有人有过这种反应吗?

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FlowerFairy said:
6.25 units tells us nothing. Mg. Use mg.
Normally I'm with you 100% when it comes to the whole units thing, but to be fair he did mention the specific dilution ratio in another thread.

But yeah, any time anyone refers to their dosage in units instead of mg/mL I want to reach through the screen and shake some sense into them.
 
Thsnk

ZippityDooDah said:
Normally I'm with you 100% when it comes to the whole units thing, but to be fair he did mention the specific dilution ratio in another thread.

But yeah, any time anyone refers to their dosage in units instead of mg/mL I want to reach through the screen and shake some sense into them.
Thank you so much. Sounds like to me it may be something to do with the dilution and the amount being injected. I’ll check out the link you posted for bac water and in my new vial I’ll try a new amount… ofcourse as always I’ll read and research before mixing and injecting my next vial 🙂 . What is your opinion on the needles to use ?
 
Sorry that we were not able to help you enough in the other thread that you felt that you needed to make another...
 
ZippityDooDah said:
It's fine, but jeez they really went out of their way to make something relatively simple seem unnecessarily convoluted.

It's also a good indicator that the owner of that shop isn't very bright. The history of the FDA going after peptide vendors is rife with examples of them targeting the low-hanging fruit of vendors openly discussing human use despite slapping the 'ol "research use only, not for human use" labels all over the place. 🤪

Agree, when starting this journey I literally needed things spoon feeded. Thanks to this and other forums I have been able to learn little by little.
 
feijao said:
Sorry that we were not able to help you enough in the other thread that you felt that you needed to make another...
I apologize I’m new and learning how all this works. I appreciate your help and advice 🙂 it is much appreciated !
 
ZippityDooDah said:
Normally I'm with you 100% when it comes to the whole units thing, but to be fair he did mention the specific dilution ratio in another thread.

But yeah, any time anyone refers to their dosage in units instead of mg/mL I want to reach through the screen and shake some sense into them.
Yeah. I saw that after I posted. And yes, it’s probably a good thing we can’t reach through the screen.
 
JAYB820 said:
Thsnk

Thank you so much. Sounds like to me it may be something to do with the dilution and the amount being injected. I’ll check out the link you posted for bac water and in my new vial I’ll try a new amount… ofcourse as always I’ll read and research before mixing and injecting my next vial 🙂 . What is your opinion on the needles to use ?
I’m no help there- I just used the insulin needles I had left from my diabetic cat. Then switched to a pen, so I’m even less help. Theoretically the finer the gauge the less pain, but other things come into play, like drawing up the dose then injecting- that rubber stopper can dull a needle quickly.
 
Higher concentrations have been shown pretty conclusively to increase the risk of side effects in a variety of other injections, so it's a possibility here.
 
FlowerFairy said:
我在这方面帮不上忙——我用的是我之前给患有糖尿病的猫咪注射胰岛素剩下的针头。后来我又换成了胰岛素笔,所以就更帮不上忙了。理论上来说,针头越细疼痛感越轻,但实际情况还不一样,比如抽取药液和注射的过程——那个橡胶塞会很快磨损针头。
橡胶塞很硬很厚。我常常在想,如果针头稍微长一点会不会有帮助。不管是什么原因,我都会弄清楚的。 🙂 我怀疑是抑菌水的问题,如果不是,我会在下一瓶里多加点抑菌水,如果还是不行,我就试试换个尺寸的针头。
 
JAYB820 said:
很高兴知道这一点,非常感谢!它真的非常有效,我不想因为轻微的反应就停用。通常3、4天后就会消失……

我的抑菌水是从Research Peptide订购的。我会查一下有没有其他人也有过类似的反应……

我听说Hospira牌子的不错。如果真是抑菌水的问题,下次配药前我会订购Hospira牌子的。

我可能会尝试只注射一点点抑菌水,看看是不是它引起的……如果不是,我会订购新的针头,并在下一瓶新药里多加一些抑菌水。非常感谢! 🙂
你也可以先吸取一定剂量的Tirz,然后再用注射器吸取一些抑菌水来稀释一下。这样你仍然能获得完整的Tirz剂量,同时又有额外的稀释液缓冲。
 
JAYB820 said:
希望这能帮到你!
抱歉,我不是在问纸上计算的问题,而是想问如何用注射器准确地抽取 6.25 单位?

