What’s your current stack? 🥰

[Pinmebaby1moretime]

The mg dose in units but not mL is effectively useless and can potentially lead to dangerous errors.

Yes, they all say that, but most aren't stupid enough to offer a calculator on their website clearly intended for human use. Take a look at this: https://www.dea.gov/press-releases/...nts-charged-operating-websites-illegally-sell and pay special attention to where it says "In addition, the labeling on the drugs sold and delivered to customers falsely stated that the drugs were “research compounds” and/or “not for human consumption.” Contrary to these representations, Fields and Mahan knew and intended that the drugs they sold were for human use, and through emails and posts on the Pinned Aminos Facebook group, they provided customers with information on the health benefits of the drugs they sold and directions on dosage."

If a peptide vendor is not smart enough to avoid admitting that their sales are intended for human use by having a calculator on their website (or selling syringes & BAC water), then I wouldn't trust their product. Plus when outfits like this do get shut down, the feds now have their customer list.

I have seen so many people buying grey, slapping a label on each vial and reselling it from their kitchens. They posting on social media all the benefits of human consumption as well… they probably don’t know of this case. They are clearly following the same footsteps…

 

[pnwest]

The mg dose in units but not mL is effectively useless and can potentially lead to dangerous errors.

Yes, they all say that, but most aren't stupid enough to offer a calculator on their website clearly intended for human use. Take a look at this: https://www.dea.gov/press-releases/...nts-charged-operating-websites-illegally-sell and pay special attention to where it says "In addition, the labeling on the drugs sold and delivered to customers falsely stated that the drugs were “research compounds” and/or “not for human consumption.” Contrary to these representations, Fields and Mahan knew and intended that the drugs they sold were for human use, and through emails and posts on the Pinned Aminos Facebook group, they provided customers with information on the health benefits of the drugs they sold and directions on dosage."

If a peptide vendor is not smart enough to avoid admitting that their sales are intended for human use by having a calculator on their website (or selling syringes & BAC water), then I wouldn't trust their product. Plus when outfits like this do get shut down, the feds now have their customer list.

Do you have a calculator you can suggest?

 

[m1tkam]

Do you have a calculator you can suggest?

Tirzepatide Dose Calculator | Fat Scientist, a community-supported resource for GLP-1 medication users

Simple calculator, trusted by hundreds of thousands of Reddit users, to help you figure out how many units of tirzepatide (Mounjaro/Zepbound) you need to take based on your desired dosage and the concentration of the medication in your vial.

www.fatscientist.com

 

[Lifeworthliving]

How long have you been taking Reta?

In my experience with switching from tirz to Reta, that first month (and a half) are all on faith. Eventually it will kick in and you will notice the appetite suppression and early satiety again. But you have to be patient!

I was on 12.5mg of Tirz for a long while, lost 80lbs, had hell of a plateau, switched over to Reta, and have been at 2mg for four weeks. Switching over, what dose schedule did you do? Debating whether to increase to 4mg, I haven't seen any changes on Reta yet. I have more hunger, and I have been focusing on protein and weights; however, the scale hasn't gone down or up.

 

[kanuck]

I was on 12.5mg of Tirz for a long while, lost 80lbs, had hell of a plateau, switched over to Reta, and have been at 2mg for four weeks. Switching over, what dose schedule did you do? Debating whether to increase to 4mg, I haven't seen any changes on Reta yet. I have more hunger, and I have been focusing on protein and weights; however, the scale hasn't gone down or up.

Am in similar situation. Plateau'ing on Tirz 11mg, have reta coming in and trying to figure out a good starting point for the switch over. 2mg seems like the safe default so will likely start there

 

[Calm Logic]

The highest starting dose in a study I have seen was 4 mg of reta:

Triple-Hormone-Receptor Agonist Retatrutide for Obesity - A Phase 2 Trial - PubMed

In adults with obesity, retatrutide treatment for 48 weeks resulted in substantial reductions in body weight. (Funded by Eli Lilly; ClinicalTrials.gov number, NCT04881760.).

pubmed.ncbi.nlm.nih.gov

Obviously, side effects were higher compared to the 2 mg group in the same study:

The most common adverse events in the retatrutide groups were gastrointestinal; these events were dose-related, were mostly mild to moderate in severity, and were partially mitigated with a lower starting dose (2 mg vs. 4 mg). Dose-dependent increases in heart rate peaked at 24 weeks and declined thereafter.

 

[RocketGotRobbed]

My stack is optimized based upoon my blood tests which I do every 6 months. I am a testicular cancer survivor and as such there are some things that get out of whack such has high FSH as the remaining testicle overcompensates. Normal optimization would say to add Kisspeptin but with only 1 testicle, the Kisspeptin is overkill and not needed. It is just another reason you should really get full panel tests at least annually and another reason that the healthcare system is jacked (because they won't pay for full panels). This last go round, my DHEA was through the floor for no known reason so I have added that in orally.

 

[ctlove]

Reta 1-1.5 mg once a week for maintenance.

Klow dosed off 2 mg GHK-cu daily for pain/inflammation.

NAD+ 65 mg 3 times a week for energy.

GH 2 IU at night

TA 1 800 mcg 3 x week as needed when feeling under the weather or around sick people to prevent getting sick.

I have melanotan 1 in the freezer that I might start using soon for sun protection.

I'm reading conflicting articles on KLOW and GH stacking being a no go. You still running this? Have you checked your IGF-1 blood work? I want to run this, but protocols are telling me otherwise.

 

[Loves2eat]

I'm reading conflicting articles on KLOW and GH stacking being a no go. You still running this? Have you checked your IGF-1 blood work? I want to run this, but protocols are telling me otherwise.

I haven’t heard that, but I’m not on Klow right now. I’m still on GH though. IGF-1 was tested in July while on both Klow and GH and had increased from 57 in March up to 190.

 

[ctlove]

I haven’t heard that, but I’m not on Klow right now. I’m still on GH though. IGF-1 was tested in July while on both Klow and GH and had increased from 57 in March up to 190.

Here is one of the reference protocols. Under the interactions section it called out avoiding the combination. https://pep-pedia.org/peptides/klow

i already bought the KLOW, think I'll run it and keep an eye of IGF-1 levels. Thanks for the response.

 

[RocketGotRobbed]

Here is one of the reference protocols. Under the interactions section it called out avoiding the combination. https://pep-pedia.org/peptides/klow

i already bought the KLOW, think I'll run it and keep an eye of IGF-1 levels. Thanks for the response.

There is no reason to not run them together. The issue that some see is completely theoretical with no data to back it up. Ultimately, KLOW already includes BPC-157, TB-500, KPV, and GHK-Cu. These accelerate healing, modulate inflammation, and stimulate tissue growth. HGH is also anabolic (somewhat) and regenerative. In theory, combining them could “oversaturate” certain pathways (fibroblast activity (I think was listed), angiogenesis, extracellular matrix turnover). Some docs worry this may blunt efficacy or create unpredictable tissue remodeling like scarring. Most of this advice is anecdotal. It’s more “precautionary principle” than proven toxicity. My former clinic ran them together and that's headed by an oncology doctor. As a side note, I would be careful with pep-pedia. I am not sure anyone is checking the infoo their AI spits ut. We have found soome great info and some downright wrong info on there. Happy pinning!