronic acid daily. You may also do worse than looking at glutamine, glucosamine+chondroitin.jason370 said:
lessthanhalf
GLP-1 Specialist
That was quite hard to work out what the peptides were from just the abbreviations, I think I worked it out except W-V ( ?wolverine ?) I cannot find W-V on a standard vendor list.
I would agree that from what I have read of the research, AOD probably does not work, so probably not much point in it. Some of the research talked about it killing off fat cells, which is actually something you do not want, as it can worsen insulin resistance and could cause patchy fat cell loss, so it is either a possibly bad idea or it does not work.
DSIP, I have not read much on.
Again from what I have read KLOW has a bunch of very interesting sounding peptides in it, which do have effects, but most of them have not been tested in humans, and it has never been tested as a mixture even in animals. The idea of taking a untested peptide that alters the activity of several thousand different genes in various tissues, just sounds intrinsically risky. My basic logic on it is - if it did what people claim, which is to increase growth of connective tissue in ligaments and in the skin, it could also increase growth of connective tissue in vital organs like the liver or heart ( cirrhosis or heart failure ), which is really something you do not want. So if it works it is dangerous and if it doesn't then there is no point. I cannot see an obvious error in my logic. But trying to argue against KLOW or GLOW seems pointless, after reading hundreds or thousands of posts saying it fixed my bad shoulder or similar, it has been repeated so many times that people just believe it works, just because they have seen it said so many times, regardless of the underlying science.
The secretagogue/gh/ghrelin agonist combo , to me sounds more complicated than it needs to be, Ghrelin agonists can increase weight and appetite, which might be something people want on a bulking cycle, but not otherwise. The only definite disadvantage of using 3 drugs to do the same job instead of one is higher chance of side effects and allergic reactions. Assuming an average of 1 to 5% for a generalised skin rash type allergic response, it is not a completely irrelevant or trivial issue, but not super likely either. But if it was as high as 5% which is not at all uncommon then 3 x that is 15%, rather than 5%.
Any or all of those can cause adverse effects relating to GH or IGF-1, I think the doses are reasonable, but getting IGF-1, blood sugar and hb1ac checked as well as basic cardiovascular risk factors like lipids and bp are a good idea, even if you are not severely obese and obviously at high risk, you are getting to the age where getting that checked out is a good idea anyway. And look up and know what side effects are possible, just so you know and so you are not surprised if you start getting fluid retention or carpal tunnel syndrome.
I would imagine the combination of reta and exercise are doing 90-95% of the work in achieving what you are looking for.
I would agree that from what I have read of the research, AOD probably does not work, so probably not much point in it. Some of the research talked about it killing off fat cells, which is actually something you do not want, as it can worsen insulin resistance and could cause patchy fat cell loss, so it is either a possibly bad idea or it does not work.
DSIP, I have not read much on.
Again from what I have read KLOW has a bunch of very interesting sounding peptides in it, which do have effects, but most of them have not been tested in humans, and it has never been tested as a mixture even in animals. The idea of taking a untested peptide that alters the activity of several thousand different genes in various tissues, just sounds intrinsically risky. My basic logic on it is - if it did what people claim, which is to increase growth of connective tissue in ligaments and in the skin, it could also increase growth of connective tissue in vital organs like the liver or heart ( cirrhosis or heart failure ), which is really something you do not want. So if it works it is dangerous and if it doesn't then there is no point. I cannot see an obvious error in my logic. But trying to argue against KLOW or GLOW seems pointless, after reading hundreds or thousands of posts saying it fixed my bad shoulder or similar, it has been repeated so many times that people just believe it works, just because they have seen it said so many times, regardless of the underlying science.
The secretagogue/gh/ghrelin agonist combo , to me sounds more complicated than it needs to be, Ghrelin agonists can increase weight and appetite, which might be something people want on a bulking cycle, but not otherwise. The only definite disadvantage of using 3 drugs to do the same job instead of one is higher chance of side effects and allergic reactions. Assuming an average of 1 to 5% for a generalised skin rash type allergic response, it is not a completely irrelevant or trivial issue, but not super likely either. But if it was as high as 5% which is not at all uncommon then 3 x that is 15%, rather than 5%.
Any or all of those can cause adverse effects relating to GH or IGF-1, I think the doses are reasonable, but getting IGF-1, blood sugar and hb1ac checked as well as basic cardiovascular risk factors like lipids and bp are a good idea, even if you are not severely obese and obviously at high risk, you are getting to the age where getting that checked out is a good idea anyway. And look up and know what side effects are possible, just so you know and so you are not surprised if you start getting fluid retention or carpal tunnel syndrome.
I would imagine the combination of reta and exercise are doing 90-95% of the work in achieving what you are looking for.
Bigdog0628
GLP-1 Apprentice
They must be using ChatGLPt
Turbo-Farmer
GLP-1 Enthusiast
Disclaimer: I am an AI, not a doctor. If you are considering metabolic medication, please consult a medical professional to discuss your specific health needs.jason370 said:
This i what I got asking AI about peptides
wonttellyou
GLP-1 Apprentice
LLMs don't produce facts. They produce probabilities. Stop asking them anything medical.
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