Weight Loss Drugs Show Increasing Benefit in Skin Disease

[Karma-Electron]

Weight-Loss Drugs Show Increasing Benefit in Skin Disease

Improvements with GLP-1 RAs in psoriasis and other chronic skin diseases point to their increased use in dermatology and a potential role for dermatologists in obesity management.

www.medscape.com

Thinner and more beautiful? Hard to beat that.

I'm 70 and got a quarter-sized patch of psoriasis on one ankle last year. Dermatologist couldn't care less. But in the 3 months since I started tirzepatide, the patch is smaller and no long itchy.

 

[Iamnew2this]

This med is nothing short from amazing

 

[Oxcolette]

I have it on my scalp. It’s helped tremendously!

 

[zanny-kanny]

Tirz has anti-inflammatory action. Probably all GLP1s have it, but there are currently no studies showing this. Probably will be in the future, if not already in the works.

Reta is definitely anti-inflammatory. I know because I used Reta exclusively from June 2024 to April 2025, had 3 blood draws during that time, and watched my inflammation level decrease on each draw.

 

[feijao]

Tirz has anti-inflammatory action. Probably all GLP1s have it, but there are currently no studies showing this. Probably will be in the future, if not already in the works.

Reta is definitely anti-inflammatory. I know because I used Reta exclusively from June 2024 to April 2025, had 3 blood draws during that time, and watched my inflammation level decrease on each draw.

Happy to hear this! If the weight loss can take some pain off the joints and reduce inflammation via some other mechanism that's an A plus plus for me!

 

[Skidude]

Tirz has anti-inflammatory action. Probably all GLP1s have it, but there are currently no studies showing this. Probably will be in the future, if not already in the works.

Reta is definitely anti-inflammatory. I know because I used Reta exclusively from June 2024 to April 2025, had 3 blood draws during that time, and watched my inflammation level decrease on each draw.

These drugs are nothing short of miraculous and the data that is being gathered show so many benefits they provide outside of weight loss.

Here are just a few articles that might be fun to read:

Glucagon-like peptide-1: a multi-faceted anti-inflammatory agent - PMC

Inflammation contributes to many chronic conditions. It is often associated with circulating pro-inflammatory cytokines and immune cells. GLP-1 levels correlate with disease severity. They are often elevated and can serve as markers of inflammation. ...

pmc.ncbi.nlm.nih.gov

https://www.sciencedirect.com/science/article/abs/pii/S1043661822002651#:~:text=Many%20studies%20showed%20as%20GLP,monocytes/macrophages%20%5B24%5D.

GLP-1 Drugs: Ozempic, Mounjaro, Zepbound: A Promising Treatment for Autoimmune Diseases? - Rheumatologist OnCall

Explore the potential of GLP-1 drugs like Ozempic, Mounjaro, and Zepbound in treating autoimmune diseases. Discover their benefits beyond weight loss!

rheumatologistoncall.com

Anti-Inflammatory Effects of GLP-1-Based Therapies beyond Glucose Control - PMC

Glucagon-like peptide-1 (GLP-1) is an incretin hormone mainly secreted from intestinal L cells in response to nutrient ingestion. GLP-1 has beneficial effects for glucose homeostasis by stimulating insulin secretion from pancreatic beta-cells, ...

pmc.ncbi.nlm.nih.gov

 

[Iamnew2this]

They definitely are life-changing! Great articles

 

[Skidude]

They definitely are life-changing! Great articles

I really liked the first one-

100+ years in the process of understanding GLPs

and this- ( I had added some definitions in red)

 

[Morbius]

Every time I seen an article like this I want to add a year to my stockpile.

 

[Skidude]

Every time I seen an article like this I want to add a year to my stockpile.

Having had a nephrectomy and, as a result, being concerned about all things kidney related; this one is very interesting as well.

Results: RIRI resulted in a significant elevation in serum urea, serum creatinine and renal levels of KIM-1, IL-6, caspase-3, Akt, and LC3-B while aconcurrently reduction in renal GSH level. Tirzepatide treatment diminished the severity of kidney damage by alleviating inflammatory apoptoticand autophagy markers, augmenting antioxidant activity and improving histopathological consequences.