我再确认一下,您说的是 0.0625 毫升/0.0625 立方厘米吗?

我用的是类似的(更细的)Easy Touch 31G 1cc(1ml)5/8英寸注射器,除非用放大镜,否则很难看出6个单位和7个单位的区别。如果剂量有偏差,可能会有15%的差别。如果你想把剂量控制在这个范围内,一个建议是使用0.3cc的注射器。

是的,如果你没有完全对准中心,有些塞子会感觉比较硬。有空的时候,可以取下一个塞子仔细观察一下。或者旋转药瓶,看看塞子上的开口!你必须对准那个开口。它们的设计各不相同。

就像FlowerFairy说的那样,如果你在注射前用2-3个塞子试过,你会感觉到“钝化”,这可能会导致轻微的注射不充分。为了稀释更多药液而吸入更多药液,会进一步使斜面变钝。我不会在腹部皮肤比较嫩的地方注射,我会选择腰部两侧的赘肉。皮肤质地更像皮革,脂肪更厚。

向 2 毫升的药瓶中加入 3 毫升的细菌培养液,会使抽取第一剂药物变得困难,因为空气间隙非常小,会形成真空。需要在抽取前先用注射器吸入空气,注入药瓶中,以产生较小的压力。
 
JAYB820 said:
谢谢!

非常感谢!听起来可能跟稀释度和注射量有关。我会看看你发的关于抑菌水的链接,然后在新的药瓶里试试新的剂量……当然,和往常一样,在配制和注射下一瓶药之前,我都会仔细阅读和研究。 🙂 您对使用哪种针头有什么看法?
我一直在用Easy Touch 30g 5/16英寸的针头。31号针头太细了,我都弯过几次了。就像 @AndyPanda 提到的,我打算用1/2英寸的针头来注射那些会刺痛的东西。不过GLP-1对我来说不刺痛。
 
StonePny said:
我一直在用Easy Touch 30g 5/16英寸的针头。31号针头太细了,我都弯过几次了。就像 @AndyPanda 提到的,我打算用1/2英寸的针头来注射那些会刺痛的东西。不过GLP-1对我来说不刺痛。
Thanks! I tested some bac water today and no reaction. My guess it has to do with the tirzepatide. Going to try injecting in my thigh next week with a little more bac water . Thinking 100 units for 45 mg is too much for me . Going to try 300 units of bac
 
ZippityDooDah said:
I've never had any real ISR's (injection site reactions). About the worst I've ever had was a little PIP (post-injection pain) and on a handful of occasions a little temporary itching.

Anything other than Hospira BAC (or some of the more reliable Chinese), including the mystery bathtub waters - especially from the Amazonian Empire - is always a risk IMHO, but if you used the name-brand stuff I would easily rule that out.

The high concentration may have played a part, or it could be something as simple as your body over-reacting to the needle puncture itself or a number of other little things. Compared to others I've seen it looks pretty mild so as long as it clears up I wouldn't worry about it too much.

One of the things I learned early on in this adventure was to invest in some 3ml syringes and needles (25 gauge) to use for reconstitution. It makes the process easier and faster since a larger bore needle moves a lot more fluid a lot faster than a 30 or 31 gauge insulin syringe, and it makes using more than 1ml of fluid to reconstitute a one-step process and probably a bit more accurate.
So this could be it as well… I been using a tanning bed before vacation next month. I bet the uv light is making the injections on my stomach react due to slightly burning etc. tried the bac water in my thigh no reaction today. Going to wait for the reaction to clear and then try future injections in thigh for bit .
 
I

StonePny said:
I've been using the Easy Touch 30g 5/16". The 31 gauge is so fine, I've bent the needle a couple of times. As @AndyPanda mentioned, I'm thinking of using 1/2" for the things that sting. But glp-1 doesn't sting for me.
also think it could be reacting from using a tanning bed… may be making my skin sensitive esp where I inject,.. may try thigh when this all clears up…
 
TooBigtoFail said:
Sorry, was not about the paper calculation, but how do you draw exactly 6.25u on a syringe?

Just to clarify, are saying .0625 ml / 0.0625cc?

