Tirzepitide and Omeprazole-bad acid reflux

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Peevee said:
Dude my doc told me taking omeprazole long term is a bad idea
I've got permanently banned off the peptide subreddit by challenging the mods lol
 
For some people, it reduces nutritional absorption significantly. I was on it for 7 years before realizing I am one of those people. (My eGFR raised to >140 after stopping to take it too)

geoguy78 said:
I've been on it for decades. Just need to check your magnesium

I tried using it for GLP1 acid reflux and it wasn't working too well. Then I started using generic pepcid ac and it's been magical in comparison:

https://www.amazon.com/dp/B0CLF1QNYP <-- super cheap in comparison
 
Hi there, I had a similar reaction when I started taking Tirz 1.5yrs ago. I had been on omeprazole since my gall bladder removal surgery in 2009. Omeprazole wasn't taking care of my GERD any more so I did some research and people suggested esomeprazole (Generic Nexium). Took care of it right away. I switched to esomeprazole and haven't had any problems since!
 
Glp1judd said:
emerging science continues to show gut health is a result of “bad” bacteria and yeast outcompeting “good” bacteria.
I’ve seen this recommendation in multiple forums. I’m definitely going to pursue it.
 
Dee X said:
For some people, it reduces nutritional absorption significantly. I was on it for 7 years before realizing I am one of those people. (My eGFR raised to >140 after stopping to take it too)

I tried using it for GLP1 acid reflux and it wasn't working too well. Then I started using generic pepcid ac and it's been magical in comparison:

https://www.amazon.com/dp/B0CLF1QNYP
 
ksharpe said:
Hi there, I had a similar reaction when I started taking Tirz 1.5yrs ago. I had been on omeprazole since my gall bladder removal surgery in 2009. Omeprazole wasn't taking care of my GERD any more so I did some research and people suggested esomeprazole (Generic Nexium). Took care of it right away. I switched to esomeprazole and haven't had any problems since!
Is your gerd related to the gallbladder removal you think? I had mine out as well and have gerd. The other night some acid made it through my sinuses and out my nose. It was unpleasant.

My PCP say Pepcid was safe daily but very specifically said Pepcid not some of the proton pump inhibitors

Last time I lost some weight the issue went away so I just need to get there again
 
Peevee said:
Is your gerd related to the gallbladder removal you think? I had mine out as well and have gerd. The other night some acid made it through my sinuses and out my nose. It was unpleasant.

My PCP say Pepcid was safe daily but very specifically said Pepcid not some of the proton pump inhibitors

Last time I lost some weight the issue went away so I just need to get there again
Yes, my GERD was 100% related to my gallbladder removal. Clinically, it makes since since there isn't a place in your body to hold the "gall" so it continually "dumps" into your system. I changed my eating habits (no acidic, greasy foods) post gall bladder surgery and that helped also.

When I started on Tirz the GERD came back with a vengeance and I did enough research to see that Nexium was worth a try. It works, most of the time, for me. In the old days they used to tell people to put the head (headboard) of their beds up on cinder blocks so you sleep at a slight incline. Good ole fashion advice that works and is relative inexpensive.

Pepcid is safe as an H2 antagonist. Its worth a try. In the ER they shoot that in the bags if someone is in anaphylaxis. (you need both and H1 and H2 antagonist). The deal with any of those meds.. proton pump inhibitor or H2 antagonist is that they stop the acid production from happening. Once its already in your system.... tums etc is the only way to neutralize it.

Good luck! That acid into your sinus cavities sounds awful. Bland foods are the way to go and wait a couple of hours before you lay down. Its no fun but better than all that acid!
 
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