Selank / Semax questions

[walkingdreadd]

I am looking to start some research on Selank and Semax. I have searched on here and a few other places and see a lot of conflicting answers to my questions and was hoping someone with experience in the research may be able to answer a few questions.

RS plans to do a 300mcg dose of each peptide in a 5/2 on/off schedule. In my research it seems this is best done in the morning. For my questions:

Can these be combined in the same shot without issue?

If doing 5/2 schedule do you need to be on 4 weeks off 4 weeks? I saw post say 2 weeks some say 4 etc.

What was your RS experience in the 4 weeks off? Did symptoms return fully?

RS's symptoms seem to prone to irritability and short temper that they think could be linked to depression but never really had any issues with "sadness".

Thank you for you time.

 

[DustAndDignity]

I am looking to start some research on Selank and Semax. I have searched on here and a few other places and see a lot of conflicting answers to my questions and was hoping someone with experience in the research may be able to answer a few questions.

RS plans to do a 300mcg dose of each peptide in a 5/2 on/off schedule. In my research it seems this is best done in the morning. For my questions:

Can these be combined in the same shot without issue?

If doing 5/2 schedule do you need to be on 4 weeks off 4 weeks? I saw post say 2 weeks some say 4 etc.

What was your RS experience in the 4 weeks off? Did symptoms return fully?

RS's symptoms seem to prone to irritability and short temper that they think could be linked to depression but never really had any issues with "sadness".

Thank you for you time.

Hey @walkingdreadd ,

Have you considered researching these intranasally (IN)? I’ve research both of these previously in that manner (250-600mcg) and experienced positive results from them.

I’ve debated re adding them back to my stack sub-q. I was planning on pinning them separately. Daily for a couple of weeks in the same manner in ran them IN, AM-Semax, Late Afternoon/PM- Selank.

It’s hard for me to pinpoint when symptoms returns as I didn’t go into my research seeking to solve for symptoms. My mindset was on enhancing my productivity and mood overall.

I also started using a dry sauna 4 times a week and Sensory Deprivation tanks 3 times a week where it’s just me, myself and I alone with my thoughts, my breath practicing mindfulness meditation. So I can’t definitively state what’s led me to the headspace that I’m in now. I’d say it’s a combo of all 3.

I’m following this thread to hear others feedback. Thanks for starting it back up. Best of luck!

 

[walkingdreadd]

Hey @walkingdreadd ,

Have you considered researching these intranasally (IN)? I’ve research both of these previously in that manner (250-600mcg) and experienced positive results from them.

I’ve debated re adding them back to my stack sub-q. I was planning on pinning them separately. Daily for a couple of weeks in the same manner in ran them IN, AM-Semax, Late Afternoon/PM- Selank.

It’s hard for me to pinpoint when symptoms returns as I didn’t go into my research seeking to solve for symptoms. My mindset was on enhancing my productivity and mood overall.

I also started using a dry sauna 4 times a week and Sensory Deprivation tanks 3 times a week where it’s just me, myself and I alone with my thoughts, my breath practicing mindfulness meditation. So I can’t definitively state what’s led me to the headspace that I’m in now. I’d say it’s a combo of all 3.

I’m following this thread to hear others feedback. Thanks for starting it back up. Best of luck!

Thank you very much for your input. I have read a bit about having RS use it as a nasal spray, and may run a set of experiments pinning then as a nasal spray to see if I see a difference. I will also pin them separately for now and may do Sem in the AM and Sel in the PM to test that as well.

 

[DustAndDignity]

Thank you very much for your input. I have read a bit about having RS use it as a nasal spray, and may run a set of experiments pinning then as a nasal spray to see if I see a difference. I will also pin them separately for now and may do Sem in the AM and Sel in the PM to test that as well.

If you need any resources on preparing them IN feel free to reach out. I’d be happy to share how I went about preparing it.

 

[CNCCurrency]

I am looking to start some research on Selank and Semax. I have searched on here and a few other places and see a lot of conflicting answers to my questions and was hoping someone with experience in the research may be able to answer a few questions.

