我的Reta用药方案需要调整吗？求建议。

[tendency]

大家好，我是GLP-1受体激动剂的新手，之前没用过。大约六周前开始使用瑞他曲肽（Retatrutide），剂量逐渐增加到目前的方案，即每四天注射1毫克。所以，如果我周一注射，那么下一次注射就是周五。这个剂量和注射时间已经持续了三周。

但是，我注意到，在下次注射的前一天（例如上例中的周四），我的食欲和对食物的渴望开始增强。虽然没有特别严重，但我有点担心，而且这两天很难坚持节食。

我不想增加每周的瑞他曲肽剂量，因为目前的效果很好，我每周稳定减重1磅，但我正在考虑改为每三天注射一次，例如上例中的周一和周四各注射一次。我还打算将每次注射的剂量从1毫克减少到0.75毫克，以保持每周约2毫克的总剂量。

大家对此有什么想法或建议吗？食欲和“咕噜声”在第四天恢复正常吗？我以为Reta是每周注射一次，所以有点惊讶。或者，这是正常现象吗？其他人也有这种情况吗？谢谢！

 

[GeraltRedhammer]

Retatrutyd 抑制饥饿感的效果不如其他 GLP-1 类药物。服用期间感到饥饿是正常的。不过，我觉得它能让我们更好地控制是否屈服于饥饿而进食。

就我个人而言，Retatrutyd 一周内的效果不稳定让我感到困扰，所以我改为每 5 天服用一次。

 

[Kalinser]

Retatrutyd 抑制饥饿感的效果不如其他 GLP-1 类药物。服用期间感到饥饿是正常的。不过，我觉得它能让我们更好地控制是否屈服于饥饿而进食。

就我个人而言，Retatrutyd 一周内的效果不稳定让我感到困扰，所以我改为每 5 天服用一次。

你服用的剂量足够高吗？

 

[GeraltRedhammer]

Bioreę 2 mg co 5 dni。请注意，请注意以下事项。 4 razy w tygodniu i powoli tracę na wadze – średnio 0,8 kg tygodniowo。 Mam nadzieję，że nie tracę masy mięśniowej，ale że nadal trochę rośnie。

Chciałbym dodać do tego ćwiczenia有氧运动，ale ze względu na dużą ilość pracy i nauki nie mam na to siły。

Schudłam ze 115 公斤做 105 公斤。 Myślę，że mogłabym zwiększyć dawkę， ale nie chcę tego robić， póki chudnę。

 

[tendency]

Per our good friend google translate (polish to english):

"I'm taking 2 mg every 5 days. I haven't lost my appetite, but I feel full much faster. I'm strength training four times a week and slowly losing weight – an average of 0.8 kg per week. I hope I'm not losing muscle mass, but that I'm still gaining some.

I'd like to add cardio to this, but due to my heavy workload and study schedule, I don't have the energy.

I've lost from 115 kg to 105 kg. I think I could increase the dose, but I don't want to do that while I'm losing weight."

 

[PAPoots]

If you're losing weight, I wouldn't increase the dose.

 

[NoMoreFatPants]

I've noticed, however, that the day prior to my next pin (Thursday in the above example) my appetite and food 'noise' are starting to escalate. Nothing crazy but I'm a little bothered by it and having a hard time sticking to my diet on these days.

I'd rather not increase my weekly Reta dosage as it's working well for me and I'm steadily losing 1lb/week but am considering moving to an every-3rd-day pin, so, for example pinning on Monday and then Thursday in the above example. I'd also lower my injection from 1mg/shot to .75mg/shot to maintain my overall dosage of about 2mg/week.

Maybe look into cagrilintide? I was on tirz/Mounjaro for almost a year and maxed out dose. I lost the appetite decrease effect and have been stalled 30lbs from goal since April of this year. I switched to Reta and I am currently titrating up... I pin 3mg every 5 days. The appetite control is not the same as the beginning months on tirz... so I've tried cagrilintide. This has definitely changed how I feel when it comes to food control. Research it.