Those who stack Reta and Tirz—do you pin same time or alternate?

Status
Not open for further replies.
Beardboost said:
This is not for everyone, you have to experiment, take note of when the food noise and hunger starts coming back with each dosage, everyone reacts different, so far every 6 days for each peptide has been working best for me with no side effects, so make sure you start on a milligram level that suits your own body, ill place my plan to give you an idea, but shouldn't be copied and only used for research, takes time to dial in your own needs to gather information on how each peptide effects you personally.

I like to plan everything to keep on top of dosages and weight in one place without using apps, so I use Outlook calendar, I get a nice reminder the day before and on the day.

View attachment 20323
That is a smart idea, I might try doing this in addition to the Shotsy app. I do track sides but need to start paying attention to the noise.
 
Personally, I pin both on Friday mornings. 2mg Tirz, and 1.5mg Reta. I've been thinking about staggering my doses to have the peaks of each alternate, but the way I've been doing it feels fine and has been helping me not overeat on the weekends. That's what feels good for me, though. I'm sure each person is different.
 
Just wanted to say thanks, all. I've been on 15mg tirz for about a year. Just pinned my first 2mg Reta yesterday. And am going to stick with tirz at half or 1/3 my normal dose (so 7.5 or 5) and think I'll follow the advice here and stagger days.

I've seen posters here like me who were on high-dose tirz for a long time say they went straight into reta at much higher doses and dropping tirz altogether, but I want to keep some tirz for food noise.

This is maybe an unuseful post, but I just wanted to say thanks for all of you asking and answering the questions I had. Appreciate it!
 
I pin separately, every 4 days, staggering 2 days, that way it keeps a smoother experience.

T day1, R day 3, T day5, etc so I pine every other day.
 
domin8brix said:
I reconstituted my Reta finally today and plan to start it this weekend. Tomorrow would be my next Tirz pin (I split dose) and was wondering if I should pin my usual Tirz dose and the tiny Reta dose I plan to start with (.5) at the same time or do Reta tomorrow and Tirz on Sunday/Monday?
I havent heard of dosing tirz and reta alternating...whats the advantage to doing this?
 
coach chickpea said:
I havent heard of dosing tirz and reta alternating...whats the advantage to doing this?
I'm thinking of doing it. Well, split dosing eliminates the likelihood of food noise creeping in on the last few days of the week before the next dose. Also, tirz is supposed to have a stronger hunger suppressing effect than reta. This way you could keep the dose of both compounds low enough and maximize weight loss.
 
I've been doing Tirz every 5 days, I just dropped down from 7.5mg to 5mg, due to ISRs at 7.5mg. My Reta just came in this week so I took my first dose (2mg) on the same day as my Tirz. I'm feeling fine, so I think I'll keep taking both on the same day, every 5 days.
 
desinr-gal said:
I pin separately, every 4 days, staggering 2 days, that way it keeps a smoother experience.

T day1, R day 3, T day5, etc so I pine every other day.
Do you mind sharing how much you pin of each? Did you start at smaller doses and titrate up? And sides?
 
I've been on GLP1s for over three years. 2+ years on sema at the top (wegovy) dose before switching to tirz and pinning 15mg a week for about a year (through pcp). And I've always done a little cleansing routine to keep the slow gut moving-- I do a mix of psyllium and Super Colon Cleanse and chug.

I took my very first Reta dose (2mg) a few days ago at the same time when I would have normally taken my tirz, but chose to do Reta only (and no tirz) to ease into the Reta. I took my psyllium/SCC drink last night and HOLY CRAP did I suffer. I am NOT new to GLP1s, but the stomach ache I endured for about 12 hours was nothing short of epic. Not in the good way. And I feel confident this symptom is DEFINITELY a Reta thing because this didn't happen on tirz or sema. Ever. And I was a good 11 days past my most recent tirz dose (so it was definitely the Reta). Apropos of nothing I guess. All was fine eventually, but the road to fine was fraught and painful. Which... makes me thing the Reta is REALLY working. But man oh man, word to the wise if anyone out there has a pronounced experience with that kind of blocakge. If you're like me and do some things to keep the tummies moving and clear, there may be a serious cost of admission. Take caution and go slow with the fiber stuff.
 