I use similar (thinner) Easy Touch 31G 1cc(1ml) 5/8", and would be hard press to see the difference between 6 or 7u unless I use a magnifying glass. And if I am off, would mean a 15% difference in dosage. One suggestion if you want to stay within that dosage range is to use 0.3cc syringes.

Yes, some stoppers feel harder if you are not 100% in the center. When you have a moment, take a stopper out and study it. Or rotate the vial, and see the open slot in the stopper! You got to hit within that gap. They vary in design.

As FlowerFairy said, if you use it thru 2-3 stoppers before pinning, you will feel the 'dullness' which can cause a small isr. Pulling more bac into the syringe, to dilute more, can further dull the bevel. I do not pin in the belly, where the 'baby' skin is. I use the love handles, where the skin is more leather like and thicker fat.

Adding 3ml of bac to the 2ml vial, will make it harder to draw the first dose out because the air gap is very small. Creates a vacuum. Need to pull air in the syringe, inject it in the vial, before you draw, to create small pressure.
Thank you. The belly may be too sensitive. I may try my love handles or thigh. I also been tanning in a tanning bed for awhile before vacation. This also could have caused reactions since my skin was prob already sensitive /dry/burnt….. I injected some bac water into my thigh and no reaction so that’s a good sign!
 
m1tkam said:
Agree, when starting this journey I literally needed things spoon feeded. Thanks to this and other forums I have been able to learn little by little.
Thank you. The belly may be too sensitive. I may try my love handles or thigh. I also been tanning in a tanning bed for awhile before vacation. This also could have caused reactions since my skin was prob already sensitive /dry/burnt….. I injected some bac water into my thigh and no reaction so that’s a good sign!
 
TooBigtoFail said:
Sorry, was not about the paper calculation, but how do you draw exactly 6.25u on a syringe?

Just to clarify, are saying .0625 ml / 0.0625cc?

I use similar (thinner) Easy Touch 31G 1cc(1ml) 5/8", and would be hard press to see the difference between 6 or 7u unless I use a magnifying glass. And if I am off, would mean a 15% difference in dosage. One suggestion if you want to stay within that dosage range is to use 0.3cc syringes.

Yes, some stoppers feel harder if you are not 100% in the center. When you have a moment, take a stopper out and study it. Or rotate the vial, and see the open slot in the stopper! You got to hit within that gap. They vary in design.

As FlowerFairy said, if you use it thru 2-3 stoppers before pinning, you will feel the 'dullness' which can cause a small isr. Pulling more bac into the syringe, to dilute more, can further dull the bevel. I do not pin in the belly, where the 'baby' skin is. I use the love handles, where the skin is more leather like and thicker fat.

Adding 3ml of bac to the 2ml vial, will make it harder to draw the first dose out because the air gap is very small. Creates a vacuum. Need to pull air in the syringe, inject it in the vial, before you draw, to create small pressure.
Thank you. The belly may be too sensitive. I may try my love handles or thigh. I also been tanning in a tanning bed for awhile before vacation. This also could have caused reactions since my skin was prob already sensitive /dry/burnt….. I injected some bac water into my thigh and no reaction so that’s a good sign!
 
ZippityDooDah said:
One of the things I learned early on in this adventure was to invest in some 3ml syringes and needles (25 gauge) to use for reconstitution. It makes the process easier and faster since a larger bore needle moves a lot more fluid a lot faster than a 30 or 31 gauge insulin syringe, and it makes using more than 1ml of fluid to reconstitute a one-step process and probably a bit more accurate.
In addition to this great advice, pick up some 1.5" luer lock needles while you're shopping for the other stuff. The 1.5" needles will reach to the bottom of a standard 3ml vial so you don't have to play the upside-down-did-I-get-it-all game. These are especially helpful if you combine vials and/or fill pen cartridges. Just like Gonk does. He loves his pens.
 
I have had this reaction every single time since I started tirz last year. Have used 3 different suppliers and use either sterile water or bac water from medical supply. My friend is on name brand thru her doctor and also has the same reaction every time. According to her doc, some people just have an allergic or immune system reaction to the drugs and nothing you can do to avoid it. The only thing that I have found that helps for the itching is a cold compress. It usually heals within a few days.
 
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