Where oh where has my mg gone?

[Smiter]

Incredibly based, Smiter. I think you and me would get along well. I eat the stems while I pack the bowl.

capitalism FTW...we OWN the vial

 

[deluge]

and being the despo I am, I licked it.

Made me laugh!

OP, read up on minimizing/recovering filter waste. An air purge gets some back. A flush can recover more. Pre-wetting the filter allows you to retain the most.

Downside is each one of those evolutions requires another needle (except for the air purge). But there are ways to mitigate that, too. For example, use a cheap diabetic syringe to pre-wet the filter. Buy LuerLok needles in bulk to get the cost down to $.06/ea. Things like that.

Another possibility; check your pen for accuracy. I had one (from Amazon) that was wildly inaccurate. Mostly under-dosed, but occasionally over-dosed, too.

Good video on pen testing:

View: https://www.youtube.com/watch?v=eJdzUaAEC4o

 

[dancs]

Unfortunately, filtering doesn’t remove endotoxins, so that second filtering is basically a waste of supplies and opens the possibility for further contamination. Endos are too small to be filtered. Some say that there is a special type of charged filter that might be able to remove endotoxins, is that what you’re using? If not, the second filtering is actually adding risk, not reducing it.

https://www.vwr.com/us/en/product/7605181/acrodisc-units-with-mustang-e-membrane-cytiva-formerly-pall-lab?r=1

I'm not entirely sure if this actually works or not, especially if I get the cheaper alternative from amazon (50 for $250), but it gives me peace of mind knowing it "may" help to a degree!

 

[cheesecake]

Interesting, in the product description they say that it filters out endotoxins. I would like to see some test results towards that claim. If true, it would be a game changer…

 

[FallingAlice]

I do not use a pen, but somehow lost 30u in my first reconstitution. I was reading about it last night and the best info I could find said it may be related to "dead space" in each draw. Otherwise i cant figure out how 30u disappeared.

 

[BNLFL]

I do not use a pen, but somehow lost 30u in my first reconstitution. I was reading about it last night and the best info I could find said it may be related to "dead space" in each draw. Otherwise i cant figure out how 30u disappeared.

Filter, could’ve mismeasured or spilt some. 3mg is quite a bit.

 

[WLBLD]

What you’ve described about losing 45 units in those 10mg/1mL vials is way beyond the typical “holdback” in a filter. Some possible alternative hypotheses:

The pen is administering the wrong # of units

User error on the # of units administered (less likely with the 10mg since the math is easy)

The syringe using to draw the bac is not calibrated correctly (not likely)

Of all these, the first seems the most plausible. What type of pen are you using and have you tested it?

Yes so strange I have no clue other than lost to the filter & then maybe purged a bit more. I don't know, ha ha. Ive been checking & have at least 2 of us check I'm on the right # + calculate again each time for the larger mg cart (the 10 is such an easy one, ha ha). I don't want to make any mistakes after reading some of these stories.

I did test the pen several times. Its a Mrs Goodlife, We have several of these. Was accurate when pushing slowly. I don't think Im getting more (would prob be getting better results if that was the case, ha ha).

 

[BNLFL]

You’ll get it next time.

 

[WLBLD]

Made me laugh!

OP, read up on minimizing/recovering filter waste. An air purge gets some back. A flush can recover more. Pre-wetting the filter allows you to retain the most.

Downside is each one of those evolutions requires another needle (except for the air purge). But there are ways to mitigate that, too. For example, use a cheap diabetic syringe to pre-wet the filter. Buy LuerLok needles in bulk to get the cost down to $.06/ea. Things like that.

Another possibility; check your pen for accuracy. I had one (from Amazon) that was wildly inaccurate. Mostly under-dosed, but occasionally over-dosed, too.

Good video on pen testing:

View: https://www.youtube.com/watch?v=eJdzUaAEC4o

Thank you I just heard about purging lately (after I reconed all what I have at the moment). I'm definitely going to next time. I usually do about 2-3 carts at a time (last time more since you can freeze the Tirz)

I did buy in bulk I have over 100 so I have a lot to spare

I did check it several times with different doses. If I was getting higher doses faster I would prob be down more, ha ha

Thank you!!

 

[WLBLD]

I do not use a pen, but somehow lost 30u in my first reconstitution. I was reading about it last night and the best info I could find said it may be related to "dead space" in each draw. Otherwise i cant figure out how 30u disappeared.

Crazy it even happens w vials & syringes

 

[FallingAlice]

Filter, could’ve mismeasured or spilt some. 3mg is quite a bit.

I thought filter at first as well, but im really thinking it might have been r/t the insulin syringes or sterile vials somehow. My best friend, husband, and I are splitting a kit, so we did the recon together. I had her double check measurements. We live pretty rural and she didnt want to travel with predrawn syringes, so I drew her units for her month's dosage, she double checked before I added to a new sterile vial. Shes missing 10u and I was missing 20. Going to try different syringes next go round to see if there is any difference.

 

[FallingAlice]

Crazy it even happens w vials & syringes

Thats what I thought too, because I know my measurements were all good, I was just a little baffled by this.

 

[WLBLD]

Thats what I thought too, because I know my measurements were all good, I was just a little baffled by this.

Its crazy. Maybe there is evaporation? Thats the only other thing I can think of

 

[BNLFL]

I thought filter at first as well, but im really thinking it might have been r/t the insulin syringes or sterile vials somehow. My best friend, husband, and I are splitting a kit, so we did the recon together. I had her double check measurements. We live pretty rural and she didnt want to travel with predrawn syringes, so I drew her units for her month's dosage, she double checked before I added to a new sterile vial. Shes missing 10u and I was missing 20. Going to try different syringes next go round to see if there is any difference.

I’m betting you were looking at the bottom of the plunger when reconstituting and not the tip.

 

[Dilbert4Life]

A flush can recover more. Pre-wetting the filter allows you to retain the most.

By prewetting the filter, do you mean like flush the filter with bac before filtering the reconstituted liquid?

 

[deluge]

By prewetting the filter, do you mean like flush the filter with bac before filtering the reconstituted liquid?

Yes, exactly. Instead of the dry filter absorbing your reconstituted peptide, it'll absorb water, and (in theory) more of the reconstituted peptide will pass thru.

I don't bother with it, or even flushing the filter any longer. I just air purge the filter when done. Diminishing returns and all.

I've never seen anyone do a video on how much can be recovered via air purge vs flushing, pre-wetting, etc; but I'd be curious about the result.

 

[FallingAlice]

I dont know either. I

I’m betting you were looking at the bottom of the plunger when reconstituting and not the tip.

I dont think thats it; Ive been a nurse for 20 years so I have a good handle on how to use everything. (Filters were only thing new for me). Plus I had my bff double check all measurements behind me. Reconstitution day comes this week though, so im going to adjust a couple of things see how it goes this go round!