Calm Logic
GLP-1 Specialist
That's how I feel (keyword feel) about gluta IM injections vs oral NAC. I have a lot of "rust" to work on for now, and I can do both. And high does of NAC can raise hematocrit, in a bad way.
SS-31 + MOTs-C vs NAD+
- Thread starter Desieldogg
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trojanpeptide
GLP-1 Enthusiast
ok, I was just pointing out what i knew about the science. I'm glad it's working for you.tendency said:
tendency
GLP-1 Enthusiast
Here's my protocol logic:Twowheelr2 said:
David Sincother recommends 1000mg/day of NMN. I am assuming an NMN -> NAD conversion rate of 10%. This gets me to 100mg of NAD+ daily. I would posit most people (well, certainly if over 45 or so..) could run 50-100mg of NAD+ (SubQ or IM) daily, indefinitely.
I think this completely un-scientific and likely erroneous-in-a-number-of-assumptions protocol is about as good as the rat study, IMO
Anyhow, I've been taking 75mg NAD+ (buffered) daily via IM injection for the past 20 days and have been very pleased with the results. SubQ injections did next to nothing for me, for some reason.
Time will tell..
HereKittyKitty
GLP-1 Enthusiast
Where does this protocol originate?Loeve said:
CNCCurrency
GLP-1 Specialist
HereKittyKitty
GLP-1 Enthusiast
Well, that takes care of a lot of pressure to conform. 
I can't find the origin of it. There are a few protocols that are very similar. I just did an AI search and one of my own posts here was used as a citation.MeedzMoar said:
It's GIGO. I first saw it mid-2025 but that doesn't mean anything.PAPoots
GLP-1 Enthusiast
I started with that protocol and until the point where I was taking the MOTS-C and NAD and then I got hit with the energy of a pre-workout without any side effects. So I have my daytime energy sort of worked out, now I need to figure out sleep.i think if I could dial that in, my days would improve.
I know you've tried just about everything, but did you try NA Selank yet? I've been taking 600-800mcg SQ the first two nights after my Reta pin and It's been working great. You have my empathy.PAPoots said:
I just finished the protocol and I summarized the results:
Mitochondria Repair
I read here it’s spicy. I picked up buffered from Nexaph and … yes it’s spicy. My first pin I was like “whoah, so that’s what they mean!” I’ve been going 20mg 3x per week. Picked it up to try to decreasing adhedonia I have with tirz. It does help with energy, and my arguably poor sense of...
glp1forum.com
Mitochondria Repair
I read here it’s spicy. I picked up buffered from Nexaph and … yes it’s spicy. My first pin I was like “whoah, so that’s what they mean!” I’ve been going 20mg 3x per week. Picked it up to try to decreasing adhedonia I have with tirz. It does help with energy, and my arguably poor sense of...
glp1forum.com
lavender
GLP-1 Novice 🚫No Source Discussion🚫
Has anyone just kept on with a regular schedule of Mots-c or ss31 after this? Have seen some people saying this is good for mitochondrial repair but one of the points of that is to set you up so you can actually make the most of these two during longer term/regular use.
Curlygirlie
Recently Joined 🚫No Source Discussion🚫
I deal with the same. I have been on KLOW and that gave me a bump in my energy. I have been taking NAD+ and it helps even though its temporary-I take it daily at this point. I started SS31 5 days ago and it has made me more fatigued (which I’m hoping improves-I may lower my dose). I have not tried mots-c yet and I am waiting for slu-pp-32 capsules from Amazon, hoping they help.Desieldogg said:
PAPoots
GLP-1 Enthusiast
Are we talking about slu-pp-32 or slu-pp-332?
Madkate
GLP-1 Apprentice
How are you pinning it like a glp (sub q)Twowheelr2 said:
Twowheelr2
GLP-1 Enthusiast
Pretty much the same. MOTSc areas needed to be alternated due it ISRs. I mainly used glute area for MOTSc and 1/2 pin. The ISRs weren’t too bad for me. Small welts and some itchiness. And yes..SubQ.Madkate said:
Turbo-Farmer
GLP-1 Enthusiast
Started this one today, at least the 4mg of Ss-31,
I have been getting the nad+ from a tele-health because they take my HSA card.