RS plans to do a 300mcg dose of each peptide in a 5/2 on/off schedule. In my research it seems this is best done in the morning. For my questions:

Can these be combined in the same shot without issue?

If doing 5/2 schedule do you need to be on 4 weeks off 4 weeks? I saw post say 2 weeks some say 4 etc.

What was your RS experience in the 4 weeks off? Did symptoms return fully?

RS's symptoms seem to prone to irritability and short temper that they think could be linked to depression but never really had any issues with "sadness".

Thank you for you time.

I use them both in the same syringe

 

[CNCCurrency]

I am looking to start some research on Selank and Semax. I have searched on here and a few other places and see a lot of conflicting answers to my questions and was hoping someone with experience in the research may be able to answer a few questions.

RS plans to do a 300mcg dose of each peptide in a 5/2 on/off schedule. In my research it seems this is best done in the morning. For my questions:

Can these be combined in the same shot without issue?

If doing 5/2 schedule do you need to be on 4 weeks off 4 weeks? I saw post say 2 weeks some say 4 etc.

What was your RS experience in the 4 weeks off? Did symptoms return fully?

RS's symptoms seem to prone to irritability and short temper that they think could be linked to depression but never really had any issues with "sadness".

Thank you for you time.

Maybe add pe 22-28 also

 

[Smiter]

I just used Salbutamol in the inhaler and had a session in the gym. I submit that both Semax and Selank would be better off used as intranasals because it might be easier to cross the BBB that way.

 

[Jfrick11]

I have mixed them together and use IN at night bf bed.

 

[nnnnnaaaaa]

I've had issues with semax causing brain fog/aphasia, but love selank. morning IN with high doses

 

[tendency]

I just used Salbutamol in the inhaler and had a session in the gym. I submit that both Semax and Selank would be better off used as intranasals because it might be easier to cross the BBB that way.

IN is the only way these two work for me as well.

 

[walkingdreadd]

Did 300mcg of Semax this morning and felt nothing. A few hours later did 300mcg of Selank and that stuff messed up my RS. Heart rate elevated, light headedness, and jittery. RS decided to not go further with research into the two products.

EDIT: But after the anxiety attack RS feels more calm and focused. Also happy to still be alive, so maybe it worked in a different way.

 

[LabRatBarbie]

If you need any resources on preparing them IN feel free to reach out. I’d be happy to share how I went about preparing it.

I got got my sem today. I’m interested in how it’s made for in. Can you use

7% Saline Solution with 7% Sodium Chloride Saline?​[archived internal link]

 

[DustAndDignity]

I got got my sem today. I’m interested in how it’s made for in. Can you use

7% Saline Solution with 7% Sodium Chloride Saline?​

Hey, glad you got your Semax in.

First, here’s what I use to calculate my doses. It’s the IN calculator. https://intranasal.peprecon.com/

Here’s the saline that used.

PURAX Saline Solution 0.9%,Nasal... https://www.amazon.com/dp/B0FDPRPNTD?ref=ppx_pop_mob_ap_share

Or.

Shusher Care Saline Ampoules -... https://www.amazon.com/dp/B0D1HCHRS7?ref=ppx_pop_mob_ap_share

I used these spray bottles.

ZHWKMYP 10 Pcs Nasal Spray... https://www.amazon.com/dp/B0DXZWDM9Y?ref=ppx_pop_mob_ap_share

I typically used 5mL of Saline for 10mg of Semax or Selank. This roughly gives you a dose of 250mcg per spray.

Here’s how I went about reconing:

1. Draw 1-2mL into a syringe

2. Recon the vial with the saline in the syringe.

3. Place the remaining saline in the spray bottle.

4. Filter Semax once reconned into the spray bottle with the saline inside.

5. Gently mix the two.

Here’s an example of the label I print to place in the bottle.

Hope this helps.

Reach out with any questions.

 

[Chili777]

Hey, glad you got your Semax in.

First, here’s what I use to calculate my doses. It’s the IN calculator. https://intranasal.peprecon.com/

Here’s the saline that used.

PURAX Saline Solution 0.9%,Nasal... https://www.amazon.com/dp/B0FDPRPNTD?ref=ppx_pop_mob_ap_share

Or.

