Reta + CJC/IPA counter-synergistic?

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xXteethmaster69Xx

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So retratrutide works through multiple pathways, as we all know, one of which being appetite suppression & delayed gastric emptying. Ipamorelin, being a ghrelin mimetic, has been shown to raise hunger levels and accelerate gastric emptying significantly.

My question is: To those who have run both at the same time, did you still notice the appetite suppressive effects of the retatrutide, or were they counteracted by the hunger-inducing Ipamorelin?

Bonus question to those who've run this stack: Did you retain more lean mass on your cut vs running reta alone??
 
Yes, Ipamorelin increased my appetite to such an extent that I thought Retatrutud had stopped working.

Since I started using Retatrutud, I’ve been doing strength training and have seen a noticeable increase in muscle mass. I can’t say for sure whether Ipamorelin and CJC have boosted it even further.
 
I have been running CJC/Ipa with Reta for about 4 weeks now. Just Reta for about 6 weeks before that. I have found I am retaining more lean mass. Weight loss has been minimal since switching, but can clearly see recomp happening, so not too worried about weight loss right now. Actually gained 3 lbs of muscle since starting this stack. I still feel the hunger suppression from Reta, and get full fairly quickly. Does make it a bit harder to hit my protein target, but do force myself to get the protein down, especially focusing on protein heavy snacks and protein drinks.
 
4 weeks into CJC/IPA 150mcg 2/day fasted, haven't actually noticed any effect, nothing negative nothing positive. Actually I guess I should count a quarter sized itchy spot for 30min after every injection. We will see if my labwork shows any increase.

This is after months of Reta, still on a 2mg/wk maintenance dose.
 
I tried Tesa/ipa twice for only five days or so each. First at 2mg Reta per week and 1/.250 tesa/ipa morning and night. Could feel a manageable increase in hunger.

Tried later at ~4mg Reta and 1.5/.350 t/I in the evenings. No bump in appetite that time.

When I get closer to my target weight, I’ll start again, but I put on water with it and that was discouraging.
 
xXteethmaster69Xx said:
So retratrutide works through multiple pathways, as we all know, one of which being appetite suppression & delayed gastric emptying. Ipamorelin, being a ghrelin mimetic, has been shown to raise hunger levels and accelerate gastric emptying significantly.

My question is: To those who have run both at the same time, did you still notice the appetite suppressive effects of the retatrutide, or were they counteracted by the hunger-inducing Ipamorelin?

Bonus question to those who've run this stack: Did you retain more lean mass on your cut vs running reta alone??
Probably same effect as Reta and HGH. When I started HGH, my appetite went through the roof the first few weeks and me and my friends were joking that I should have increased the Reta dose to counteract it. But after a few weeks, my body adjusted to it and it balanced out. So I take the same micro dose of Reta now and it seems to have same effect as before. But not sure if HGH will be the same.
 
CJC IPA should help you maintain muscle mass while on a deficit with Reta

I personally run both, but the effects of the cjc ipa allowed me to eat decently again
 
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