I do a full Tirz dose at once but I split up my Reta into two weekly

So Thursday I do Tirz 7.5

Saturday 1.5mg reta

Tuesday 1.5mg reta

I get elevated heart rate that I HATE with Reta so that’s why I split it but it’s better imo to not take both Tirz and Reta the same day
 
timj382 said:
Do you mind sharing how much you pin of each? Did you start at smaller doses and titrate up? And sides?
Sure: I was micro dosing when I started. I was pinning Every other day; Tirz .7 and added .25 reta each pin. so effectively pinning everyday just alternating peps. Eventually I went to every 3 days each, staggered. and then I settled at every 4 days, so every other day I pin and it alternates.

The highest was 1.2 Reta, and 1.2 Tirz. That equals 2.325mg per week of each.

4.65mg per week total. I lost 52 lbs over a year. But the loss improved greatly after adding Reta.

I am down to .9 and 1.1 now trying to find a maintenance sweet spot.

Why pin so often?? For the same reason I drink coffee every morning, and not all of it on Mondays.. imagine the effects 14 coffees would have on the same day.

I arrived at this system after checking the dose and schedule on the GLP Plotter.

https://www.google.com/url?sa=t&source=web&rct=j&opi=89978449&url=https://glp1plotter.com/&ved=2ahUKEwjv3NvPvO6UAxVeKUQIHWjQMp4QFnoECB8QAQ&usg=AOvVaw1uWTntg7EbHktpBy7qxZ_x

It is very helpful to see the peak/valleys and how they interact.
 
A friend takes 13mg tirz and 3mg Reta, same day, because I give it to her, since her family is sketchy about her taking it. She has had zero side effects since starting on glp1s though.

We actually talked about splitting them, thinking it would help with hunger better, but she’s really been great doing it the same day. Down 60 pounds in 7 months, and no loose skin so far. 300–>240.
 
coach chickpea said:
I havent heard of dosing tirz and reta alternating...whats the advantage to doing this?
Basically getting the added food noise benefits of Tirz, and the overall benefits of both GLPs from Reta
 
jordekorn said:
A friend takes 13mg tirz and 3mg Reta, same day, because I give it to her, since her family is sketchy about her taking it. She has had zero side effects since starting on glp1s though.

We actually talked about splitting them, thinking it would help with hunger better, but she’s really been great doing it the same day. Down 60 pounds in 7 months, and no loose skin so far. 300–>240.
Wow. That's pretty high tirz with the reta, no? I mean, I was on 15mg weekly for a long time. But wanted to be cautious so cut mine down to 7.5mg when I added 2mg Reta last week alongside the tirz for the first time. A little over a week now. So far so good. Thanks for sharing you and your friend's experience.
 
timj382 said:
Wow. That's pretty high tirz with the reta, no? I mean, I was on 15mg weekly for a long time. But wanted to be cautious so cut mine down to 7.5mg when I added 2mg Reta last week alongside the tirz for the first time. A little over a week now. So far so good. Thanks for sharing you and your friend's experience.
It’s a little aggressive, but no sides and it’s kept her ibs in check. She is still losing weight and says she feels healthier, her hr is better weighing less even on Reta.

I don’t know where she goes from there when she plateaus. Hoping to hear more about stacking, I know Reta doesn’t work for me, too much hr increase. I think it severely dehydrates me, no matter what or how much I drink.
 
Status
Not open for further replies.

Members online

No members online now.

Forum statistics

Threads
4,434
Messages
86,405
Members
7,877
Latest member
jhonpdr
Back
Top