I recently went to the Dr for a follow up on my a1c and it was in the pre T2D range slightly 5.8 with a fasting glucose of 94. However the alarming result was my fasting insulin was at 19.9 which puts my HOMA-IR (Homeostatic Model Assessment of Insulin Resistance) score at 4.6.
I am very hopeful that this protocol will allow me to improve that score and make the over fitness journey more sustainable.
My Dr is one of my biggest fans and she loves it that I go running every morning just to spite her and stay off the statins, blood pressure medication, etc.
We I first me her she told me my A1C was so high that there was no chance I could reverse the T2D.
I have been getting the nad+ from a tele-health because they take my HSA card.
I recently went to the Dr for a follow up on my a1c and it was in the pre T2D range slightly 5.8 with a fasting glucose of 94. However the alarming result was my fasting insulin was at 19.9 which puts my HOMA-IR (Homeostatic Model Assessment of Insulin Resistance) score at 4.6.
I am very hopeful that this protocol will allow me to improve that score and make the over fitness journey more sustainable.
My Dr is one of my biggest fans and she loves it that I go running every morning just to spite her and stay off the statins, blood pressure medication, etc.
We I first me her she told me my A1C was so high that there was no chance I could reverse the T2D.
SakeSan
GLP-1 Novice 🚫No Source Discussion🚫
Time for an updateSakeSan said:4 week update on running SS31 with some background:
Late 30s, I’ve been on low dose Reta (0.5mg e5d) for 4 months. No other peps or meds, except a cycle of glow50. Dropped 9% body fat, now around 19%. Took nad+ e3d 50mg and felt significant change in baseline energy. Finished a cycle of ss-31 4mg every day for last 25 days and I’m left with more energy than I can spend. I don’t remember the last time I went to bed without being tired, but still being able to sleep. My head is buzzing in the morning when I wake up. Sleep score is averaging 88 despite getting up at least once to pee at night. I’m going to start mots-c before workouts next week but honestly don’t even feel the need for it. I can stack 2 workouts in a day and not get tired. Recovery is better too. Didn’t even know I could raise my baseline energy levels this high.
Happy to answer any questions and help other level up
Pushed my physical limits with this stack. Got what I wanted but paid the price.
dropped bf% to 16%
overtraining kills libido
dropped ferritin due to overtraining and recovering from a surgery-
stopped nad, Reta completely
started pinealon and epitalon cycle for sleep optimization
oura ring could quantify my overtraining by looking at elevated rhr, dropped hrv. Fatigue was masked by nad+ but stress levels by oura ring showed significant time spent in stress everyday
it’s been a month since. Feeling much better. Libido is coming back. Got to get hormone panels and ferritin checked again before resuming nad+.
oura is showing 20% decline in rhr, more time spent in deep/rem, hrv is trending up. Signal to the body that famine is over. Time to spread my seed
HereKittyKitty
GLP-1 Enthusiast
Right, on!!!Turbo-Farmer said:
Lovedog100
GLP-1 Apprentice
You can make your own Nad+ cheap. Go and buy Niacin and Niacinamide tablets at your local health food store. Start with 100mg Niacin which is better than Niacinamide which you should get at least a 500mg tablet of. The Niacin will cause a temporary skin flush, it's the capillaries in your skin opening up. That happens in your brain as well, not to mention your dick if you have lost some libido. Take them daily. After a while, the flushing becomes less, and for a shorter time. Once you stop flushing, add another 100mg of Niacin to your protocol. Keep raising the amount of Niacin until you get to 500mg, that would give you a gram a day between the two. you could start replacing the amount of Niacinamide with the Niacin if you want, or keep taking 500mg of each. Your body will convert them to NAD. It's easier than injections, and a lot cheaper. I like to take 100mg of vitamin C with them, I've been told that it helps with the absorption.
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