Shusher Care Saline Ampoules -... https://www.amazon.com/dp/B0D1HCHRS7?ref=ppx_pop_mob_ap_share

I used these spray bottles.

ZHWKMYP 10 Pcs Nasal Spray... https://www.amazon.com/dp/B0DXZWDM9Y?ref=ppx_pop_mob_ap_share

I typically used 5mL of Saline for 10mg of Semax or Selank. This roughly gives you a dose of 250mcg per spray.

Here’s how I went about reconing:

1. Draw 1-2mL into a syringe

2. Recon the vial with the saline in the syringe.

3. Place the remaining saline in the spray bottle.

4. Filter Semax once reconned into the spray bottle with the saline inside.

5. Gently mix the two.

Here’s an example of the label I print to place in the bottle.

Hope this helps.

Reach out with any questions.

I don't see a dosage for the spray volume. Maybe i missed that. Without knowing that, your calculation is a guesstimate. Also, 250 mcg per spray, assuming it does give 0.1 ml, with 10 mg of pep would be 4 ml of saline total for a 500 mcg dosage?

 

[DustAndDignity]

I don't see a dosage for the spray volume. Maybe i missed that. Without knowing that, your calculation is a guesstimate. Also, 250 mcg per spray, assuming it does give 0.1 ml, with 10 mg of pep would be 4 ml of saline total for a 500 mcg dosage?

My spray bottles are usually .12 to .13. You could always add more saline and just increase the number of sprays. It turns into a personal preference at some point in time with how you recon it.

 

[Chili777]

My spray bottles are usually .12 to .13. You could always add more saline and just increase the number of sprays. It turns into a personal preference at some point in time with how you recon it.

Right. If you know the spray volume you can adjust to your preference. I like 1 mg total because my brain needs as much help as it can get.

 

[fatjacked]

Hey, glad you got your Semax in.

First, here’s what I use to calculate my doses. It’s the IN calculator. https://intranasal.peprecon.com/

Here’s the saline that used.

PURAX Saline Solution 0.9%,Nasal... https://www.amazon.com/dp/B0FDPRPNTD?ref=ppx_pop_mob_ap_share

Or.

Shusher Care Saline Ampoules -... https://www.amazon.com/dp/B0D1HCHRS7?ref=ppx_pop_mob_ap_share

I used these spray bottles.

ZHWKMYP 10 Pcs Nasal Spray... https://www.amazon.com/dp/B0DXZWDM9Y?ref=ppx_pop_mob_ap_share

I typically used 5mL of Saline for 10mg of Semax or Selank. This roughly gives you a dose of 250mcg per spray.

Here’s how I went about reconing:

1. Draw 1-2mL into a syringe

2. Recon the vial with the saline in the syringe.

3. Place the remaining saline in the spray bottle.

4. Filter Semax once reconned into the spray bottle with the saline inside.

5. Gently mix the two.

Here’s an example of the label I print to place in the bottle.

Hope this helps.

Reach out with any questions.

Super helpful. I am going to be using this exact protocol and will report back.

 

[lakelife13]

I’ve completed 2 weeks of SUBQ semax 500mcg a day and felt nothing. Bumped it up to 750mcg a day a few days ago and still no change. I may try IN in the future but not anytime soon.

 

[nitetrak]

I just want to say don't ever buy the cheap nasal sprayers on Amazon.

I tested with tap water and the amount of sprays per 10ml was random.

The worst is eventually they broke, all six, the nozzle in the tip broke off and hit the ceiling really hard. That would be bad if I were actually using it.

Got a refund on that and bought Snoot. Snoot is very consistant, occasional misfires but better than others.

I have been told that Semax MIGHT not reconstitute well if BAC water is not used.

Here is what I do...

10mg Semax 2ml Hospira, when clear (20 mins) transfer to spray bottle, add 5ml ampule of sterile saline.

This makes 7 spays=1mg so when on full dose, 4 sprays first thing in the morning then 3 more sprays at 3pm. 20 days on then a week or two off before starting again. I'm thinking of just going the 1st-20th of each month.

I'm waiting for my first delivery of selank right now, so that is next on my list.